912 research outputs found
The influence of an experimentally-induced malocclusion on vertebral alignment in rats: a controlled pilot study
There is a growing interest in the relationship between occlusion and posture because of
a greater incidence of neck and trunk pain in patients with occlusal dysfunction. The study was designed
to verify whether an alteration of the spinal column alignment may be experimentally induced in rats as
a consequence of altering dental occlusion and also to investigate whether the spinal column underwent
any further changes when normal occlusion was then restored. Thirty rats were divided into two groups.
Fifteen (15) rats (test group) wore an occlusal bite pad made of composite resin on the maxillary right
first molar for a week (T1). The same rats wore a second composite bite pad for another week on the left
first molar in order to rebalance dental occlusion (T2). Fifteen rats were included in an untreated control
group. All the rats underwent total body radiographs at T0 (before the occlusal pad was placed), at T1
(one week after application of a resin occlusal bite pad on the maxillary left first molar) and at T2 (one
week after application of a second resin occlusal bite pad on the maxillary right first molar). A scoliotic
curve developed in all the test rats at T1. There were no alterations of spinal position observed in any of
the control rats. Additionally, the spinal column returned to normal condition in 83% of the test rats when
the balance in occlusal function was restored. The alignment of the spinal column seemed to be influenced
by the dental occlusion
Gingival crevicular fluid alkaline phosphatase activity reflects periodontal healing/recurrent inflammation phases in chronic periodontitis patients.
BACKGROUND:
Roles for host enzymes as diagnostic indicators of periodontal status in gingival crevicular fluid (GCF) have been proposed. One of these host enzymes is alkaline phosphatase (ALP), the GCF activity of which has been associated with periodontal inflammation. Thus, the present study aimed to improve our understanding of how the healing of chronic periodontitis following scaling and root planing (SRP) affects GCF ALP activity after 15 and 60 days.
METHODS:
Sixteen systemically healthy subjects (aged 35 to 61 years) with moderate to advanced generalized chronic periodontitis were recruited. In each subject, paired pockets with probing depths (PDs) > or =4 mm that were located in two symmetric quadrants were chosen. These sites were randomized at the split-mouth level, with half receiving SRP treatment and the other half left untreated. Ninety-two pockets were included in the study. Clinical examinations were performed at baseline (prior to SRP) and after 15 and 60 days; information recorded included the presence of plaque, PD, clinical attachment level (CAL), and bleeding on probing. GCF was collected from each pocket included in the study at the three time points.
RESULTS:
A large and significant decrease in GCF ALP activity was seen 15 days after SRP, concomitant with an improvement in clinical parameters. After 60 days, an increase in GCF ALP activity back to baseline levels was recorded along with further improvements in clinical parameters. Moreover, in the SRP pockets with initial PDs >6 mm, the CAL gains between days 15 and 60 were significantly associated with changes in GCF ALP activity over the same time interval.
CONCLUSIONS:
The decrease in GCF ALP activity at 15 days corresponded to a decrease in clinical signs of inflammation; in contrast, the increase in GCF ALP activity at 60 days seemed to be related to subclinical recurrent inflammation or further healing/remodeling of the periodontal tissue. Therefore, GCF ALP reflects the short-term periodontal healing/recurrent inflammation phases in chronic periodontitis patients
The influence of an experimentally-induced malocclusion on vertebral alignment in rats: a controlled pilot study
There is a growing interest in the relationship between occlusion and posture because of
a greater incidence of neck and trunk pain in patients with occlusal dysfunction. The study was designed
to verify whether an alteration of the spinal column alignment may be experimentally induced in rats as
a consequence of altering dental occlusion and also to investigate whether the spinal column underwent
any further changes when normal occlusion was then restored. Thirty rats were divided into two groups.
Fifteen (15) rats (test group) wore an occlusal bite pad made of composite resin on the maxillary right
first molar for a week (T1). The same rats wore a second composite bite pad for another week on the left
first molar in order to rebalance dental occlusion (T2). Fifteen rats were included in an untreated control
group. All the rats underwent total body radiographs at T0 (before the occlusal pad was placed), at T1
(one week after application of a resin occlusal bite pad on the maxillary left first molar) and at T2 (one
week after application of a second resin occlusal bite pad on the maxillary right first molar). A scoliotic
curve developed in all the test rats at T1. There were no alterations of spinal position observed in any of
the control rats. Additionally, the spinal column returned to normal condition in 83% of the test rats when
the balance in occlusal function was restored. The alignment of the spinal column seemed to be influenced
by the dental occlusion
Clinton F and Beatrice Ward
Clinton F. and Beatrice Ward Parvin of Old Manatee (East Bradenton). She is the author of "I Remember, a family memoir." Copy on file at the Manatee County Central Library
Periodontal Healing of a Human Intrabony Defect Treated by Autogenous Periosteal Barrier Membrane and Bone Graft: A Clinical and Histologic Case Report
Introduction: The aim of this case report is to clinically and histologically evaluate the healing of a deep intrabony
defect treated with a combination therapy using autogenous periosteal membrane and autogenous bone graft.
Case Presentation: A 45-year-old female was scheduled for hemisection of tooth #30, affected by a degree III furcation
involvement, with the extraction of the mesial root. The root was associated with a 6-mm intrabony defect. The patient
volunteered to have the defect treated by a regenerative technique before the extraction. A notch was placed at the level of
the crestal bone on the root surface to serve as reference for histologic evaluation. The intrabony defect was filled by autogenous
bone chips and covered by an autogenous periosteal barrier membrane obtained from the palate. One year after
regenerative treatment, a block biopsy containing the root with some of the surrounding soft and hard tissues was sampled
during the tooth hemisection procedure and processed for histologic evaluation. At the 12-month examination, a 7-mm
probing depth decrease and a 4-mm clinical attachment gain were observed. The radiographic examination showed the
complete filling of the defect. Histologic evaluation showed the formation of new cellular cementum with inserting collagen
fibers from the base of the defect to the notch level. Newly formed bone was also observed.
Conclusion: Our results suggest that the adjunctive use of autogenous bone graft and periosteal barriermembrane may
represent a promising surgical technique for periodontal regeneration in clinical practice
La Croix et les idoles d'après l'apologie d'Athanase 'Contre les paiens'
Through the analysis of some significant passages of Athanasius' apology «Against the Pagans on the Incarnation of the Word», and also thanks to their comparison with other selected texts by the same author, P. F. Beatrice tries to date this still problematic work to around the middle of the fourth century. In particular, he intends to show that Athanasius did know the Neoplatonic philosophy of his time sufficiently well and that the target of his polemic was especially Porphyry. But anti-pagan criticism also supplies Athanasius with a substantial support in his struggle with the Arian heresy which had been shared by his great precursor and adversary Eusebius of Caesarea
Alginate Impressions vs IOS Optical Scanners Using Reverse Engineering Technology: A Comparative Study
Surgical treatment of periodontal intrabony defects with calcium sulfate implant and barrier versus collagen barrier or open flapdebridement alone: a 12-month randomized controlled clinical trial.
Abstract
BACKGROUND:
This randomized controlled clinical trial was designed to compare the clinical outcomes of guided tissue regeneration with calcium sulfate graft and membrane (CS) versus guided tissue regeneration with collagen membrane (CM) or open flap debridement (OFD) only in terms of clinical attachment gain in periodontal intrabony defects.
METHODS:
Fifty-one systemically healthy, non-smoking subjects affected by moderate to severe chronic periodontitis were recruited. The subjects had one deep intrabony defect with a probing depth (PD) > or =6 mm and were randomly divided into three equal groups (17 subjects per group). Subjects were surgically treated with OFD (OFD group), OFD with CS (CS group), or OFD and CM (CM group). One year after surgical treatment, a complete clinical examination and a surgical reentry were performed. The pre- and post-therapy clinical parameters, including PD, clinical attachment level (CAL), gingival recession (GR), and intrasurgical parameters (defect bone level [DBL]), were compared.
RESULTS:
After 1 year, the clinical and intrasurgical parameters showed statistically significant changes from baseline within each group for all of the evaluated parameters (PD and CAL, P <0.001; GR and DBL, P <0.05). Differences (PD, CAL, and DBL, P <0.001; GR, P <0.05) were also seen across the three groups. The CM and CS groups had significantly smaller PD, CAL, and DBL values than subjects treated with only OFD. Groups treated with regenerative techniques had a significantly greater PD reduction and CAL and DBL gain compared to the OFD group. No significant differences were seen between CM and CS. Conversely, the CM group showed a significantly greater GR increase compared to OFD and CS.
CONCLUSIONS:
Both regenerative treatments produced additional clinical benefits over OFD alone. Moreover, the use of CS may minimize post-surgical recession
Treatment of supra-alveolar-type defects by a simplified papilla preservation technique for access flap surgery with or without enamel matrix proteins
Background: In this study, we compare the effectiveness of enamel matrix derivative (EMD) associated with a simplified papilla preservation flap (SPPF) technique to SPPF alone when surgically treating supra-alveolar-type defects. Methods: Fifty patients, from 54 initially selected, presenting horizontal bone loss around ≥4 adjacent teeth, were treated by an SPPF technique; 25 participants also received EMD (test group) and 25 patients underwent flap surgery alone (control group). A complete clinical and radiographic examination was performed at baseline and 12 months after treatment. Pre- and post-therapy probing depth (PD), clinical attachment level (CAL), gingival recession (GR), and radiographic bone level (BL) were compared between treatments. Results: After 12 months, PD, CAL, and GR in both groups showed significant differences from baseline (P <0.001). No differences in BL scores were observed within the groups at the 12-month examination. After 1 year, the test group showed significantly (P <0.001) greater PD reduction (3.4 ± 0.7 mm) and CAL gain (2.8 ± 0.8 mm) and a smaller GR increase (0.6 ± 0.4 mm) compared to the control group (PD, 2.2 ± 0.8 mm; CAL, 1.0 ± 0.6 mm; GR, 1.2 ± 0.7 mm.) BL changes did not significantly differ between the experimental groups. Conclusion: The results of this study suggest that combining EMD and SPPF in the treatment of suprabony defects may lead to a greater clinical improvement compared to SPPF alone
750 years on : Beatrice of Nazareth revisited
This introductory essay to the special issue Beatrice of Nazareth (1200-1268). Milieu – Mysticism – Influence first offers a brief presentation of the life and literary legacy of the famous Cistercian nun, mystic and author who takes centre stage in the present volume. It then elucidates the emergence and subsequent international popularity of Beatrice studies, and discusses the diverse approaches that can be discerned in the current multidisciplinary scholarship on Beatrice. Finally, it explains how the five essays which are collected in this volume open up new avenues for research into the thirteenth-century Cistercian world and for future Beatrice studies
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