1,721,000 research outputs found
Attività antistaminica degli alacaloidi bromopirrolici isolati da poriferi Caraibici appartenenti al genere Agelas
No full textComunicazione poste
Ectyoplasides A-B, Unique Triterpene Oligoglycosides from the Caribbean Sponge Ectyoplasia ferox.
No full textTwo novel norlanostane triglycosides, ectyoplasides A (1) and B (2), have been isolated from the methanolic extracts of the Caribbean sponge Ectyoplasia ferox (Raspaliidae, Axinellida). Their structures have been established by extensive application of high-resolution FABMS and two- dimensional NMR techniques, supported by chemical and enzymatic degradation methods. Ectyoplasides A and B have been shown to possess identical sugar chains (composed of two β-galactose units and one α-arabinose unit), but to differ in their aglycone moieties, which possess nortriterpene skeletons with an unprecedented substitution pattern on ring A. Ectyoplasides A and B show moderate cytotoxic activity when tested in vitro towards various cell lines
Ectyoplasides A-B, Unique Triterpene Oligoglycosides from the Caribbean Sponge Ectyoplasia ferox.
No full textTwo novel norlanostane triglycosides, ectyoplasides A (1) and B (2), have been isolated from the methanolic extracts of the Caribbean sponge Ectyoplasia ferox (Raspaliidae, Axinellida). Their structures have been established by extensive application of high-resolution FABMS and two- dimensional NMR techniques, supported by chemical and enzymatic degradation methods. Ectyoplasides A and B have been shown to possess identical sugar chains (composed of two β-galactose units and one α-arabinose unit), but to differ in their aglycone moieties, which possess nortriterpene skeletons with an unprecedented substitution pattern on ring A. Ectyoplasides A and B show moderate cytotoxic activity when tested in vitro towards various cell lines
Novel bromopyrrole alkaloids from the sponge Agelas dispar
No full textFurther investigation of the Caribbean marine sponge Agelas dispar for biologically active constituents has led to the isolation of the novel bromopyrrole alkaloids longamide B (1), and clathramides C (2) and D (3), whose structures have been determined by spectroscopic methods. Isolation of the known keramadine (4) and of the ecdysonic sterols ecdysterone (5) and ajugasterone C (6) is also reported. The antimicrobial activities of the isolated bromopyrrole alkaloids is summarized
Alcaloidi bromopirrolici bioattivi da quattro spugne Caraibiche del genere Agelas
No full textComunicazione Oral
Attività antibatterica degli alcaloidi bromopirrolici isolati da poriferi appartenenti al genere Agelas.
No full textComunicazione poste
Novel betaines from the marine sponge Agelas dispar
No full textThree novel betaine alkaloids, called Aminozooanemonin (1), Pyridinebetaine A (2) and Pyridinebetaine B (3) have been isolated from the Caribbean sponge Agelas dispar. Their structures were determined by using FABMS, IR, UV, and one- and two dimensional NMR experiments. Aminozooanemonin (1) and pyridinebetaine A (2) showed a moderate antibacterial activity
Longamide and 3,7-dimethylisoguanine, two novel alkaloids from the Marine Sponge Agelas longissima
No full textA purine derivative, 3,7-dimethylisoguanine (1), and a novel alkaloid with the unusual pyrrolopiperazine nucleus, longamide (2), were isolated from the sponge Agelas longissima, and their structures established on the basis of spectroscopic data. In addition, 2 exhibited a mild antibacterial activity
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