557 research outputs found

    The effect of melatonin implants on the response to the male effect and on the subsequent cyclicity of Rasa Aragonesa ewes implanted in April. Anim Reprod Sci,

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    Abstract Rasa Aragonesa ewes were used to evaluate whether treatment with melatonin implants in spring could modify: (i) the response to the male effect in terms of oestrous behaviour and ovulation rate; and (ii) the maintenance of sexual activity and ovulation rate at medium term, i.e. over the next 306 days. On 12 April, 42 ewes were divided into two groups, with (M; n = 21) or without (C; n = 21) a subcutaneous implant containing 18 mg melatonin. On 17 May (day 0), three aproned rams were introduced to each group to induce a ram effect. Ewes were observed for oestrus daily. The rams were removed 40 days later after which one aproned ram was introduced daily. Oestrous detection continued until 28 February, 306 days after the first male-female contact. The ovulation rate was determined by endoscopy in the first three cycles after ram introduction and in September-October and January. Progesterone was assayed from blood samples taken on 6 May, 10 and from day 0 to day 22 after ram introduction. Luteal activity before ram introduction was seen in 33% (M) and 29 (C)% of the ewes, respectively. Significantly more M ewes showed oestrous behaviour during the first 40 days after ram introduction (M: 100%; C: 62%; P < 0.01). Similar differences were observed for ewes anovulatory at ram introduction (M: 100%, C: 47%; P < 0.01). These differences were maintained over the three oestrous cycles in both groups. Treatment with melatonin implants was without detrimental effect on cyclic functions in the following breeding season, after seasonal anoestrus. Melatonin treatment significantly increased (P < 0.05) the mean ovulation rate of the first (1.62 ± 0.11 versus 1.31 ± 0.13), second (1.78 ± 0.15 versus 1.36 ± 0.15) and third cycles (M: 1.73 ± 0.12 versus C: 1.27 ± 0.14). There was a significant interaction between the effects of cyclicity at day 0 and melatonin treatment on the ovulation rate in the first cycle (P < 0.05). The mean ovulation rates of both groups were similar at the beginning (September) and middle (January) of the subsequent breeding season. Overall, the results confirmed that melatonin implants, combined with the ram effect, * Corresponding author. Tel.: +34-976-761600; fax: +34-976-761612. E-mail address: [email protected] (F. Forcada). 0378-4320/02/$ -see front matter © 2002 Elsevier Science B.V. All rights reserved. PII: S 0 3 7 8 -4 3 2 0 ( 0 2 ) 0 0 1 1 7 -3 166 O. Zúñiga et al. / Animal Reproduction Science 72 (2002) [165][166][167][168][169][170][171][172][173][174] improved the reproductive parameters of reduced-seasonality ewes during spring mating, without impairing sexual activity or ovulation rate during the subsequent breeding season

    Cross-Amplification and Validation of SNPs Conserved over 44 Million Years between Seals and Dogs

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    Hoffman J, Thorne MAS, McEwing R, Forcada J, Ogden R. Cross-Amplification and Validation of SNPs Conserved over 44 Million Years between Seals and Dogs. PLoS ONE. 2013;8(7): e68365.High-density SNP arrays developed for humans and their companion species provide a rapid and convenient tool for generating SNP data in closely-related non-model organisms, but have not yet been widely applied to phylogenetically divergent taxa. Consequently, we used the CanineHD BeadChip to genotype 24 Antarctic fur seal (Arctocephalus gazella) individuals. Despite seals and dogs having diverged around 44 million years ago, 33,324 out of 173,662 loci (19.2%) could be genotyped, of which 173 were polymorphic and clearly interpretable. Two SNPs were validated using KASP genotyping assays, with the resulting genotypes being 100% concordant with those obtained from the high-density array. Two loci were also confirmed through in silico visualisation after mapping them to the fur seal transcriptome. Polymorphic SNPs were distributed broadly throughout the dog genome and did not differ significantly in proximity to genes from either monomorphic SNPs or those that failed to cross-amplify in seals. However, the nearest genes to polymorphic SNPs were significantly enriched for functional annotations relating to energy metabolism, suggesting a possible bias towards conserved regions of the genome

    The Looner from Barcelona: a Semitics Scholar in Franco Spain 1960-61

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    The Loner from Barcelona: A Semitics Scholar in Franco Spain, 1960–61, de Thomas F. Glick, ofereix un testimoni autobiogràfic de gran valor històric i intel·lectual sobre la seva estada a la Universitat de Barcelona durant el curs 1960-1961, en ple franquisme. El text combina memòria personal i reflexió historiogràfica per reconstruir l’ambient acadèmic, cultural i humà del Departament de Filologia Semítica en un moment clau de lenta represa intel·lectual. Atret per la figura de Josep Maria Millàs Vallicrosa, Glick arribà a Barcelona per formar-se en àrab i hebreu i aprofundir en la història medieval de la ciència, dins el marc de l’“humanisme ampliat” de George Sarton, del qual Millàs fou un dels principals introductors a Espanya. El relat subratlla el paper central de Millàs com a mestre i com a articulador d’una tradició acadèmica que integrava filologia, història de la ciència i estudi comparat de les cultures àrab i hebrea, així com la contribució de figures com Joan Vernet, David Romano i altres membres destacats de l’entorn semitístic barceloní. El text aporta també una dimensió humana especialment rica: l’experiència de Glick com a estudiant estranger, l’aprenentatge del català en un context de fortes limitacions polítiques, els seus recorreguts per la Barcelona històrica i la seva progressiva inserció en xarxes acadèmiques internacionals. Tot plegat s’articula mitjançant la metàfora de la riḥla fī ṭalab al-ʿilm, el viatge a la recerca del coneixement, que situa aquesta etapa com l’inici d’una trajectòria intel·lectual de llarg abast. La presentació, a càrrec de Miquel Forcada, contextualitza l’article dins la historiografia de la història de la ciència i en destaca el valor com a homenatge a la Universitat de Barcelona del tardofranquisme i a una generació d’estudiosos que mantingueren viva la recerca en condicions adverses. El text esdevé així no només una memòria personal, sinó també una contribució rellevant per comprendre la continuïtat i la renovació dels estudis semítics i de la història de la ciència en l’àmbit hispànic.The Loner from Barcelona: A Semitics Scholar in Franco Spain, 1960–61, by Thomas F. Glick, offers a highly valuable autobiographical account of his stay at the University of Barcelona during the academic year 1960–1961, in the midst of the Franco dictatorship. Combining personal memory with historiographical reflection, the text reconstructs the academic, cultural, and human environment of the Department of Semitic Philology at a key moment of cautious intellectual reopening. Drawn to the figure of Josep Maria Millàs Vallicrosa, Glick came to Barcelona to study Arabic and Hebrew and to deepen his interest in the medieval history of science, within the framework of the “expanded humanism” promoted by George Sarton, whose ideas Millàs championed in Spain. The narrative highlights Millàs’s central role as a teacher and as the architect of an academic tradition that integrated philology, history of science, and the comparative study of Arabic and Hebrew cultures, alongside figures such as Joan Vernet, David Romano, and other prominent members of the Barcelona semitistic milieu. The text also provides a rich human dimension: Glick’s experience as a foreign student, his learning of Catalan under restrictive political conditions, his daily itineraries through historic Barcelona, and his early integration into international scholarly networks. These experiences are framed through the metaphor of the riḥla fī ṭalab al-ʿilm, the journey in search of knowledge, which situates this period as the starting point of a long and influential intellectual career. The presentation by Miquel Forcada places the text within the broader historiography of the history of science and underscores its value as a tribute to the University of Barcelona during the late Franco period and to a generation of scholars who sustained rigorous research under adverse conditions. The text thus emerges not only as a personal memoir but also as a significant contribution to understanding the continuity and renewal of Semitic studies and the history of science in the Hispanic world.The Loner from Barcelona: A Semitics Scholar in Franco Spain, 1960–61, de Thomas F. Glick, ofrece un testimonio autobiográfico de gran valor histórico e intelectual sobre su estancia en la Universidad de Barcelona durante el curso 1960-1961, en pleno franquismo. El texto combina memoria personal y reflexión historiográfica para reconstruir el ambiente académico, cultural y humano del Departamento de Filología Semítica en un momento clave de lenta reapertura intelectual. Atraído por la figura de Josep Maria Millàs Vallicrosa, Glick llegó a Barcelona para formarse en árabe y hebreo y para profundizar en la historia medieval de la ciencia, dentro del marco del “humanismo ampliado” de George Sarton, del que Millàs fue uno de los principales valedores en España. El relato destaca la centralidad de Millàs como maestro y articulador de una tradición académica que integraba filología, historia de la ciencia y estudio comparado de las culturas árabe y hebrea, así como el papel de figuras como Joan Vernet, David Romano y otros miembros destacados del entorno semitístico barcelonés. El texto aporta una dimensión humana especialmente rica: la experiencia de Glick como estudiante extranjero, su aprendizaje del catalán en un contexto de restricciones políticas, sus recorridos por la Barcelona histórica y su inserción en redes académicas internacionales. Todo ello se articula mediante la metáfora de la riḥla fī ṭalab al-ʿilm, el viaje en busca del conocimiento, que sirve para situar esta etapa como el inicio de una trayectoria intelectual de largo alcance. La presentación, a cargo de Miquel Forcada, contextualiza el artículo dentro de la historiografía de la ciencia y subraya su valor como homenaje a la Universidad de Barcelona del tardofranquismo y a una generación de estudiosos que mantuvieron viva la investigación en condiciones adversas. El texto se revela así no solo como una memoria personal, sino como una contribución fundamental para comprender la continuidad y la renovación de los estudios semíticos y de la historia de la ciencia en el ámbito hispánico

    Por Luis Albarez como marido, y conjunta persona de Doña Juana Afan de Rivera y Chinchilla, Vezinos de la Ciudad de Murcia, pobres. En el pleyto sobre el indubitado derecho de succession del vinculo, ò fideicomisso, que vacò por fin, y muerte de Don Joseph Afan de Rivera y Chinchilla su hermano ... a la que se han opuesto Doña Nicolasa Afan de Rivera, viuda de Don Alonso Zeldràn, Vecina de dicha Ciudad, y los hijos menores de Don Joseph Afan de Rivera, Vecinos de la Villa de Caravaca

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    Respétase a puntuación orixinalPrecede a tít. texto en latín: "Initium sapientiae est timor domini. Domine libera animam meam alabiis iniquis, et à lingua dolosa. Qui detur tibi, aut quid apponatur tibi ad linguam dolosam. Psalm. 119. Beatus qui intelligit super egenum, et pauperem"Texto asinado polo: "Lic. D. Pedro Joseph Forcada, Durruti y Thomàs"Texto datado en Murciae, 1741[]\p2\s, B-F\p2\s, G\p3\sPort. con orla tip. e grav. xi

    La imaginación como herramienta de conocimiento en Ibn ‘Arabi: Un estudio sobre el acto de creación y adoración como acto de imaginación y representación consciente simultáneo a la trascendencia de dicha representación.

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    Treballs Finals de Grau d'Estudis Àrabs i Hebreus. Facultat de Filologia. Universitat de Barcelona, Curs: 2015-2016, Tutor: Miquel Forcada Nogues[spa] Ibn ‘Arabī, místico andalusí de mediados del siglo XII, es conocido por la universalidad de su doctrina en tanto que trasciende, en lo que se refiere a la explicación y el entendimiento, las ideas de Dios, hombre y mundo, haciéndolas accesibles a cualquier filósofo o religioso letrado de cualquier otra disciplina o religión. La actitud de su doctrina reside en el perfeccionamiento de uno mismo a través de la búsqueda de conocimiento, ya sea por medio de la reflexión o de la imaginación. Concretamente, el papel que la imaginación juega en su visión del mundo es el de la confluencia de opuestos, evitando cualquier extremismo y permitiendo todo lo existente manifestarse en diferentes realidades, sin que una perspectiva elimine a la otra. Esto supone una atrevida asunción de responsabilidad por parte del autor, pues la realidad de las cosas depende del punto de vista desde el cual sean observadas. Esta posición respecto al conocimiento es inteligente al ofrecer un elevado grado de diversidad, pues si no se desestima nada del todo, todo puede utilizarse como herramienta hacia el conocimiento.[eng] Ibn ‘Arabī, mystical andalusí from the second half of the 12th century, is known for its universal doctrine which trascends, in relation to explanation and understanding, the ideas of God, man and world, making them accessible to any philosopher or religious scholar of any other discipline or religious order. The attitude of his doctrine lies in self-oriented perfectionism through the pursuit of knowledge, either through reflection or imagination. Specifically, the role that imagination plays in his view of the world is the confluence of opposites, avoiding any extremism and allowing all the existing manifest in different realities, without one perspective denying the other. This implies a bold assumption of responsability by the hand of the author, as the reality of things depends on the point of view form which they are observed. This position regarding to knowledge is smart as it offers a high grade of diversity, as if you do not reject completely anything, everything may be used as a tool to knowledge

    Teaching Machine Translation to Trainee Translators: a Survey of Their Knowledge and Opinions

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    This paper reports upon a survey carried out among thirty-eight trainee translators who took courses on machine translation. The survey was conducted asking the sample of students to fill out a questionnaire both at the beginning and at the end of the MT course. The questions aimed at assessing the degree of knowledge about MT of the respondents and the opinions and impressions that they accordingly had on it. The results of the questionnaire were elaborated so as to investigate the relationship between the increase in the knowledge about MT after the conclusion of the course, and the corresponding change in the students ’ attitude towards the discipline, which became much less biased and in general fairly positive, thanks to a very successful and rewarding learning process. The paper suggests that the more the trainee translators became familiar with MT, realising its reasonable potential and current limitations, the less afraid they were of it. These findings encourage the increasing integration and introduction of technology into translation curricula, since the impact of computer technology on language translation directly affects professional human translators. As a result, exposing trainee translators to machine translation seems to raise the profile of their training

    Oestrous Activity and Ovulation Rate in Rasa Aragonesa Ewes Maintained at two Different Body Condition Levels Implanted or Reimplanted in the Seasonal Anoestrus with Exogenous Melatonin

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    The effects of melatonin implants in advancing the breeding season and enhancing both ovulation rate (OR) and litter size in the ewe are well documented (Haresign et al., 1990; López and Inskeep, 1991). Likewise, oestrous activity and OR in the early breeding season can be stimulated by a moderately and constant body condition (BC) in Mediterranean sheep breeds (Forcada et al., 1992). However, little information is available in relation to the effect of nutritional status in ewes receiving exogenous melatonin on reproductive parameters. The present study was carried out to determine the effects of a constant BC throughout the year, and implant or reimplant of exogenous melatonin on onset of oestrous activity and OR in a reduced seasonality sheep breed.The experiment was designed as a 2x2 factorial. Factors were two constant BC levels (≤2.50; L, and ≥2.75; H) and two forms of melatonin treatment (one implant -Melovine™- placed the 8th April; M, and a second implant 49 days later; 2M).</jats:p

    Cáculo de estimadores de los Cuadrados Medios y Denominadores de la F

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    Cálculo estimadores CM y denominadores de la F en los análisis de ANOVA multifactorial

    Meta-Evaluation of a Diagnostic Quality Metric for Machine Translation

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    Diagnostic evaluation of machine translation (MT) is an approach to evaluation that provides finer-grained information compared to state-of-the-art automatic metrics. This paper evaluates DELiC4MT, a diagnostic metric that assesses the performance of MT systems on user-defined linguistic phenomena. We present the results obtained using this diagnostic metric when evaluating three MT systems that translate from English to French, with a comparison against both human judgements and a set of representative automatic evaluation metrics. In addition, as the diagnostic metric relies on word alignments, the paper compares the margin of error in diagnostic evaluation when using automatic word alignments as opposed to gold standard manual alignments. We observed that this diagnostic metric is capable of accurately reflecting translation quality, can be used reliably with automatic word alignments and, in general, correlates well with automatic metrics and, more importantly, with human judgements
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