1,721,913 research outputs found
Síntesis de nuevos derivados espirostánicos a partir de diosgenina y evaluación de su actividad anabólica in silico
No full text"El presente trabajo aborda la síntesis y evaluación de novedosos compuestos esteroidales con la funcionalidad hidrazona en un exitoso proceso de 3 etapas con buenos rendimientos químicos partiendo del compuesto natural diosgenina. A través de un análisis quimioinformatico utilizando la herramienta PASS ONLINE® así como el análisis In Silico mediante docking molecular, se decidió orientar la función hidrazona hacia la posición C-7 de la estructura esteroidal mejorando las probabilidades de éxito, además, el análisis In silico permitió identificar proteínas asociadas con el crecimiento muscular para dilucidar los mecanismos plausibles y las interacciones entre estos compuestos y los aminoácidos del sitio activo. Los resultados obtenidos respaldan una prometedora opción para nuevos agentes anabólicos que podrían ser aplicados en el tratamiento de trastornos musculares como las miopatías"
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Missing data in the structural gravity: estimation bias due to the omission of internal trade
Get PDFFil: Moncarz, Pedro Esteban. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Moncarz, Pedro Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Vaillant, Marcel. Universidad de la República. Facultad de Ciencias Sociales. Departamento de Economía; Uruguay.Fil: Flores, Manuel. Universidad de la República. Facultad de Ciencias Sociales. Departamento de Economía; Uruguay.In the last decade there has been an intense development in trade
models aiming to explain the determinants of bilateral trade. A seminal
theoretical and methodological contribution is Anderson and van Wincoop
(2003), who introduced the concept of multilateral resistance and structural
gravity. However, there is still an important gap between the theoretical
developments of the structural gravity model and its empirical applications.
The main two issues are: the presence of zeros in bilateral trade and the
missing data problem of own production oriented to the own market. The
presence of zero trade has been considered in Santos Silva and Tenreyro
(2006) and Helpman, Melitz and Rubinstein (2008), but the effects of the
lack of internal transactions in the estimation of the gravity model has not
been much studied, even when its relevance can be thought to be of greater
importance, because the great heterogeneity across countries in terms of their
degrees of openness. The objective of the paper is, through the use of state of
the art tools, analyze and characterize the consequence of the omission of
internal transactions in the estimation of trade proximities (trade costs) and
on the values of multilateral resistances, which in turn will affect the
comparative static effects derived from different trade policy measures.Fil: Moncarz, Pedro Esteban. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Moncarz, Pedro Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Vaillant, Marcel. Universidad de la República. Facultad de Ciencias Sociales. Departamento de Economía; Uruguay.Fil: Flores, Manuel. Universidad de la República. Facultad de Ciencias Sociales. Departamento de Economía; Uruguay.Economía, Econometrí
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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