1,720,970 research outputs found

    Sport per disabili: dalla riabilitazione alle Paralimpiadi.

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    La pratica regolare di esercizio fisico, cioè di attività motoria strutturata determina in soggetti con disabilità locomotoria, ed in particolare in soggetti con mielolesione (tetraplegici e paraplegici), effetti benefici sulla salute. Tali effetti salutari consistono nel miglioramento dell’efficienza cardiovascolare e respiratoria (con un ridotto rischio di incorrere in malattie conseguenti all’aterosclerosi), miglioramento della “fitness” muscolare (forza massima e capacità di protrarre l’esercizio a differenti livelli di contrazione sottomassimale) ed un generale miglioramento della funzionalità motoria con conseguente maggiore autonomia e ridotto stress cardiocircolatorio nelle attività della vita quotidiana. Dagli anni ‘70 in poi, parallelamente al suo uso di tipo fisiatrico, lo sport per i soggetti disabili si è andato sempre più evolvendo, acquistando popolarità e valenza agonistica sempre maggiore tanto da potersi ora considerare, in termini di spettacolo e di significato sociale, alla stessa stregua dello sport per i normodotati. Oggi le Paralimpiadi estive sono considerate per importanza il secondo evento sportivo al mondo (www.paralympic.org). Poichè la pratica sportiva non è però esente da rischi è fondamentale una accurata valutazione dello stato di salute degli atleti che raggiungono l'obbiettivo di gareggiare a livello paralimpico. sulla base di una ventennale esperienza iniziata con le visite paralimpiche di Seoul ‘88, frutto di una collaborazione tra la Scuola di Specializzazione in Medicina dello Sport dell’Università di Roma “Sapienza”, diretta dal Prof. Marco Marchetti, e la allora Federazione Italiana Sport Handicap, è stata messa a punto la visita di idoneità paralimpica

    Intensity And Energy Expenditure Of Sports In Elite Paralympic Athletes With Locomotor Disabilities

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    Symposium Lessons Learned on the Road to Vancouver (Olympic and Paralympic Friday 3:15PM-5:15PM Andrew Pipe,FACSM,University of Ottawa Sports Medicine Issues Committee) Heart Institute Randall L.Wilber,FACSM,United States Olympic Committee Jos de Koning,FACSM,University of Amsterdam Donald McKenzie,University of British Columbia Mark Aubry,Ottawa Sport Medicine Centre Marco Bernardi,University of Rom

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Buckypaper as absorbable adhesive for surgical applications

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    FONANZIAMENTO pROGETTO DI RICERCA INTERFACOLTA' dIP pARIDE sTEFANINI Chirurgia Generale e Dip di Chimica Anno 2010 prot C26A10HCNR per 5333€ di 35000€TOPICS: Biotecnologia ed innovazioni tecnologiche. Le proposte italiane nella ricerca. BUCKYPAPER AS ABSORBABLE ADHESIVE FOR SURGICAL APPLICATIONS Massimo Chiaretti(1), Andrea Martinelli(2), Giovanna Angela Carru(3), Fabio Procacciante(1), Lucio D’Ilario(2), Emanuela D’Amore(4), Alessandra Maria Chiaretti(5), Fabio Faiola(6) and Paola Consentino(7). (1)Department of General Surgery “Paride Stefanini”, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161 (Italy) (2)Department of Chemistry, Sapienza University of Rome, P.le Aldo Moro 5, Rome, 00185 (Italy) (3)Policlinico Umberto I Hospital, Sapienza University of Rome, Viale del Policlinico 155, 00161 - Rome (Italy) (4)National Health Institute, Viale Regina Elena 299, 00161 - Rome (Italy) (5)Biologic Sciences Faculty, University of Rome, P.le Aldo Moro 5, Rome, 00185 (Italy) (6)Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, Rome, 00161 (Italy) (7)Appialab Srl V. Latina, 286 00179 Rome (+39) 067825111www.appialab.it E-mail: [email protected] Keywords: buckypaper, carbon nanotubes, medical application, abdominal surgery, wet adhesion absorbable adhesive device. Introduction: The adhesion of a surface on a biological tissue represents an important scientific and technological issue which excites the interest of many researchers. One of the main problems related to the abdominal prosthetic surgery is the mesh fixation. On the one hand suture line tension, mesh separation or displacement, improper and blind application of metal tacks and staples in laparoscopy surgery are the main causes of complications, including seroma, postoperative pain and recurrence[6-9]. On the other hand, the use of human fibrin as glue between the prosthesis and the damaged tissue, although it has become a well-established surgical procedure, presents possible risks associated to the transmission of unknown diseases related to the use of human blood-derived materials [9]. Moreover, it was observed that an increased incidence of postoperative seroma is associated to the use of fibrin glue for mesh fixation[10]. Surfaces able to adhere promptly and strongly on wet biological tissue may represent an effective alternative to the conventional prosthesis fixation methods. This study proposes the application of the nature inspired micro- or nano-patterned adhesive surfaces, by exploiting the scaling effect, according to which the adhesion strength can be enhanced through the reduction of interface adhesive contact size. We experimented evidences on the potential applicability on wet biological tissue of the Buckypaper (BP) as an adhesive tape: BP is a self-standing felt composed of entangled multi-walled carbon nanotubes. In vitro bench surgery mechanical peeling and shear adhesion tests and In vivo tests If compared to other commercial tested prosthesis meshes, BP shows a stronger adhesion, only on wet tissues. much better than both self-gripping commercial mesh and fibrin-glue non-gripping meshes and fabrics. Prompted by these results, we implanted BP in rabbits, to assess its effectiveness as adhesive absorbable prosthetic device and its biocompatibility. After 35 days from the operation we observed that no rabbit behavioral alteration occurred; the BP samples preserved their position in the implantation site and mechanical adhesion was enhanced. This is indicative of no toxicity, good integration and slow reabsorption of the synthetic material into the surrounding tissue without eliciting adverse reactions. Materials and Methods. Operated New Zeeland 3000g female rabbits (R1-R4) did not show mortality or morbidity, no significant neurovegetative or behavioral differences in comparison with the no operated control R5. Results and Discussion. Body weight monitoring graph do not showed any significant difference. The Hematoxilin and Eeosin (H&E) stained implant section reported BP surface fragmentation, shows the formation of a capsule of loose fibrous tissue, consisting of fibroblasts and collagen fibers, indicative of a weak inflammation reaction., the necroscopy examination of R2 showed that the implanted PP favors a cicatrisation process, the mesh appearing wrapped in the inflammatory reaction. In R4, the no sutured incision, tighten by the BP strep, was normally closed and healed. On the smooth BP surface facing the abdominal cavity, explanted from R3, a scarcely adherent neo-formed protein fibrous carpet, about 5 mm thick, may be observed in scansion electronic microscope (SEM). Conclusions: by peeling and shear mechanical tests, a strong BP adhesion on wet biological tissue was measured. In view of a possible application as adhesive absorbable tape in surgery, preliminary in vivo experiments were carried out on rabbit model. Necroscopical and histological investigations enlighten that 35 days after the implantation, the BP elicits minimal adverse tissue response, and when exposed to the peritoneal cavity, no adhesion of omentum or intestinal loops was observed. Nanometric carbon nanotube aggregates, deriving from the surface BP fragmentation, were phagocytised by macrophages and observed in Bowman's urinary space. The assessment of the BP debris, possible toxicity or confinement or metabolism and accumulation or excretion mechanism needs further studies. However, we believe that the results here reported can be used to propose the BP as a new wet absorbable adhesive tape to fix prosthetic materials. References 1. L. Liu, W. Ma, Z. Zhang,Small 2011, 7, 1504 2. M. Chiaretti, G. Mazzanti, S. Bosco, S. Bellucci, A. Cucina, F. Le Foche, G. A. Carru, S. Mastrangelo, A. Di Sotto, R. Masciangelo, A. M. Chiaretti, C. Balasubramanian, G. De Bellis, F. Micciulla, N. Porta, G. Deriu, A. Tiberia, J. Phys.: Condens. Matter 2008,20, 474203 3. A. Di Sotto, M. Chiaretti, G. A. Carru, S. Bellucci, G. Mazzanti, Toxicol. Lett. 2009, 184, 192 4. S. Bellucci, M. Chiaretti, A. Cucina, G.A. Carru,A.I. Chiaretti, Nanomedicine 2009, 4, 531 5. a) The mean equivalent radius was evaluated by wicking tests carried out in water, assuming a water contact angle of about 80°; b) G. Callegari, I. Tyomkin, K. G. Kornev, A.V. Neimark, Y-L. Hsieh, J. Colloid Interface Sci.2011, 353, 290 6. B. P. Jacob, N. J. Hogle, E. Durak, T. Kim, D. L. Fowler, Surg. Endosc. 2007, 21, 629 7. J. R. Eriksen, J. I. Bech, D. Linnemann, J. Rosemberg, Hernia 2008, 12, 483 8. W. B. Gaertner, M. E. Bonsack, J. P. Delaney, Hernia 2010, 14, 375 9. S. Olmi, A. Addis, C. Domeneghini, A. Scaini, E. Croce, Hernia. 2007, 11, 211 10. S. Bellucci, M. Chiaretti, P. Onorato,F. Rossella, M. S. Grandi, P. Galinetto, I. Sacco,F. Micciulla, Nanomedicine 2010, 5, 209 11. massimochiaretti.wordpress.co

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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