117,610 research outputs found
Documenti urbinati sulla famiglia Santi
No full textIl contributo si propone, alla luce di nuove ricerche archivistiche, di chiarire la “vexata quaestio” relativa ai rapporti che la famiglia Santi, in generale, e il celebre pittore Raffaello, in particolare, ebbero con la città di Urbino e la corte ducale. Lo spoglio sistematico di una vasta tipologia di “instrumenta” notarili del XV e XVI secolo, conservati presso l’Archivio di Stato di Urbino, ha permesso non solo la ricostruzione genealogica dei Santi dalle origini fino alla sua estinzione (secoli XV-XVI), ma anche l’inquadramento storico di tutti quei nuclei parentali di spicco (ad esempio i Ciarla, gli Zaccagna, i di Parte, i Vagnini, i Buffa, i Baldi, i Bramante), finora poco o per nulla conosciuti, che ebbero un ruolo fondamentale anche nella vita di Raffaello e nei suoi contatti con la città d’origine.
Costante è stato, poi, l’orientamento metodologico e critico verso una larga lettura di testimonianze coeve, al momento studiate solo marginalmente, come i corposi manoscritti dell’Archivio della Curia Arcivescovile di Urbino insieme ai volumi della Confraternita del “Corpus Domini” e a quelli della Fraternita di Santa Maria della Misericordia, istituzioni di spicco della città urbinate e intimamente partecipi alle vicissitudini patrimoniali dei Santi.
Dagli archivi urbinati sono quindi emersi nuovi documenti, che hanno consentito di approfondire la posizione sociale in vista e l’agiatezza economica di Casa Santi, possidenti di beni sia dentro sia fuori le mura di Urbino, cresciuta al pari di altre casate locali all’ombra della signoria ducale feltresca e roveresca, di cui seguirono di padre in figlio le alterne vicende storiche.
Al saggio introduttivo segue un corposo apparato documentario, a cura di Anna Falcioni e Vincenzo Mosconi, contenente regesti e trascrizioni di 512 documenti per la maggior parte inediti
Falcioni L, Gallotta MC, Baldari C, Cardinali L, Campanella M, Ferrari D, Guidetti L, Meucci M. Influence of training status on cardiac and vascular functioning in young recreational and competitive male rowers. Frontiers in Pediatrics, section Pediatric Cardiology
No full textIntroduction: The aim of the study was to investigate the influence of training
status on cardiovascular function in young male recreational and competitive
rowers.
Methods: Ejection duration in percentage to the heart rate period (ED%),
subendocardial viability ratio (SEVR), augmentation index at 75 bpm (AIx75) and
carotid to femoral pulse wave velocity (cf-PWV) of competitive rowers (CR) (age
17.6 ± 4.1 years), recreational rowers (RR) (age 16.7 ± 2.70 years) and athletes
practicing other recreational sports (ORS) (age 15.3 ± 1.4 years) were assessed.
Results: ED% was lower in CR compared to ORS (31.9 ± 3.9% vs. 38.4 ± 4.8%; p =
0.026) and cf-PWV was higher in CR compared to ORS (5.5 ± 1.0 m/s vs. 4.7 ±
0.5 m/s; p = 0.032). SEVR was higher in CR compared to RR and ORS (165.8 ±
33.7% vs. 127.4 ± 30.4% and 128.3 ± 27.8%; p = 0.022) and AIx75 was lower in CR
compared to RR and ORS (−15.7 ± 8.6% vs. 1.2 ± 9.9% and 1.5 ± 9.1; p = 0.001).
Discussion: Healthy, young competitive male rowers reported higher myocardial
performance and better cardiovascular health than recreational athletes.
Interpretations of cf-PWV in competitive rowers should be performed alongside
other cardiovascular indicators
Scheda critica, in Gentile da Fabriano e l’altro Rinascimento, a cura di L. Laureati-L. Mochi Onori Milano, Electa, 2006
No full textGentile da Fabriano e l’altro Rinascimento, a cura di C. Christiansen, A. De Marchi, L. Laureati, L. Mochi Onori
No full textHa collaborato, come responsabile scientifico, alla sezione documentaria della mostr
Antioxidant activity of wheat sprouts extract in vitro: inhibition of DNA oxidative damage
No full textab
Intracranial facial nerve grafting after removal of vestibular schwannoma
No full textAm J Otolaryngol. 2009 Mar-Apr;30(2):83-8. Epub 2008 Jul 22.
Intracranial facial nerve grafting after removal of vestibular schwannoma.
Bacciu A, Falcioni M, Pasanisi E, Di Lella F, Lauda L, Flanagan S, Sanna M.
SourceDepartment of Otolaryngology, University of Parma, Parma, Italy. [email protected]
Abstract
OBJECTIVE: The objectives of this study were to evaluate outcomes from facial nerve (FN) cable grafting in patients who experienced FN transection during vestibular schwannoma removal and to compare the FN outcomes of patients who underwent FN grafting by using fibrin glue with those of patients who underwent FN grafting by using microsuture.
MATERIAL AND METHODS: We retrospectively evaluated a series of 33 patients in whom FN grafting was achieved either by using microsuture (8 cases) or fibrin glue (25 cases). Immediate repair of the FN was performed in all cases at the time of initial resection. The patients FN function was assessed preoperatively, in the immediate postoperative period, and at 3, 6, 9, and 12 months or more postoperatively using the House-Brackmann grading system. All patients had at least 1-year follow-up.
RESULTS: At 12 months, a House-Brackmann grade III was achieved in 75% of those who underwent cable nerve graft interposition by using microsuture and in 76% of those who underwent cable nerve graft interposition by using fibrin glue. Analysis of final FN function outcomes demonstrated no statistically significant difference in FN outcomes between the 2 groups (P = .891, Mann-Whitney U test; P = .1, Fisher exact test).
CONCLUSIONS: The functional results after FN cable grafting by using fibrin glue exclusively were equivalent to those obtained with microsuture. However, the technique of FN repair by means of fibrin glue is technically simple, less time-consuming, and imparts less trauma on the nerve than does the traditional suture method
Interaction of tributyltin(IV) chloride and related [Bu3 Sn(LSM)] complex with rat leukocytes and erythrocytes: effect on DNA and on plasma membrane
No full textThe discovery of the antitumor activity of cisplatin led several research groups to investigate the possible
therapeutic applications of othermetal-based compounds. Organotin(IV) complexes have been developed
from organotin compounds that were employed in industry and agriculture as stabilizers and pesticides,
respectively. A careful choice of the ligand coordinated to an organotin(IV) fragment can modulate the
activity of the organotin(IV) complex and minimize its drawbacks.With this aim, the tributyltin(IV) complex
[Bu3Sn(LSM)] (LSM= bis(1-methyl-1H-imidazol-2-ylthio)acetate) was synthesized and its in vitro
effects on rat blood cells were compared with those of the analogous tributyltin(IV) compound without
the anionic ligand.
Comet-assay results show that both the tributyltin(IV) chloride (TBTC) and the complex [Bu3Sn(LSM)]
can induce DNA damage in leukocytes, but a stronger effect was observed in the presence of the organotin(
IV) complex. Moreover, lipid-hydroperoxide formation in leukocyte plasma membranes increases
more in the presence of [Bu3Sn(LSM)] compared with TBTC, while TBTC can change the lipid order and
packing of leukocytes and, partially, erythrocyte plasma membranes. The treatment of whole blood with
these two compounds shows a preferential oxidative effect of TBTC on erythrocyte plasma membranes
and erythrocyte oxidative processes, which influence the induction of DNA damage in leukocytes. The
different hydrophobic characters and the different extents of steric hindrance of TBTC and [Bu3Sn(LSM)]
influence the capacity of the two compounds to cross the plasma membrane and affect the pathways that
lead to DNA damage
Initial growth of Boltzmann entropy and chaos in a large assembly of weakly interacting systems
No full text15 pages.-- PACS numbers: 05.45.−a; 05.60.−k; 05.45.Jn.-- Final full-text version of the paper available at: http://dx.doi.org/10.1016/j.physa.2007.06.036.We introduce a high-dimensional symplectic map, modeling a large system, to analyze the interplay between single-particle chaotic dynamics and particles interactions in thermodynamic systems. We study the initial growth of the Boltzmann entropy, SB, as a function of the coarse-graining resolution (the late stage of the evolution is trivial, as the system is subjected to no external drivings). We show that a characteristic scale emerges, and that the behavior of SB vs t, at variance with the Gibbs entropy, does not depend on the resolution, as far as it is finer than this scale. The interaction among particles is crucial to achieve this result, while the rate of entropy growth, in its early stage, depends essentially on the single-particle chaotic dynamics. It is possible to interpret the basic features of the dynamics in terms of a suitable Markov approximation
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