261 research outputs found

    L'invalidità del testamento

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    Al pari dei negozi inter vivos, il testamento è colpito da un giudizio di disvalore da parte dell’ordinamento giuridico, ogni qualvolta l’atto di autonomia privata si discosti, in concreto, dal modello legale. Nondimeno, la sua peculiarità di negozio ad efficacia differita alla morte del suo autore importa che il nostro ordinamento stabilisca regole particolari riguardo alla sua invalidità, al fine di salvaguardare, quanto più possibile, la volontà testamentaria. É, per altro, da osservare, che, nel nostro ordinamento, manca una disciplina organica dell’invalidità del testamento, prevista, invece, per il contratto. Spetta, dunque, all’interprete, tentare un inquadramento sistematico della materia. In proposito, pur negandosi l’applicabilità diretta degli artt. 1418-1446 cod. civ., si ritiene imprescindibile il coordinamento delle norme speciali testamentarie con quelle contrattuali, nei limiti della compatibilità

    Fumonisin B1 metabolism by bovine liver microsomes

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    Only limited and contrasting information is available about the metabolic fate in cattle of fumonisin B1, a mycotoxin produced by moulds of Fusarium. This study was carried out to evaluate the hepatic metabolism of fumonisin B1 by bovine liver microsomes. No biodegradation or metabolization of the mycotoxin by liver microsomes was detectable after incubating fumonisin B1 with bovine microsomes in the presence of a regenerating system for 1 h. No aminopolyol 1, aminopolyol 2 or aminopentol, metabolites of fumonisin B1, were detected in any of the incubated samples. The tolerance of ruminants to fumonisin B1 is apparently not dependent on its detoxification in the rumen

    Aflatoxin B1 binding to sorbents in bovine ruminal fluid

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    A recent approach to the problem of contamination of agricultural products by aflatoxin B1 (AFB1) is to add non-nutritionally adsorbents to animal diets in order to sequester ingested aflatoxins. We conducted in vitro experiments to develop a rapid and cheap model using ruminal fluid to assess the ability of sorbent materials to bind AFB1. Seven sorbents (hydrated sodium calcium aluminosilicate, clinoptilolite, zeolite, two types of bentonite, sepiolite and PHIL 75), commonly added to bovine diet, were incubated in water and ruminal fluid in the presence of AFB1. Hydrated sodium calcium aluminosilicate, sepiolite and one of the bentonites bound 100% of the AFB1 in the presence of both ruminal fluid and water; clinoptilolite bound about 80% of AFB1 in both liquids; whereas the affinities for the mycotoxin of zeolite (50%) and the other sample of bentonite (60%) in water seem to be increased by about 40% in ruminal fluid incubations. PHIL 75 had the poorest binding ability: about 30% in water and 45% in ruminal fluid. In view of the differences in toxin binding in water and ruminal fluid, it is preferable to use the ruminal fluid model for the in vitro pre-screening of sorbent materials potentially useful as adjuvants to ruminant feeds
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