362 research outputs found

    Image de soi et échec scolaire

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    Pierrehumbert Blaise, Zanone F., Kauer-Tchicaloff C., Plancherel Bernard. Image de soi et échec scolaire. In: Bulletin de psychologie, tome 41 n°384, 1988. Recherches en Suisse, en Belgique. pp. 333-345

    Autonomic function and autoantibodies to autonomic nervous structures, glutamic acid decarboxylase and islet tyrosine phosphatase in adolescent patients with IDDM

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    Recent studies have linked autoimmunity to nervous tissue structures and diabetic autonomic neuropathy, but data on the early stage of IDDM and on the natural history of this association are not available. For this reason, we investigated autonomic nervous function, and the presence of autoantibodies to sympathetic and parasympathetic nervous structures, to glutamic acid decarboxylase (GAD) and tyrosine phosphatase (IA-2/ICA512) in 85 adolescents with insulin-dependent diabetes mellitus (IDDM) (mean age 14.7 +/- 1.6 yr, mean duration of diabetes 6.8 +/- 3.5 yr), and 45 age and sex-matched healthy subjects. Nervous tissues autoantibodies were detected using an indirect immunofluorescent complement-fixation technique, with monkey adrenal gland, rabbit cervical ganglia and vagus nerve as substrates. GAD and IA-2/ICA512 autoantibodies were detected by radioimmunoprecipitation assay. Seven patients (8%) had anti-vagus nerve autoantibodies, 7 other patients (8%) had anti-cervical ganglia autoantibodies, while all controls were negative (P < 0.05). Anti-adrenal medulla antibodies were detected in 16 patients (19%) and in 2 control subjects (P < 0.02). None of the patients had autonomic symptoms. When patients were divided according to the presence or absence of autoantibodies, values of the cardiovascular tests (deep breathing, 30:15 ratio, Valsalva ratio) were similar in the two groups and similar to those in healthy subjects. However, when considered together, patients positive for one or more autoantibody showed a trend for lower values of deep breathing test and 30:15 ratio test, compared with healthy control subjects, which failed to reach conventional significance values(P = 0.17 and P = 0.07, respectively). No correlation was found between cardiovascular parameters and metabolic control or diabetes duration. There was no association between autoimmunity to nervous tissue structures acid presence of GAD and IA-2/ICA512 Ab, and no correlation between these two autoantibodies and values of cardiovascular tests. Our data indicate that autonomic dysfunction is not a characteristic of young diabetic patients, but that autoantibodies against autonomic nervous structures are present during the first 1 to 15 yr of diabetes. GAD and tyrosine phosphatase appear to be excluded as target autoantigens within autonomic structures. Follow-up studies are required to evaluate future autonomic dysfunction and symptoms in these patients, and to establish whether the subtle autonomic dysfunction detected and/or the nervous tissue autoantibodies, are predictive of the development of this complication. (C) 1998 Elsevier Science B.V. All rights reserved

    Congratulations to the First Graduating Class

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    Full college status at CBC was abandoned before World War One and not restored until after World War Two. Eight students -- Martin Thomas Burke, Joseph Charles Carbuzinski, Boyd Joseph Lee, Jr., Alexander James Montesi, John Raymong Priora, Raymond Hugh Rolwing, William J. Witte, and Charles F. Zanone --were the first recipients of Bachelors degrees after the college division was reinstated

    Life Span History of Non-fatal Suicidal Behaviours in a Large Sample of General Practitioners' Patients: Data from Rovigo, Northern Italy.

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    A survey about history of non-fatal suicidal behaviour was performed on 1,171 subjects in the waiting room of general practitioners' practices in the territory of Rovigo (Northern Italy). The mean age of interviewed subjects was 52.9 ± 17.0, with a majority of female individuals. Two and two percent admitted previous experience of non-suicidal self-injury, 4.7 % admitted having had serious suicidal thoughts/plans, and 1.8 % reported at least one suicide attempt. Compared to the rest of the sample, people with history of suicidal behaviours resulted to be of younger age (p < .05), whilst their level of well-being was poorer (p < .001). When compared to the results of the Italian arm of the European Study of the Epidemiology of Mental Disorders, carried out on general population samples, the present study produces higher rates of suicidality, despite the much higher mean age of the interviewed subjects compared to the general populatio

    Zanone, Augustina (Death, 1871-06-15)

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    Address: 274 SeventhAge at death: 80Pg 156/1871/224/F W M/Italy/Heart Disease/Dr. J. GarrisonOriginal record filed in drawer labeled &#039;ZABAN-ZIMMENS&#039;
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