1,503 research outputs found
A espessura da existência humana: Perdas & Ganhos na obra de Lya Luft
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em LiteraturaO estudo enfoca a obra de Lya Luft, especialmente Perdas & Ganhos que causou controvérsias no meio literário por sua dificuldade de classificação. É mapeada a trajetória da escritora desde os seus primeiros escritos na década de 1970. Observa-se que a escritora retoma nos últimos anos os textos curtos # crônicas e ensaios - que também foram o começo de sua vida literária. As crônicas publicadas em revista semanal e as comunidades de fãs do sítio de relacionamentos da internet Orkut também são abordadas. Autores contemporâneos das áreas de literatura e ciências humanas subsidiam teoricamente o estudo para entender como o sucesso dos temas recorrentes e dos livros da escritora são parte do modus vivendi no atual estágio da sociedade capitalista. Com Perdas e Ganhos, Lya Luft deixou de ser reconhecida apenas pelo meio literário, para ser também referência do grande público no Brasil e até no exterior. A despeito disso, no entanto, a crítica que a havia consagrado pelos romances da década de 1980, passou a adotar uma postura de ressalva em relação a escritora, como se tornar-se uma campeã de vendas a desmerecessem. The research is about Lya Luft, especially her book Perdas e Ganhos, who has caused controversy in the Brazilian literature area due to the difficult of classification. We try to understand it, with the study of all the production of Lya Luft, since the first one in the 1970´s. We can see that the author goes back to the same kind of writing that she used in the beginning of her literature life: chronicle and essay. Therefore, we study also the chronicles that Luft is publishing in a Brazilian magazine, and the communities made of Luft´s fans in the relationship site of the Internet, the Orkut. Current names in the literature and human science gave the theoretical instrument to understand how the success of the themes and the books are part of the same modus vivendi of this moment in the life of the society. With the successful of Perdas e Ganhos, Lya Luft are recognition not only by the literature community, but, by the big public in Brazil and other countries too. On the other hand, however, the critics who had applauded her novels in the 1980#s started to have a wondering about the author, because if she is a best seller, she couldn´t be a good writer
Corrigendum: Planning for livelihoods under hydrosocial uncertainty in periurban Pune(Front. Water, (2022), 4, (831464), 10.3389/frwa.2022.831464)
No full textIn the published article, there was an error in the author list, and authors “Sharlene L. Gomes, Shreya Chakraborty, and Leon M. Hermans” were erroneously excluded. The corrected author list appears below. “Sarah Luft Faculty of Mathematics and Natural Sciences, Institute for Geography, University of Cologne, Cologne, Germany Sharlene L. Gomes Faculty of Governance and Global Affairs, Institute of Public Administration, Leiden University, The Hague, Netherlands Shreya Chakraborty South Asia Consortium for Interdisciplinary Water Resources Studies, Hyderabad, India Leon M. Hermans Faculty of Technology, Policy, and Management, Delft University of Technology, Delft, Netherlands and Land andWaterManagement Department, IHE Delft Institute forWater Education, Delft, Netherlands.Policy Analysi
Bilateral and unilateral arm training improve motor function through differing neuroplastic mechanisms: a single-blinded randomized controlled trial
No full textBACKGROUND AND PURPOSE:
This randomized controlled trial tests the efficacy of bilateral arm training with rhythmic auditory cueing (BATRAC) versus dose-matched therapeutic exercises (DMTEs) on upper-extremity (UE) function in stroke survivors and uses functional magnetic resonance imaging (fMRI) to examine effects on cortical reorganization.
METHODS:
A total of 111 adults with chronic UE paresis were randomized to 6 weeks (3×/week) of BATRAC or DMTE. Primary end points of UE assessments of Fugl-Meyer UE Test (FM) and modified Wolf Motor Function Test Time (WT) were performed 6 weeks prior to and at baseline, after training, and 4 months later. Pretraining and posttraining, fMRI for UE movement was evaluated in 17 BATRAC and 21 DMTE participants.
RESULTS:
The improvements in UE function (BATRAC: FM Δ = 1.1 + 0.5, P = .03; WT Δ = -2.6 + 0.8, P < .00; DMTE: FM Δ = 1.9 + 0.4, P < .00; WT Δ = -1.6 + 0.7; P = .04) were comparable between groups and retained after 4 months. Satisfaction was higher after BATRAC than DMTE (P = .003). BATRAC led to significantly higher increase in activation in ipsilesional precentral, anterior cingulate and postcentral gyri, and supplementary motor area and contralesional superior frontal gyrus (P < .05). Activation change in the latter was correlated with improvement in the WMFT (P = .01).
CONCLUSIONS:
BATRAC is not superior to DMTE, but both rehabilitation programs durably improve motor function for individuals with chronic UE hemiparesis and with varied deficit severity. Adaptations in brain activation are greater after BATRAC than DMTE, suggesting that given similar benefits to motor function, these therapies operate through different mechanisms
Adrenergic responsiveness of adipose tissue lipolysis in autonomic failure
No full textThe sympathetic nervous system mobilizes lipids from adipose tissue through stimulation of beta-adrenergic receptors. The increase in lipid supply augments lipid oxidation. Patients with autonomic failure provide a unique opportunity to further elucidate the role of the adrenergic system in adipose tissue metabolism. In 4 patients with severe pure autonomic failure (PAF), in 3 multiple system atrophy patients (MSA), and in 16 healthy young controls, we inserted a microdialysis catheter in abdominal adipose tissue. The catheter was perfused with incremental concentrations of the nonselective beta-adrenoreceptor agonist isoproterenol. Dialysate glucose, lactate, and glycerol were measured to assess glucose supply, glycolysis, and lipolysis, respectively. Basal dialysate glycerol concentrations were 84 +/- 28 microM in PAF and 130 +/- 64 microM in MSA patients. The increase in dialysate glycerol with isoproterenol was identical in PAF and in MSA patients. We found an almost complete overlap in dialysate glycerol concentrations during isoproterenol stimulation between PAF and MSA patients and healthy young control subjects. Our findings suggest that adipose tissue metabolism is remarkably well preserved in patients with chronic sympathetic denervation, both at rest and during local adrenergic stimulation. We propose that beta-adrenoreceptor upregulation is compensated by a desensitization of post receptor mechanisms or by an upregulation of antilipolytic pathways
Did you know? Fluid-and-electrolyte replacement and the uncertainty principle
No full textSurprises are not always welcome. We have studied total body water, quantified the volume and determined the extracellular space, interstitial, and plasma volumes. Nonetheless, estimating these parameters clinically (at the bedside) is frustratingly imprecise. The author ruminates over 50 years clinical experience in intensive care units and grapples with the literature
Dokumente zur Geschichte der Luft- und Raumfahrtforschung in Deutschland 1900-1970
No full textDie Mitteilung ist der begleitende Dokumentband zu dem Buch des Verfassers mit dem Titel: 'Luft- und Raumfahrtforschung in Deutschland 1900-1970. Politische Geschichte einer Wissenschaft'. Campus Verlag, Frankfurt/New York 1992. Sie enthaelt 148 bislang unveroeffentlichte Dokumente zur Geschichte der Luft- und Raumfahrtforschung in ihrem politischen Umfeld. Zeitliche Schwerpunkte bilden das 'Dritte Reich' und die Bundesrepublik Deutschland. Gut die Haelfte der Dokumente stammt aus den Jahren nach dem Zweiten Weltkrieg. (orig.)This note is the accompanying edition of sources to the book of the author entitled: 'Luft- und Raumfahrtforschung in Deutschland 1900-1970. Politische Geschichte einer Wissenschaft'. Published by Campus, Frankfurt/New York 1992. The present note contains 148 unpublished documents on the history of aeronautical and space research in its political context. The main emphasis is put on the era of the 'Third Reich' and the Federal Republic of Germany. More than half of the documents deal with the years after World War Two. (orig.)SIGLEAvailable from TIB Hannover: RN 278(92-08) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
Bound leptin and sympathetic outflow in nonobese men
No full textLeptin exists in a free form and a receptor-bound form. Protein-bound rather than free leptin levels may be associated with regulation of muscle sympathetic nerve activity (MSNA). We determined MSNA and bound leptin concentrations in 25 men [age, 29 +/- 6 yr, body mass index (BMI), 24 +/- 3 kg/m(2)]. Baroreflex sensitivity was measured using phenylephrine and nitroprusside infusions. We measured bound leptin in patients with central (multiple system atrophy, n = 8; age, 59 +/- 8 yr; BMI, 23 +/- 2 kg/m(2)) and peripheral autonomic failure (pure autonomic failure, n = 4; age, 71 +/- 10 yr; BMI, 25 +/- 3 kg/m(2)). MSNA was correlated with protein-bound leptin concentrations (r(2) = 0.35; P < 0.01) but not with free leptin levels (r(2) = 0.09). MSNA at baseline was 15 +/- 2 bursts x minutes(-1) in subjects with lower and 24 +/- 3 bursts x minutes(-1) in subjects with higher bound leptin concentrations (P < 0.05). Blood pressure as well as baroreflex regulation of heart rate and MSNA was similar in both groups. Phenylephrine and nitroprusside responses were similar. Patients with multiple system atrophy and autonomic failure featured similar bound leptin levels. We conclude that protein-bound rather than free leptin levels are correlated with basal sympathetic outflow in normotensive, nonobese men. This relationship cannot be explained by a direct central nervous effect of protein-bound leptin. Instead, protein-bound leptin may increase sympathetic vasomotor tone indirectly via a baroreflex mechanism
- …
