1,721,022 research outputs found

    Dialoghi filosofici e scientifici

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    Il volume raccoglie tutti i dialoghi scritti da Leibniz, ad eccezione dei Nouveaux essais sur l'entendement humain. I due dialoghi curati da Gianfranco Mormino, Phoranomus del 1689 e Dialogue effectif del 1695, trattano rispettivamente di dinamica e del problema del male. L'edizione del Phoranomus è stata condotta sul manoscritto originale, conservato a Hannover; il dialogo, scritto durante il viaggio in Italia, mostra l'influenza dello stile compositivo galileiano, impiegato da Leibniz per divulgare ai dotti italiani i progressi compiuti nell'ambito della scienza del moto. Emergono in particolare il tentativo di riformulare le leggi fondamentali della meccanica a partire dal principio della conservazione di mv2 e la prima definizione di una dinamica a priori, poi sviluppata nello scritto Dynamica de potentia. Il Dialogue effectif rientra invece nell'ambito degli scritti sulla teodicea e presenta un originale tentativo di spiegare l'esistenza del male mediante l'analogia con i numeri irrazional

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    «Nos sumus ex Deo et pertinemus ad Deum». Appartenenza, dipendenza e relazione nel pensiero e nel lessico di Arnold Geulincx

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    Abstract Arnold Geulincx attribuisce all’uomo lo statuto ontologico di un quid mentis che assume una dimensione temporale divenendo «mente incorporata», cioè prendendo «forma» attraverso il corpo, definito a sua volta come un «modo» dell’estensione o del corpus simpliciter. Tale incorporarsi di un «qualcosa» di eterno definisce la «condizione umana», caratterizzata perciò dall’appartenenza a «due mondi». Attingendo al pensiero cartesiano, agostiniano e stoico, Geulincx propone un’analisi dello statuto ontologico dell’individuo umano alla luce dell’idea di ‘relazione al tutto’, la quale risulta tuttavia complessa e sfuggente, sia perché declinata diversamente in relazione alla mente e al corpo, sia perché delineata, in polemica col «gergo scolastico», attraverso il ricorso a un lessico insieme misticheggiante (costituito di immagini suggestive) e cartesiano (incentrato sui termini fondativi di sostanza e modo). A partire da tale lessico si propone un’analisi dei concetti di appartenenza, relazione e dipendenza, fondativi dell’intero pensiero di Geulincx

    Rab7 and the CMT2b disease

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    The CMT2B (Charcot-Marie-Tooth type 2B) disease is an autosomal dominant axonal neuropathy. Sensory loss, distal muscle weakness and wasting, frequent foot ulcers and amputations of the toes due to frequent infections characterize this neuropathy. Four missense mutations in the rab7 gene have been identified as causative of the disease. Rab7 is a small G-protein of the Rab family that controls vesicular transport to late endosomes and lysosomes in the endocytic pathway. The CMT2B-associated mutant Rab7 proteins show altered nucleotide dissociation rates and impaired GTPase activity. In addition, these mutant proteins are predominantly in the GTP-bound form when expressed in human cells and they are able to rescue Rab7 function in Rab7-depleted cells. Thus these mutations generate activated forms of Rab7 that are responsible for the development of the disease. In spite of these results, there are still important gaps in our understanding of the mechanism underlying CMT2B. Indeed, how these mutations in the rab7 gene affect specifically peripheral neurons leading to an axonal pathology in CMT2B is not clear, and it is a particularly puzzling and challenging issue in view of the fact that Rab7 is a ubiquitous protein. The present review discusses possible molecular mechanisms underlying CMT2B

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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