1,721,365 research outputs found
Il governo dell’innovazione farmaceutica in Italia. Dallo stato dell’arte a un modello di gestione regionale equa e sostenibile dei farmaci innovativi e ad alto costo
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Impact of COVID-19 on Timing of Hip-Fracture Surgeries: An Interrupted Time-Series Analysis of the Pre/Post-Quarantine Period in Northern Italy
Full text linkTo assess whether the imposition of the coronavirus disease 2019 (COVID-19) national quarantine (March 10, 2020) resulted in a shift in the proportion of patients operated for hip fracture on the day of admission, the following day and two days after admission in the region of Piedmont, northern Italy
[Residency in hygiene and preventive medicine: present and future].
No full textINTRODUCTION: The changing needs and expectations of the population and the current financial distress lead the Italian health care system to face a profound challenge that requires also a new evaluation of professionals' training. Specialists in Hygiene and Preventive Medicine (HPM) are called for to develop new knowledge and skills in hygiene, public health, and management, as they fulfill leadership roles within the hospitals.
OBJECTIVE:
To investigate the current status of Hospital Health Management Boards (HHMB) and the specific know-how they require, in order to develop an adequate post-graduate residency training in HPM.
MATERIALS AND METHODS:
We conducted a literature review on the main and «gray literature» databases; then, we conducted three semi-structured interviews with the Chiefs of the HHMB operating in the major hospitals of Bologna (Northern Italy); lastly, we organised a workshop with residents in HPM and health workers of Emilia-Romagna hospitals.
RESULTS:
Interviews with Hospital Health Managers have highlighted the main issues faced by a modern HHMB. The main questions discussed were: the changing role of the hospital and its relationship with primary care; the increasing competition among professionals with different specialisations within the HHMB; the need to develop multi-professional teams; the necessity to enlarge HPM residency training programmes in order to meet the HHMB needs.
CONCLUSION:
The evolution of the HHMB reflects the evolution of the Italian health care system. HHMBs should better fit the organization to the context, and the post-graduate schools in HPM should follow this process. In the framework of the current rules and laws it is possible to focus for implementing training programmes that include management, coordination and negotiation skills, and help build an adequate leadership profile
Frauds in scientific research and how to possibly overcome them
Full text linkFrauds and misconduct have been common in the history of science. Recent events connected to the COVID-19 pandemic have highlighted how the risks and consequences of this are no longer acceptable. Two papers, addressing the treatment of COVID-19, have been published in two of the most prestigious medical journals; the authors declared to have analysed electronic health records from a private corporation, which apparently collected data of tens of thousands of patients, coming from hundreds of hospitals. Both papers have been retracted a few weeks later. When such events happen, the confidence of the population in scientific research is likely to be weakened. This paper highlights how the current system endangers the reliability of scientific research, and the very foundations of the trust system on which modern healthcare is based. Having shed light on the dangers of a system without appropriate monitoring, the proposed analysis suggests to strengthen the existing journal policies and improve the research process using new technologies supporting control activities by public authorities. Among these solutions, we mention the promising aspects of the blockchain technology which seems a promising solution to avoid the repetition of the mistakes linked to the recent and past history of research
[Residency in hygiene and preventive medicine: present and future]
No full textINTRODUCTION: The changing needs and expectations of the population and the current financial distress lead the Italian health care system to face a profound challenge that requires also a new evaluation of professionals' training. Specialists in Hygiene and Preventive Medicine (HPM) are called for to develop new knowledge and skills in hygiene, public health, and management, as they fulfill leadership roles within the hospitals.
OBJECTIVE:
To investigate the current status of Hospital Health Management Boards (HHMB) and the specific know-how they require, in order to develop an adequate post-graduate residency training in HPM.
MATERIALS AND METHODS:
We conducted a literature review on the main and «gray literature» databases; then, we conducted three semi-structured interviews with the Chiefs of the HHMB operating in the major hospitals of Bologna (Northern Italy); lastly, we organised a workshop with residents in HPM and health workers of Emilia-Romagna hospitals.
RESULTS:
Interviews with Hospital Health Managers have highlighted the main issues faced by a modern HHMB. The main questions discussed were: the changing role of the hospital and its relationship with primary care; the increasing competition among professionals with different specialisations within the HHMB; the need to develop multi-professional teams; the necessity to enlarge HPM residency training programmes in order to meet the HHMB needs.
CONCLUSION:
The evolution of the HHMB reflects the evolution of the Italian health care system. HHMBs should better fit the organization to the context, and the post-graduate schools in HPM should follow this process. In the framework of the current rules and laws it is possible to focus for implementing training programmes that include management, coordination and negotiation skills, and help build an adequate leadership profile
The association between ABO blood group and SARS-CoV-2 infection: A meta-analysis
Full text linkAt present, existing evidence about the association between SARS-CoV-2 infection and ABO blood group polymorphism is preliminary and controversial. In this meta-analysis we investigate this association and determine SARS-CoV-2 positive individuals’ odds of having a specific blood group compared to controls. We performed a systematic search on MEDLINE and LitCovid databases for studies published through July 15, 2020. Seven studies met inclusion criteria for meta-analysis, including a total of 13 subgroups of populations (7503 SARS-CoV-2 positive cases and 2962160 controls). We analysed the odds of having each blood group among SARS-CoV-2 positive patients compared with controls. Random-effects models were used to obtain the overall pooled odds ratio (OR). Subgroup and sensitivity analyses were performed in order to explore the source of heterogeneity and results consistency. The results of our meta-analysis indicate that SARS-CoV-2 positive individuals are more likely to have blood group A (pooled OR 1.23, 95%CI: 1.09–1.40) and less likely to have blood group O (pooled OR = 0.77, 95%CI: 0.67–0.88). Further studies are needed to investigate the mechanisms at the basis of this association, which may affect the kinetics of the pandemic according to the blood group distribution within the population
SARS-CoV-2/COVID-19 Vaccines: The Promises and the Challenges Ahead
No full textThe development of a new vaccine usually consists of a linear sequence of several steps and lasts many years [...
Mis-tweeting communication: a Vaccine Hesitancy analysis among twitter users in Italy
No full textBackground and aim: A previously unseen body of scientific knowledge of varying quality has been produced during the ongoing COVID-19 pandemic. It has proven extremely difficult to navigate for experts and laymen alike, originating a phenomenon described as "Infodemic", a breeding ground for misinformation. This has a potential impact on vaccine hesitancy that must be considered in a situation where efficient vaccination campaigns are of the greatest importance. We aimed at describing the polarization and volumes of Italian language tweets in the months before and after the start of the vaccination campaign in Italy. Methods: Tweets were sampled in the October 2020-January 2021 period. The characteristics of the dataset were analyzed after manual annotation as Anti-Vax, Pro-Vax and Neutral, which allowed for the definition of a polarity score for each tweet. Results: Based on the annotated tweets, we could identify 29.6% of the 2,538 unique users as anti-Vax and 12.1% as pro-Vax, with a strong disagreement in annotation in 7.1% of the tweets. We observed a change in the proportion of retweets to anti-Vax and pro-Vax messages after the start of the vaccination campaign in Italy. Although the most shared tweets are those of opposite orientation, the most retweeted users are moderately polarized. Conclusions: The disagreement on the manual classification of tweets highlights a potential risk for misinterpretation of tweets among the general population. Our study reinforces the need to focus Public Health's attention on the new social media with the aim of increasing vaccine confidence, especially in the context of the current pandemic
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