1,720,956 research outputs found
Progetto finalizzato alla valutazione dei pazienti sottoposti a trattamento chirurgico dopo terapia neoadiuvante per neoplasia polmonare NSCLC in fase localmente avanzata N2 (stadio IIIA sec. VII classificazione OMS): analisi di protocolli e studi internazionali; realizzazione di un database; elaborazione di protocollo terapeutico multidisciplinare (chemioterapia + chirurgia - chemioradioterapia concomitante + chirurgia) integrato.
Clinical significance of circulating tumor cells in colon and breast solid neoplasms
Background: Tumor cells that are identified in transit within the blood stream are referred to as circulating tumor cells (CTCs); a fraction of these are thought to be viable metastatic precursors capable of initiating a clonal metastatic lesion. CTC could be used as non-invasive marker for monitoring drug sensitivity or resistance and select cancer patients who are candidates for early systemic antimetastatic therapy. Identifying CTCs in neoplastic patients could be also an independent prognostic factor for patients at risk for recurrence or metastasis
Analysis of variables predictive of severity in biliary peritonitis
OBJECTIVE: To analyze clinical and laboratory findings in order to find variables predictive of severity of Biliary Peritonitis (BP). METHODS: Physical findings, course of illness, imaging and laboratory data were evaluated in 22 patients with BP? and statistically analysed to assess their prognostic significance. RESULTS: Serious illness and worse outcome were associated with: age > 60 years (P= 0.034), long time between onset of symptoms and treatment (P= 0.025), fever > 38 degrees C (P= 0.009), WBC count > 17.000 cell/mm(3) (P=0.043), diffuse abdominal pain (P= 0.034), and infected bile (P= 0.048). CONCLUSIONS: Most patients become severely ill due to supervening infection, while early bile drainage avoids serious complications. In addition, abdominal pain, fever and WBC count are also predictive of severity of BP
Limb-salvage surgery in trauma leg injuries. Does it offer patients better quality of life and functional capacity than amputation?
Background: The decision to salvage or amputate the injured limb has generated much controversy in the Literature,
with studies to support advantages of each approach. All scoring systems have proved unreliable in predicting the
need for amputation or salvage. ‘Making decision' and 'timing' can be difficult even for experts.
Limb-salvage surgery in trauma leg injuries. Does it offer patients
better quality of life and functional capacity than amputation?
www.preventionandresearch.com 8 Jan-Mar 2013|P&R Scientific|Volume 3|N°1
Objectives: Obviously, it is to avoid amputation of a limb which could be saved, as well as not always trying the
revascularization. This is the challenging problem. In our opinion, the issue is not to perform revascularization just
because it is technically feasible, but when it should be performed.
The purpose of this study is clarify some decisions about management of severely injured legs
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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