1,721,020 research outputs found
1 - year follow-up after intravitreal bevacizumab alone and in combination with photodynamic therapy for AMD and PCV.
No full text
The ReZoom multifocal intraocular lens: 2-year follow-up.
No full textAbstract
PURPOSE:
To evaluate distance, intermediate, and near visual acuity and patient satisfaction over a period of 2 years after implantation of the ReZoom multifocal intraocular lens.
METHODS:
Fifty-five eyes of 35 cataract patients were included in this retrospective study. Only patients with a preoperative photopic pupillary diameter superior to 3 mm were included. Monocular visual acuities and visual symptoms were compared at different time points.
RESULTS:
Preoperative mean distance uncorrected visual acuity (UCVA) was 0.5+/-0.3 LogMAR, uncorrected intermediate visual acuity (UCiVA) at 50 cm was 0.6+/-0.3 LogMAR, and near uncorrected visual acuity (UNVA) was J7.8+/-0.6. Mean follow-up was 28.1+/-7.2 months. At 6 months, UCVA improved to 0.05+/-0.09 logMAR (p<0.001), UCiVA to 0.08+/-0.1 LogMAR (p<0.001), and UNVA to J2.4+/-0.4 (p<0.001). At 24 months, UCVA was 0.04+/-0.08 LogMAR, UCiVA was 0.07+/-0.1 LogMAR, and UNVA was J2.3+/-0.7. No significant differences were observed between the values at 6 months versus 24 months. At the 3-month visit, moderate glare and halo were reported by 10% and 13% of patients, respectively. The occurrence of visual symptoms decreased with time, with only 7% and 5% of patients reporting moderate glare and halo at the last visit, respectively.
CONCLUSIONS:
The ReZoom lens provides quality vision at all distances. Between 6 and 24 months of follow-up, a further improvement of optical disturbances rather than uncorrected visual acuity may be expected
Long-term outcome of primary versus secondary intraocular lens implantation after simultaneous removal of bilateral congenital cataract.
No full textBACKGROUND:
Long-term outcomes of intraocular lens (IOL) implantation for congenital cataract in children under 2 years old are still undetermined.
METHODS:
We retrospectively reviewed all cases of bilateral congenital cataract who had undergone simultaneous bilateral cataract removal with posterior capsulotomy and central anterior vitrectomy between 1990 and 2010. Patients randomly underwent primary IOL implantation or secondary IOL implantation after a period of contact lens wear. The two groups were compared for visual outcome and complications during follow-up.
RESULTS:
Cataract removal and primary IOL implantation was performed in 30 eyes (15 patients; nine males, six females) at a mean age of 6.8 ± 4.2 months. After 79.31 ± 63.4 months, best-corrected visual acuity (BCVA) was 0.53 ± 0.36 EDTRS LogMAR. In 36 eyes (18 patients, 11 males, seven females) the lens was removed at a mean age of 5.42 ± 2.80 months, and after 32.0 ± 6.1 months of contact lens utilization, secondary IOL implantation was performed. After 109.0 ± 33.8 months, BCVA was 0.54 ± 0.4 ETDRS LogMAR. The association between age at surgery and final visual acuity and the difference between the two groups concerning type of cataract at baseline, BCVA and refractive error at last visit, incidence of posterior capsular opacification, glaucoma, strabismus, and nystagmus during follow-up were not significant (p > 0.05). Myopic shift was more frequent in eyes undergone primary IOL implantation (p < 0.001).
CONCLUSIONS:
Similar visual outcome and complications were observed during long-term follow-up after both primary and secondary IOL implantation following simultaneous bilateral congenital cataract removal with posterior capsulotomy and central anterior vitrectomy
Evaluation of posterior pole with echography and optical coherence tomography in patients with Behçet's disease.
No full textChoroidal neovascularisation complicating geographic atrophy in age-related macular degeneration.
No full textAbstract
OBJECTIVE:
To investigate the morphological and functional outcomes after intravitreal ranibizumab injections for choroidal neovascularisation (CNV) complicating geographic atrophy (GA).
DESIGN:
Retrospective, interventional, consecutive case series.
METHODS:
We reviewed the charts of all consecutive patients with GA due to age-related macular degeneration (AMD), who received intravitreal ranibizumab injections for the development of CNV at least 24 months earlier.
RESULTS:
21 treatment-naive eyes of 21 consecutive patients (4 men, 17 women, mean age 86.9±1.6 years) were included. In 95.2% of eyes a type 2 CNV was present, extrafoveal in 42.8% of cases. After a mean of 5.0±0.87 (range 1-20) intravitreal ranibizumab injections, best-corrected visual acuity (BCVA) significantly worsened at the 24-month follow-up visit (0.73±0.05 vs 0.88±0.08 logMAR, respectively; p=0.01). A significant reduction of intraretinal cystic lesions, subretinal fluid and pigment epithelium detachment (p<0.001) and a significant increase of GA area (p=0.003) were present at last visit.
CONCLUSIONS:
Ranibizumab treatment of GA-associated CNVs provides no BCVA improvement at 24 months follow-up despite an anatomic response of CNV. Low effectiveness of ranibizumab in these cases is likely due to GA progression
Long-Term Outcomes of Primary Intraocular Lens Implantation for Unilateral Congenital Cataract.
No full textPurpose: In congenital cataracts, the need for early intervention is well established to prevent visual deprivation and amblyopia. We evaluated patients with unilateral amblyogenic congenital who had undergone simultaneous cataract removal and intraocular lens implantation. Methods: We retrospectively reviewed all patients operated on between 1990 and 2010 at the Pediatric Eye Department of the University Federico II of Naples (Italy). Minimum follow-up for inclusion was 48 months. Results: 52 patients (28 females, 24 males, mean age at surgery 9.0 ± 4.5 months, range 2–21 months) were included in this retrospective review. Mean follow-up was 100.7 ± 57.0 months (range, 48–270 months). At last visit, mean BCVA in the operated eyes was 0.65 ± 0.4 (range, 0.04–1.3) LogMAR and 40 patients (76.9%) had strabismus. In patients undergoing surgery at an age >12 months, BCVA was significantly lower (0.92 ± 0.4 LogMAR versus 0.60 ± 0.4 LogMAR, p = 0.01), although development of myopic shift was less frequent (61.5% versus 43.5%, p = 0.03). BCVA at last visit was higher in patients with a first stable pseudophakic SE between +1D and +3D (p = 0.02). Conclusions: Worse final BCVA, despite less frequent development of myopic shift, was observed when surgery was performed after 12 months of age. A hyperopic correction in first stable pseudophakic SE seems advisable
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