27,302 research outputs found
Rossi V., Tripodi F., NIMBI F.M., Simonelli C. (2018). Genital sexual pain in reproductive-age women: an explorative study. 14th Congress of the European Federation of Sexology
Objective: Genital Sexual Pain (GSP) is a common symptom in reproductive-age women. Although this
complaint could negatively affect the quality of sex life, there is still a lack of awareness about it in the female
population. The objective of the present study was to explore the presence of GSP in reproductive-age
women, the characteristics of pain (duration, location, etiology), the way women deal with the symptom, and
their sexual functioning.
Design and Method: 653 women (mean age 25.7±4.37) were recruited with snowball method. Participants
completed a socio-demographic questionnaire, the McGill Pain Questionnaire (MPQ), the Female Sexual
Functioning Index (FSFI), the Female Sexual Distress Scale (FSDS).
Results: 190 women (29.6%) experienced GSP in the last 6 months (mean duration of the symptom
16.87±33.75) located in: vaginal introitus and vestibule (52.1%), lower abdomen/pelvis (44.7%), labia
minora/majora (25.3%), clitoris (8.4%), and perineum/anus (5.3%). Most women (75.3%) did not know the
cause of the pain, and a quarter of them (24.7%) reported a specific diagnosis. 58 out of 190 (30.5%)
considered GSP as a “sexual problem”. 69 (36.31%) and 50 (26.31%) reached clinical scores on FSFI and
FSDS, respectively; only13 (7%) referred to a psycho-sexologist.
Conclusions: GSP was present in almost 30% of women, nevertheless just few of them asked help to a
specialist. There is still a lack of awareness about pain; cultural aspects may lead women to go on with the
symptom increasing the risk of its chronicization and sexuality impairment
"Farmacologia Generale: Risposte abnormi alla somministrazione dei Farmaci - Reazioni idiosincrasiche. 1. Reazioni idiosincrasiche con comparsa di effetti tossici.
Silvaggi M., Todaro E., Rossi V., Aversa F., Rossi R., NIMBI F.M., Simonelli C. (2018). Sexual education and new technologies: the role of social media. 14th Congress of the European Federation of Sexology
Objective: Social Media (SM) and On-line Communities (OC) are increasingly important in youth’s life and
the massive use of these technologies by new generations gave rise to an international debate regarding the
potential effects on relationships and sexuality.
The aim of this paper is to review advantages and limits of SM and OC as ways to build and care
relationships and obtain formal and informal information on sexuality by youth, and moreover as sexual
education programs delivery tools.
Design and Method: A review of scientific literature from January 2007 to May 2017 was performed. The
current review has been based on 77 articles published in Google Scholar, Web of science, Scopus,
PubMed and PsycINFO about the implementation of technology in sexual education programs.
Results: SM platforms such as Short Message Service and Social Networking Sites and OC contribute to
develop adolescent identity, self-expression, intimate relationships and social well-being and to obtain health
information, in particular related to sexuality.
Conclusions: The use of SM and OC among adolescents is not necessarily harmful and could promote a
safer youth sexual behavior and more effective sexual education sessions. Therefore, a critical approach to
SM and OC is needed in order to promote a safe and beneficial use of such tools
Rossi V., Tripodi F., NIMBI F.M., Simonelli C. (2018). Genital sexual pain in reproductive-age women: an explorative study. 14th Congress of the European Federation of Sexology
Objective: Genital Sexual Pain (GSP) is a common symptom in reproductive-age women. Although this
complaint could negatively affect the quality of sex life, there is still a lack of awareness about it in the female
population. The objective of the present study was to explore the presence of GSP in reproductive-age
women, the characteristics of pain (duration, location, etiology), the way women deal with the symptom, and
their sexual functioning.
Design and Method: 653 women (mean age 25.7±4.37) were recruited with snowball method. Participants
completed a socio-demographic questionnaire, the McGill Pain Questionnaire (MPQ), the Female Sexual
Functioning Index (FSFI), the Female Sexual Distress Scale (FSDS).
Results: 190 women (29.6%) experienced GSP in the last 6 months (mean duration of the symptom
16.87±33.75) located in: vaginal introitus and vestibule (52.1%), lower abdomen/pelvis (44.7%), labia
minora/majora (25.3%), clitoris (8.4%), and perineum/anus (5.3%). Most women (75.3%) did not know the
cause of the pain, and a quarter of them (24.7%) reported a specific diagnosis. 58 out of 190 (30.5%)
considered GSP as a “sexual problem”. 69 (36.31%) and 50 (26.31%) reached clinical scores on FSFI and
FSDS, respectively; only13 (7%) referred to a psycho-sexologist.
Conclusions: GSP was present in almost 30% of women, nevertheless just few of them asked help to a
specialist. There is still a lack of awareness about pain; cultural aspects may lead women to go on with the
symptom increasing the risk of its chronicization and sexuality impairment
Once again on Iranian *kund
The current paper is the third treatment by the author (previous ones: Rossi 2002, 2006) of a complex set of terms widely attested in the Iranian area, but also present in Armenian, NW Semitic (and from here Arabic), Indo-Aryan and Dravidian.
Differently from the conclusions of Asatrian/Arakelova paper of 2001, the author identifies three major lexical families, with the following prototypes: (1) *kōnd-/kŏnd- ‘stump, stub’; (2) *kund-/gund- ‘globular, spherical; thick, large, full-bodied’; (3) *kōnd-/kŏnd- (a) ‘stem of a tree, stump, stock’; and secondarily ‘stock of gun, stocks for offenders’; (b) any anatomical articulation conceived as a support (metaphorical projection on human anatomy of a support stick), as ‘kneecap, elbow, knee’.
All of the linguistic families mentioned show interactions between them for all of the three lexical families, and while core semantics are clearly demonstrable for each of them, peripheral (both geographical and semantical) differentiations are widely attested.
Areal atymologies encompassing Indo-Aryan, Iranian and Dravidian are also hinted
Correction: Functionalization of SiC/SiOX nanowires with a porphyrin derivative: A hybrid nanosystem for X-ray induced singlet oxygen generation (Molecular Systems Design and Engineering (2017) DOI: 10.1039/c7me00005g)
The authors regret an error in the name of the 5th author which was incorrectly shown as R. Rossi instead of F. Rossi. The corrected list of authors and affiliations for this paper is shown here. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers
Leptonic decay constants f(K), f(D), and f(Ds) with N-f=2+1+1 twisted-mass lattice QCD
We present a lattice QCD calculation of the pseudoscalar decay constants f(K), f(D) and f(Ds) performed using the gauge configurations produced by the European Twisted Mass Collaboration with N-f = 2 + 1 + 1 dynamical quarks, which include in the sea, besides two light mass degenerate quarks, also the strange and charm quarks with masses close to their values in the real world. The simulations are based on a unitary setup for the two light mass-degenerate quarks and on a mixed action approach for the strange and charm quarks. We use data simulated at three different values of the lattice spacing in the range 0.06-0.09 fm and at pion masses in the range 210-450 MeV. Our main results are f(K+)/f(pi+) = 1.184(16), f(K+) = 154.4(2.0) MeV, which incorporate the leading strong isospin breaking correction due to the up and down quark mass difference, and f(K) = 155.0(1.9) MeV, f(D) = 207.4(3.8) MeV, f(Ds) = 247.2(4.1) MeV, f(Ds)/f(D) = 1.192(22) and (f(Ds)/f(D))/(f(K)/f(pi)) = 1.003(14) obtained in the isospin symmetric limit of QCD. Combined with the experimental measurements of the leptonic decay rates of kaon, pion, D and D-s mesons our results lead to the following determination of the Cabibbo-Kobayashi-Maskawa (CKM) matrix elements: vertical bar V-us vertical bar = 0.2269(29), vertical bar V-cd vertical bar = 0.2221(67) and vertical bar V-cs vertical bar = 1.014(24). Using the latest value of vertical bar V-ud vertical bar from superallowed nuclear beta decays the unitarity of the first row of the CKM matrix is fulfilled at the per mill level
Efficient Lewis Acid Systems for the A3 Coupling reaction
Efficient Lewis Acid Systems for the A3 Coupling reaction
Cimarelli C., a Navazio F.,a Rossi F. V.a, Del Bello F., Marcantoni E.a
aSchool of Science and Technology, Chemistry Division, University of Camerino, Via S. Agostino 1, 62032 Camerino; e-mail: [email protected]
Propargylamines are an attractive class of molecules because of their particular molecular skeleton, that contains an amine group located in β-position to an alkyne moiety suitable for many chemical transformations. In recent years they received a growing interest as key intermediates for several biologically active compound, natural products and also different heterocycles.[1,2]
Our goal was the development of green and simple methodologies for the synthesis of secondary propargylamines by Lewis acid catalyzed or promoted A3 reaction among aldehydes, alkynes and primary amines, that are in general less applied in such reactions because of their lower reactivity. In particular, we studied two different pathway: the CuSO4/NaI system in one pot fashion and the CeCl3/CuI system in one pot/two steps way (Scheme 1).
Scheme 1. CeCl3·7H2O/CuI and CuSO4/NaI catalyzed A3 reaction.
Heptahydrated CeCl3 is reported to be an excellent catalyst for many useful organic transformation as the synthesis of imines. Its efficacy as Lewis acid is enhanced in the presence of inorganic iodides/iodide salt and being cooper the transition metal of choice for A3 reactions, CuI was used.[3]
Also the CuSO4/NaI couple has revealed to be an interesting Lewis acid system as an alternative to CeCl3/CuI system which allow the formation of CuI in situ by quantitative spontaneous reaction that takes place in few seconds.[4]
Typically CuSO4/NaI catalysed reactions are faster than CeCl3·7H2O/CuI reactions, but suffer of some disadvantages, such as lower yields, and a narrower applicability. Both reaction conditions have been applied to different aldehydes (aromatic and aliphatic) and to chiral starting materials, the amine in general has no effect on the reaction outcome.
The relevant Glaser coupling drawback observed in the CuSO4/NaI system conditions has been suppressed by adding some benzoic acid, and has not been observed with the CeCl3/CuI system.
References:
1) Lauder, K.; Toscani, A.; Scalacci, N.; Castagnolo, D. Chem. Rev. 2017, 117, 14091.
2) Peshkov, V. A.; Pereshivko, O. P.; Van der Eycken, E. V. Chem. Soc. Rev. 2012, 41, 3790.
3) G. Bartoli, E. Marcantoni, M. Marcolini, L. Sambri, Chem. Rev. 2010, 110, 6104.
4) Bailey, A. D.; Cherney, S. M.; Anzalone, P. W.; Anderson, E. D.; Ernat, J. J.; Mohan, R. S. Synlett 2006, 215
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