1,721,037 research outputs found

    False-positive finding on 18F-FDG PET after chemotherapy for primary diffuse large B-cell lymphoma of the thyroid: A case report

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    Primary non-Hodgkin lymphoma of the thyroid is an uncommon disease. It is a potentially aggressive disease and diffuse large B-cell lymphoma of the thyroid may result in 5 year survival rates <50%. Hence adequate follow-up and multimodality treatment for recurrent or persistent disease are required. Since 18F-FDG PET is considered the imaging method of choice for the detection and staging of lymphoma, this was used for restaging of a case of diffuse large B-cell lymphoma of the thyroid after chemotherapy and its diagnostic value is questioned in the present case report. In fact, PET showed a false-positive finding which led to unnecessary surgery

    Interleukin-2-based therapy following surgery for renal cell carcinoma metastatic to the chest wall.

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    Herein, thè authors report two cases of renai celi carcinoma with solitary metastasis to thè chest wall. lnterleukin-2-based therapy following nephrectomy and resection of thè metastatic lesion of thè chest wall resulted in improvement of quality of life and in prolonged diseasefree survival in ali patients. They believe that an aggressive surgical approach, in selected patients with metastatic renai celi carcinoma, may improve patients' response to immunotherap

    Elective endovascular VS open repair for abdominal aortic aneurysm in patients aged 80 years and older: systematic review and meta-analysis.

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    Endovascular treatment (EVAR) of abdominal aortic aneurysm (AAA) is thought to be of benefit, particularly in patients aged ≥80 years. This issue was investigated in the present meta-analysis. The study design involved a systematic review of the literature and meta-analysis. Systematic review of the literature and meta-analysis of data on elective EVAR vs. open repair of AAA in patients aged ≥80 years were performed. Six observational studies reporting on 13,419 patients were included in the present analysis. Pooled analysis showed higher immediate postoperative mortality after open repair compared with EVAR (risk ratio 3.87, 95% confidence interval (CI) 3.19-4.68; risk difference, 6.2%, 95%CI 5.4-7.0%). The pooled immediate mortality rate after open repair was 8.6%, whereas it was 2.3% after EVAR. Open repair was associated with a significantly higher risk of postoperative cardiac, pulmonary and renal complications. Pooled analysis of three studies showed similar overall survival at 3 years after EVAR and open repair (risk ratio 1.10, 95%CI 0.77-1.57). The results of this meta-analysis suggest that elective EVAR in patients aged ≥80 years is associated with significantly lower immediate postoperative mortality and morbidity than open repair and should be considered the treatment of choice in these fragile patients. These results indicate also that, when EVAR is not feasible, open repair can be performed with acceptable immediate and late survival in patients at high risk of aneurysm rupture

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Diagnostic accuracy of computed tomography in patients with suspected abdominal aortic aneurysm rupture

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    Objectives: This study was planned to evaluate the accuracy of computed tomography angiography (CTA) for suspected rupture of abdominal aortic aneurysm (AAA). Design: Retrospective, observational study. Patients: A total of 97 patients who underwent open aneurysm repair for suspected rupture of AAA. Methods: The accuracy of preoperative and post hoc evaluation of CTA scans was evaluated by using the intra-operative findings as reference. Results: At surgery, 58 patients were found to have a ruptured aneurysm. Interpretation of CTA findings at admission resulted in one false-negative and two false-positive diagnoses of aneurysm rupture as observed at surgery (sensitivity 98.3%, specificity 94.9%, positive predictive value 96.6%, negative predictive value 97.4%). Post hoc, blinded review of CTA findings resulted in one false-negative and three false-positive diagnoses of aneurysm rupture (sensitivity 98.3%, specificity 92.3%, positive predictive value 95.0%, negative predictive value 97.3%). Agreement between initial and post hoc assessment of CTA-findings was statistically significant (kappa 0.978, p < 0.0001). Conclusions: CTA is highly accurate in the diagnosis of suspected rupture of AAA. The risk of false-positive diagnosis is very low and it is not likely to affect the correct analysis of the results of comparative studies on endovascular versus open repair of ruptured AAA.© 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved

    L'adéno-myoepithéliome du sein.Une tumeur à malignité potentielle.

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    L'adéno-myoepithéliome est une néoplasie qui prend origine dans la prolifération simultanée et harmonieuse de cellules épithéliales et myoépitheliales des glandes exocrines. Frèquemment observé au niveau des glandes salivires, l'ad*no-myoepithéliome du sein est une tumeur rare,et pas plus de 60 cas n'en avaient été décrits jusqu'en 1992
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