1,835 research outputs found
Epigenomic technologies: an interview with Jorg Tost
No full textInternational audienceJörg Tost received his PhD in genetics from the University of Saarbrücken (Germany) in 2004 for devising novel methods for the analysis of haplotypes and DNA methylation patterns. After a postdoctoral stay in the technology development department of the Centre National de Génotypage (Evry, France), he led the Epigenetics groups from 2006 to 2012, before becoming the Director of Laboratory for Epigenetics and Environment at the Centre National de Recherche en Génomique Humaine (CNRGH). The laboratory is involved in the development and application of technologies to analyze DNA methylation, miRNAs and other epigenetic modifications quantitatively at high resolution at target loci and genome-wide using state-of-the-art sequencing technologies as well as the development of bioinformatic tools for the processing of such data. The laboratory mainly focuses on the analysis of epigenetic changes in neurodegenerative, autoimmune and inflammatory diseases as well as the alteration of the epigenetic profiles in function of environmental exposure. A second research axis investigates novel technologies for the analysis of mutations of clinical relevance present at very low proportions in the analyzed samples and their impact on treatment management. Tost has an H-index of 50 and is the author or co-author of more than 195 publications
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From Mountain to Meadow: The New Realities of Herding in Tost Village
No full textThe video highlights the routine tasks associated with sheep herding in Tost Village, Khar Us. Tost Village serves as a middle summer pasture for herders, allowing them to graze livestock from 20 May to 20 June. However, in recent years, an increasing number of herders have been reluctant to move deeper into the mountains after 20 June, thus reducing their seasonal migration to lower altitudes such as Tost Village throughout the year. Consequently, sheep grazed at lower altitudes during the hot summer months are more prone to insects and diseases, necessitating frequent administration of antiviral medications and regular washing
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Pandemic in the Pastures: Tost Village’s COVID-19 Dilemma
No full textThis video highlights the challenges of COVID-19 testing in Tost Village, Khar Us. The pandemic has triggered frequent and extensive lockdowns across China, significantly impacting remote rural areas. The footage captures herders travelling by car, motorcycle, or horse from their sparse pasturelands to the village centre to receive their COVID test. Despite their isolated living conditions and limited interactions with crowded urban centres, these herders face a heightened risk of virus transmission due to their involvement with frequent testing initiatives. Additionally, indistinctive long periods of lockdowns across the country largely affected herders' everyday tasks related to livestock and farming activities
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Protecting Livestock: Herders’ Struggles with Wild Animals in Tost Village
No full textIn this video, Baajin Bo shares his experience of encountering and hunting wild animals. Baajin Bo was born in Tost village and has lived there his entire life as a herder. Hunting has been a significant part of herders’ lives in the past, not just because they were too poor to rely solely on their prey and domestic livestock, but because hunting itself holds more significance for mobile pastoralists. However, since the Chinese government confiscated all hunting-related tools in the name of protecting wild animals in the 1990s, herders have faced challenges in protecting their livestock from wild animals such as wolves, bears, and even wild boars. Consequently, herders sometimes find ways to catch or scare off wild animals if they attack domestic livestock.
In this video, Baajin Bo shares his experiences of encountering leopards, how they attack and take livestock, and the ways in which herders protect livestock from leopards by keeping a cat at home. Additionally, he discusses local knowledge related to wild boar, lynx, Argali sheep, deer, and wolves
Purolite-Catalyzed Etherification of 2,5-Bis(hydroxymethyl)furan: A Systematic Study
No full textA library of biofuel candidates, 2,5-bis(alkoxymethyl) furans (BAMFs), was prepared from 2,5-bis(hydroxymethyl)furan (BHMF) by etherification in mild conditions using the acid catalyst Purolite. The purification of the BAMFs has been assessed, and gram-scale experiments have been carried out for two specific examples. The efficiency of this synthetic approach to BAMFs was ascribed to the BHMF-activated structure and its interaction with the aromatic acid catalyst
Nota sobre la escama de corrimiento del Montsec de Tost en el Prepirineo español (prov. de Lérida)
No full textEn esta nota se estudian las reacciones tectónicas entre diversas unidades del Prepirineo español (prov. de Lrida), junto a la zona axial pirenaica. El estudio tectnico permite evidenciar el carácter alóctono de la Unidad Montsec de Tost (terminación oriental de la denominada Zona de los Nogueras) y la existencia de dos fases tectónicas perfectamente diferenciadas
Nota sobre la escama de corrimiento del Montsec de Tost en el Prepirineo español (prov. de Lérida)
No full textEn esta nota se estudian las reacciones tectónicas entre diversas unidades del Prepirineo español (prov. de Lrida), junto a la zona axial pirenaica. El estudio tectnico permite evidenciar el carácter alóctono de la Unidad Montsec de Tost (terminación oriental de la denominada Zona de los Nogueras) y la existencia de dos fases tectónicas perfectamente diferenciadas
Optimierte grafische Netzhautbefundung durch softwarebasierte standardisierte Symbolbibliothek
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From Healing to Tourism: A mineral water spring in Tost Village
No full textThis video is about the mineral spring water in Tost village.
The mineral spring water in Khar Us has been famous since the historical times, particularly known to the public for its healing properties, treating various diseases including arthritis, infertility, and many more. However, human intervention has continually disrupted the natural state and the sustainability of water. In 1952, Russians came to Khar Us and installed a wooden mineral bath tank. Later, the Chinese replaced it with an iron tank equipped with an electronic heating system. These changes not only altered the natural spring water and the surrounding environment but also caused the healing properties of the mineral spring water to disappear. As a result, countless tourists, rather than patients, began visiting the place from various locations. Local and wider communities seeking treatment from mineral spring water now have nowhere to go.
In the last ten years, there were climate changes, lack of rains, and constant drought
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