61 research outputs found
PROGETTO PUBBLICTO: The view from the rail
Progetto per il concorso di idee bandito dall'Atelier HSL - Oland
Tensile and shear behaviour of an innovative angle bracket for CLT structures
In this paper, experimental tests and numerical analyses conducted on an innovative angle bracket for Cross-Laminated Timber (CLT) structures subjected to tension and shear loads are presented. Such angle bracket represents an improvement of the available angle brackets manufactured by Rotho Blaas and was designed to increase the tensile capacity by adding inclined fully-threaded screws. Results of experimental tests carried out at Laboratory of Earthquake and Dynamic Engineering (LEDA) of the Enna Kore University are presented in terms of force-displacement curves. All the experimental tests are then simulated fusing a numerical model implemented in the FE solver ABAQUS. The influence of the mechanical behaviour of screws and nails on the angle bracket performance was then investigated, considering stiffnesses and strengths from both experimental programmes and codes of practice, and evaluating the importance of the Group Effect. The obtained force-displacement curve is compared with the experimental curves, showing a good accuracy of the proposed FE model. Experimental tests confirmed that fully-threaded screws increased the tensile capacity of the angle bracket. © WCTE 2018 Committee
The FLECS Expandable Module Concept for Future Space Missions and an Overall Description on the Material Validation
Zagros Notes: Gutium and Kakmum
This article is a review of the history of Kakmum, an important polity in the Northwestern Zagros known from the 3rd and 2nd Mill. BC. It demonstrates that a recent suggestion to make Kakmum the capital of Gutium, another important Zagros polity, is probably mistake
L'aquila e il serpente: una lettura giuridica
La Lista Reale Sumerica è un antico documento rinvenuto in vari manoscritti, il più noto dei quali è costituito da un prisma attualmente conservato nell'Ashmolean Museum di Oxford, che elenca tutti i sovrani sumerici, dinastia per dinastia, ponendoli in una sequenza lineare, senza tener conto, cioè, dei sincronismi. La lista si apre con i primi re antidiluviani e prosegue poi fino alle dinastie storicamente attestate, interrompendosi con i primi sovrani di Isin. Dopo il Diluvio, che distrusse tutto, la regalità scese di nuovo sulla terra e si fermò a Kiš. Tra questi primi re è nominato un certo Etana
[Restrospective analysis of the renal biopsy activity in Piedmont]
The Piedmont Group of Clinical Nephrology has compared the activity of 18 nephrology centers in the region Piedmont/Valle d'Aosta with regard to renal biopsy (RB). Data on the RBs performed in every nephrology unit, taking into account their entire experience (in some cases spanning more than 30 years), were analyzed. 3396 RBs were performed between 1996 and 2011. Thirty to forty percent were done in patients aged >-65 years (1568 in patients >-65 years, 29 in patients >-85 years). 598 BRs were performed in children over the last 20 years. The following contraindications to RB were considered: chronic renal failure by 8 centers (44.4%), serum creatinine (SCr >3 mg/dL) by 3 centers, longitudinal renal size 2 mg/dL and 275 in patients on dialysis. The percentage of RBs performed in patients with SCr >2 mg/dL ranged from 27% to 55% between centers. As regards RB in the course of acute renal failure in an ANCA-positive context, 4 centers allowed administration of corticosteroids and 8 centers administration of immunosuppressive treatment as well, even in the absence of histological data. In drug-related nephropathies, RB was considered indicated to confirm the farhypothesis of immunoallergic interstitial nephropathy either if the responsible drug was not among the traditional ones known to induce tubulo-interstitial renal disease or if the pharmacological hypothesis seemed no longer sufficient to justify the renal presentation. All centers but one were against performing RB in case of atheroembolic disease. Three centers performed RB in the intensive care unit. As regards RB in patients undergoing treatment with anticoagulants, aspirin was discontinued 5-14 days before the procedure (mean 8 days) and given again 7-15 days afterwards (mean 11.4 days). Ten centers replaced the anticoagulants with low-dose heparin, which was discontinued the day before the procedure; 11 centers asked advice from cardiologists. RB was repeated in 113 cases after a delay of 1 month to 8 years from the first RB. Our analysis shows uniformity in the approach to RB in this Italian region, with some differences compared with the literature: particular attention was paid to severely critical patients, elderly patients, and patients treated with anticoagulant drugs
Are IgE levels to food other than rosaceae predictive of allergy in lipid transfer protein-hypersensitive patients?
Background: Lipid transfer protein (LTP), the most frequent cause of primary food allergy in Italy, is a cross-reacting plant pan-allergen. Markers able to predict whether a patient sensitized to a certain food but not
yet clinically allergic will develop allergy would be extremely helpful.
Objective: It was the aim of this study to investigate the relevance of IgE levels to some plant foods other than Rosaceae as predictors of either local or systemic allergic reaction in LTP-allergic subjects.
Methods: One hundred (40 males, 60 females , mean age 29 years) peach-allergic patients monosensitized to LTP seen at 14 Italian centres in 2009 were studied. Walnut, hazelnut, peanut, tomato, rice and/or maize allergy was ascertained by interview and confirmed by positive skin prick test. IgE levels to these foods and to rPru p 3 were measured.
Results: Higher levels of IgE to Pru p 3 were associated with a higher prevalence of allergy to hazelnut, peanut and walnut. For all study foods, except rice, median IgE levels in allergic subjects significantly exceeded those in tolerant subjects, though within single allergic groups, the differences between patients reporting systemic or local (oral) symptoms were not significant. Ninety-five percent cut-off IgE levels predictive of clinical allergy were established for study foods although the marked overlaps between allergic and tolerant subjects made them of limited usefulness.
Conclusion: Specific IgE levels are only partially predictive of clinical allergy. The reasons why some individuals showing low specific IgE levels develop clinical allergy whereas others showing high IgE levels do not, despite similar exposure to the allergen, remain unclear
Recovery time after hemodialysis is inversely associated with the ultrafiltration rate.
INTRODUCTION:
The present study aimed to determine the variables that are associated with a longer dialysis recovery time (DRT) and to define the relationship that exists between DRT and the ultrafiltration rate (UFR) in prevalent chronic hemodialysis (CHD) patients.
METHODS:
We studied 210 prevalent CHD of 5 hemodialysis units in Central Italy. Patients were invited to answer to the question: "How long does it take you to recover from a dialysis session?" Answers to this question were subsequently converted into minutes. Demographic, clinical and laboratory parameters were recorded for each patient as well as the UFR (mL/kg/h), the dialysate sodium concentration and temperature.
RESULTS:
Median DRT was 180 min (60-420). Ninety five (45%) patients had a DRT ≥ the median value. Mean UFR was 9.2 ± 3.0 mL/kg/h. Patients with a lower DRT had a less prevalent disability in the instrumental activities daily living, had a higher UFR, and a lower dialysate temperature, as compared with subjects with higher DRT. According to the logistic regression model, UFR was associated with a DRT below the median (i.e., 180) in the unadjusted model (OR 1.12; 95% CI 1.02-1.23; p = 0.019), after adjusting for age and sex (OR 1.11; 95% CI 1.01-1.22; p = 0.025), and in the fully adjusted model (OR 1.11; 95% CI 1.04-1.22; p = 0.040). UFR increase was associated with increasing probability of DRT below the median (p for trend = 0.035). The highest tertile of DRT was associated with UFR below the mean value (i.e., 9.2 mL/kg/h) in multinomial logistic regression having the lowest DRT tertile as reference. DRT was significantly lower in patients with UFR > 13 mL/kg/h than in patients with UFR 10-13 or < 10 mL/kg/h.
CONCLUSION:
DRT is inversely associated with UFR in CHD patients. Whether a high UFR should be recommended to reduce the DRT needs to be elucidated through an adequate prospective randomized study
- …
