1,720,975 research outputs found
Single-versus multidetector-row CT : comparison of sedation rates, conventional angiograms and motion artefacts in young children following liver transplantation
No full textPURPOSE: The aim of this study was to determine whether the use of multidetector computed tomography (MDCT) is associated with decreased sedation, frequency of motion artefacts and conventional angiograms compared with single-detector CT (SDCT). MATERIALS AND METHODS: CT examinations performed in young children between January 1993 and June 2005 were reviewed retrospectively. Prior to September 2000, SDCT was used; after that period, MDCT was used. The examinations obtained during these two periods were compared for the frequency of sedation, motion artefacts, and conventional angiograms. Statistical comparison between the two groups was determined by using the chi(2) test. RESULTS: A total of 126 infants and children younger than 6 years of age underwent 134 CT examinations. Eighty-eight were obtained with a SDCT (65%) (group 1) and 46 with a MDCT (35%) (group 2). Sedation was required in 31/88 (35%) CT examinations in group 1 and in 6/46 (13%) in group 2. Conventional angiography was performed in 20/88 (22%) cases in group 1 and in 6/46 (13%) in group 2. Motion artefacts were present in 8/88 (9%) CT examinations in group 1 and in 4/46 (8%) in group 2. There was significant statistical difference with regard to sedation and angiography rates between the two groups (p1). CONCLUSIONS: MDCT can reduce the need for sedation and conventional angiography in children after liver transplantation. There is no effect on patient motion artefacts
Prognostic significance of bone marrow histological dysplastic features in essential thrombocythemia
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Plasma cyclic AMP (cAMP), cyclic GMP (cGMP), glucagon (IRG) and atrial natriuretic factor (ANF) levels in liver fibrosis and cirrhosis
No full textUS-elastography in the differential diagnosis of benign and malignant thyroid nodules
No full textUltrasound (US)-elastography is a newly developed imaging technique for the reconstruction of tissue stiffness by measuring the degree of tissue's deformation in response to the application of an external force. This technique has previously been shown to be useful in the differential diagnosis between benign and malignant tumors. METHODS: The objective of this study was to assess the diagnostic accuracy of US-elastography in the differential diagnosis of thyroid cancer, using the cytologic/histopathologic analysis as the reference standard. A total of 67 consecutive patients with thyroid nodules who were referred to the Thyroid Unit at the Policlinico MultiMedica were enrolled in this prospective study between January and December 2006. Eighty-six nodules in these patients were examined by US B-mode, US color-power-Doppler, and US-elastography. Nodules were subjected to fine-needle aspiration biopsy and patients with a reading of malignant or indeterminate had thyroid surgery. The final diagnosis was based on the cytology reading in those who did not have surgery and the histopathology reading in those who had surgery. US-elastography scores were based on four classes of tissue stiffness (class 1 for soft nodules; class 2 and 3 for nodules with an intermediate degree of stiffness; class 4 for anelastic lesions). RESULTS: Seventeen nodules were malignant and 69 were benign. Sensitivity and specificity of the US-elastography for thyroid cancer diagnosis were 94.1% (16/17) and 81% (56/69), respectively. The positive and negative predictive values were 55.2% (16/29) and 98.2% (56/57), respectively. The accuracy of the technique was 83.7%. CONCLUSION: US-elastography is a promising technique that, combined with other US modalities, is easy and rapid to perform and can help to identify thyroid nodules that are likely to be malignant. An important limitation is probably lack of sensitivity for follicular thyroid carcinom
Treatment with hydroxyurea as single agent does not increase the risk of second malignancies in essential thrombocytopenia patients
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
IMMUNOHISTOCHEMICAL EVALUATION OF BONE-MARROW BIOPSIES IN MYELODYSPLASTIC SYNDROMES
No full textImmunohistochemical studies were performed with monoclonal antibodies (MAbs) reactive on paraffin embedded bone marrow biopsies in 19 patients with myelodysplastic syndromes, 8 of them during r-gamma-interferon treatment. CD15 MAbs stained mature myeloid cells predominantly located close to the bone marrow trabeculae. Anti-gpIIIa MAbs permitted precise identification of megakaryocytic cells including precursors and dysplastic megakaryocytes. Labelling with CD45 and CD68 MAbs, recognizing lymphocytes and macrophages respectively, was intense in patients in steady state, but progressively decreased during leukemic transformation. Increase in CD45+ and/or CD68+ cells was also observed in most bone marrow biopsies after 3 months of r-gamma-interferon therapy
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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