330 research outputs found
Immunosuppressive treatment and radiotherapy in kidney transplant patients: A systematic review
No full textBACKGROUND Immunosuppression (IS) therapy may contribute to cancer development. Some authors have proposed to reduce immunosuppression drugs dose in case of viral infections, in immunosuppression-related diseases, and in patients undergoing radiotherapy. The present analysis reports the results of a systematic review on kidney transplant recipients undergoing immunosuppression and radiotherapy. AIM To define if it is necessary reduce immunosuppression drugs during radiotherapy. METHODS The literature search was based on three electronic databases (Pubmed, Scopus, and Web of Science) using selected keywords linked through the "AND " and "OR " Boolean operators to build specific strings for each electronic search engine. Two researchers independently screened the citations, and disagreement was resolved by discussion or through the intervention of a third author. The review was conducted and reported according to the PRISMA statement. Extracted data were narratively synthesized, and, where possible, frequencies, percentages, and ranges were calculated. RESULTS The literature search resulted in 147 citations. After abstracts screening, 21 records were selected for full-text evaluation. Fifteen of these were excluded, leaving six papers considered suitable for analysis. There is still no clear evidence that withdrawing antimetabolites and/or calcineurin inhibitors and/or mammalian target of rapamycin-inhibitors, as opposed to continuing maintenance IS, improves patient survival in kidney transplant recipients with cancer undergoing radiotherapy. Only few retrospective studies on small cancer patient cohorts are available in this setting, but without comparison of different immunosuppression treatments. Even where immunosuppression therapy was described, patient survival seemed to be correlated only with cancer stage and type. CONCLUSION The results of this systematic review do not support the reduction of immunosuppression dose in patients undergoing radiotherapy
Publisher Correction: Unveiling the strong interaction among hadrons at the LHC (Nature, (2020), 588, 7837, (232-238), 10.1038/s41586-020-3001-6)
No full textIn Fig. 1c of this Article, owing to an error during the production process, the equation incorrectly began ‘C(k*, r*) = …’ instead of ‘C(k*) = …’. In addition, in affiliation 71 ‘Dipartimento di Fisica dell’Università degli studi di Bari Aldo Moro’ has been corrected to read ‘Dipartimento di Fisica dell’Università degli studi di Cagliari’. The original Article has been corrected online. *A list of authors and their affiliations appears online. © 2021, The Author(s), under exclusive licence to Springer Nature Limited
Neutral pion production at midrapidity in pp and Pb–Pb collisions at √ sNN TeV
No full textInvariant yields of neutral pions at midrapidity in the transverse momentum range (Formula presented.)c measured in Pb–Pb collisions at (Formula presented.) TeV are presented for six centrality classes. The pp reference spectrum was measured in the range (Formula presented.)c at the same center-of-mass energy. The nuclear modification factor, (Formula presented.), shows a suppression of neutral pions in central Pb–Pb collisions by a factor of up to about (Formula presented.) for (Formula presented.) ≲(Formula presented.)c. The presented measurements are compared with results at lower center-of-mass energies and with theoretical calculations. © 2014, The Author(s)
Publisher Correction: Direct observation of the dead-cone effect in quantum chromodynamics (Nature, (2022), 605, 7910, (440-446), 10.1038/s41586-022-04572-w)
No full textIn the version of this article initially published, there was a typographical error in the first sentence following the “Exposing the dead cone” heading, now reading, “The measurements of R(θ), in the three radiator (charmquark) energy intervals 5 < ERadiator < 10 GeV, 10 < ERadiator < 20 GeV and 20 < ERadiator < 35 GeV…,” where “35 GeV” initially appeared as “3 GeV.” The error has been corrected in the HTML and PDF versions of the article. *A list of authors and their affiliations appears online. © The Author(s) 2022
Coherent ρ0 photoproduction in ultra-peripheral Pb-Pb collisions at √sNN=2.76 TeV
No full textWe report the first measurement at the LHC of coherent photoproduction of ρ0 mesons in ultra-peripheral Pb-Pb collisions. The invariant mass and transverse momentum distributions for ρ0 production are studied in the π+π− decay channel at mid-rapidity. The production cross section in the rapidity range |y| < 0.5 is found to be dσ/dy = 425 ± 10(stat.)− 50 + 42 (sys.) mb. Coherent ρ0 production is studied with and without requirement of nuclear breakup, and the fractional yields for various breakup scenarios are presented. The results are compared with those from lower energies and with model predictions. © 2015, The Author(s)
H-3(Lambda) and (3)((Lambda)over-bar)(H)over-bar lifetime measurement in Pb-Pb collisions at root s(NN)=5.02 TeV via two-body decay
No full textAn improved value for the lifetime of the (anti-)hypertriton has been obtained using the data sample of Pb-Pb collisions at root s(NN) = 5.02 TeV collected by the ALICE experiment at the LHC. The (anti-)hypertriton has been reconstructed via its charged two-body mesonic decay channel and the lifetime has been determined from an exponential fit to the dN/d(ct) spectrum. The measured value, tau = 242(-38)(+34) (stat.) +/- 17 (syst.) ps, is compatible with representative theoretical predictions, thus contributing to the solution of the longstanding hypertriton lifetime puzzle. (C) 2019 The Author. Published by Elsevier B.V
Measuring (KSK +/-)-K-0 interactions using Pb-Pb collisions at root S-NN=2.76 TeV
No full textWe present the first ever measurements of femtoscopic correlations between the K-S(0) and K-+/- particles. The analysis was performed on the data from Pb-Pb collisions at root S-NN = 2.76 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding via the a(0)(980) resonance. The extracted kaon source radius and correlation strength parameters for (KSK-)-K-0 are found to be equal within the experimental uncertainties to those for (KSK+)-K-0. Comparing the results of the present study with those from published identical-kaon femtoscopic studies by ALICE, mass and coupling parameters for the a(0) resonance are tested. Our results are also compatible with the interpretation of the a(0) having a tetraquark structure instead of that of a diquark. (c) 2017 The Author. Published by Elsevier B.V
Measurement of the production of high-p(T) electrons from heavy-flavour hadron decays in Pb-Pb collisions at root s(NN)=2.76 TeV
No full textElectrons from heavy-flavour hadron decays (charm and beauty) were measured with the ALICE detector in Pb-Pb collisions at a centre-of-mass of energy root s(NN) = 2.76 TeV. The transverse momentum (pT) differential production yields at mid-rapidity were used to calculate the nuclear modification factor R-AA in the interval 3 < p(T) < 18 GeV/c. The R-AA shows a strong suppression compared to binary scaling of pp collisions at the same energy (up to a factor of 4) in the 10% most central Pb-Pb collisions. There is a centrality trend of suppression, and a weaker suppression (down to a factor of 2) in semi-peripheral (50-80%) collisions is observed. The suppression of electrons in this broad p(T) interval indicates that both charm and beauty quarks lose energy when they traverse the hot medium formed in Pb-Pb collisions at LHC. (C) 2017 The Author. Published by Elsevier B.V
Measurement of non-prompt D -meson elliptic flow in Pb–Pb collisions at √sNN=5.02 TeV
No full textThe elliptic flow (v2) of D mesons from beauty-hadron decays (non-prompt D) was measured in midcentral (30–50%) Pb–Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02 TeV with the ALICE detector at the LHC. The D mesons were reconstructed at midrapidity (| y| < 0.8) from their hadronic decay D → K -π + , in the transverse momentum interval 2 < pT< 12 GeV/c. The result indicates a positive v2 for non-prompt D mesons with a significance of 2.7 σ . The non-prompt D -meson v2 is lower than that of prompt non-strange D mesons with 3.2 σ significance in 2<pT<8GeV/c , and compatible with the v2 of beauty-decay electrons. Theoretical calculations of beauty-quark transport in a hydrodynamically expanding medium describe the measurement within uncertainties. © 2023, The Author(s)
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