1,721,432 research outputs found
Atypical patterns of response and progression in the era of immunotherapy combinations
No full textIn the immunoncology era, an acceleration of tumor growth upon immune checkpoint inhibitors (ICI), defined as hyperprogressive disease (HPD) has been observed across different cancers. Although in non-small-cell lung cancer, most of the available evidence regarding HPD has been reported for patients treated with single agent PD-1 and PD-L1 inhibitors, in retrospective series a variable proportion of patients receiving ICI combinations also experienced HPD. Similarly, the shape of survival curves and the progression rates in clinical trials testing combinations of PD-1/PD-L1 inhibitors and anti-CTLA-4 agents suggest the occurrence of HPD. Few data are available regarding pseudoprogression upon ICI combinations. However, considering that pseudoprogression has been reported for anti-PD-1/PD-L1 agents and for CTLA-4 inhibitors separately, it is likely that it may occur also upon combinations of these two classes of drugs
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Vecchi e nuovi volti dell’immigrazione: ‘ritratti’ per aree di origine e di insediamento
No full textObiettivo di questo capitolo è far emergere le principali caratteristiche del dell'immigrazione in Campania, desumibili dalle rilevazioni ufficiali disponibili. L’analisi viene condotta prima a livello regionale, quindi mettendo in luce le differenze tra le province, per scendere infine ad un dettaglio subprovinciale. In parte differenti sono le componenti della presenza straniera analizzate ai diversi livelli di disaggregazione territoriale: mentre su scala regionale risulta possibile far riferimento alla componente legale-stabile, a quella legale in complesso (stabile e semi-stabile) e a quella irregolare (assimilata alle domande di regolarizzazione), a livello sub-provinciale è possibile esaminare solo la componente legale-stabile
Il Questionario SVS Bambino
No full textChildren with visuospatial impairments often showed academic difficulties in arithmetic, geometry, geography, drawing and social interactions. The child version of the SVS questionnaire - based on the SVS for teachers (Molin and Cornoldi, 2003) - has been devised in order to allow an early identification of children with visuospatial difficulties. It examines academic and visuospatial difficulties typically associated with a profile of nonverbal learning disabilities. The results revealed that the SVS questionnaire for children is an useful tool both for scholastic and clinical settings
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Commentario al testo unico dell'edilizia
No full textCommento puntuale dei singoli articoli del Testo unico dell'edilizi
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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