88,838 research outputs found

    The effect of patients’ preference on outcome in the EVerT cryotherapy versus salicylic acid for the treatment of plantar warts (verruca) trial

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    Background Randomised controlled trials are widely accepted as the gold standard method to evaluate medical interventions, but they are still open to bias. One such bias is the effect of patient’s preference on outcome measures. The aims of this study were to examine whether patients’ treatment preference affected clearance of plantar warts and explore whether there were any associations between patients’ treatment preference and baseline variables in the EverT trial. Methods Two hundred and forty patients were recruited from University podiatry schools, NHS podiatry clinics and primary care. Patients were aged 12 years and over and had at least one plantar wart which was suitable for treatment with salicylic acid and cryotherapy. Patients were asked their treatment preference prior to randomisation. The Kruskal-Wallis test was performed to test the association between preference group and continuous baseline variables. The Fisher’s exact test was performed to test the association between preference group and categorical baseline variables. A logistic regression analysis was undertaken with verruca clearance (yes or no) as the dependent variable and treatment, age, type of verruca, previous treatment, treatment preference as independent variables. Two analyses were undertaken, one using the health professional reported outcome and one using the patient’s self reported outcomes. Data on whether the patient found it necessary to stop the treatment to which they had been allocated and whether they started another treatment were summarised by treatment group. Results Pre-randomisation preferences were: 10% for salicylic acid; 42% for cryotherapy and 48% no treatment preference. There was no evidence of an association between treatment preference group and either patient (p=0.95) or healthcare professional (p=0.46) reported verruca clearance rates. There was no evidence of an association between preference group and any of the baseline variables except gender, with more females expressing a preference for salicylic acid (p=0.004). There was no evidence that the number of times salicylic acid was applied was different between the preference groups at one week (p=0.89) or at three weeks (p=0.24). Similarly, for the number of clinic visits for cryotherapy (p=0.71) Conclusions This secondary analysis showed no evidence to suggest that patients’ baseline preferences affected verruca clearance rates or adherence with the treatment

    TLS, 6 Nov 1963

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    Evert tells Barnard she had found an old letter he had written concerning the 13th Sabbath offering. Evert tells JFB that the 13th Sabbath offering will be coming to the Southern African Division again to see if he is interested in making a donation

    Application of linear and nonlinear adaptive filters for the compensation of disturbances in the laminar boundary layer

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    In order to delay the laminar-turbulent transition in the boundary layer of airfoils the compensation of instability waves by artificially excited disturbances is studied. It turns out that also nonlinear processes occur in the spatial development of disturbances. This can be modeled by different types of nonlinear filter structures

    The CogALex-V Shared Task on the Corpus-Based Identification of Semantic Relations

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    The shared task of the 5th Workshop on Cognitive Aspects of the Lexicon (CogALex-V) aims at providing a common benchmark for testing current corpus-based methods for the identifica- tion of lexical semantic relations ( synonymy , antonymy , hypernymy , part-whole meronymy ) and at gaining a better understanding of their respective strengths and weaknesses. The shared task uses a challenging dataset extracted from EVALution 1.0 (Santus et al., 2015b), which contains word pairs holding the above-mentioned relations as well as semantically unrelated control items ( random ). The task is split into two subtasks: (i) identification of related word pairs vs. unre- lated ones; (ii) classification of the word pairs according to their semantic relation. This paper describes the subtasks, the dataset, the evaluation metrics, the seven participating systems and their results. The best performing system in subtask 1 is GHHH ( F 1 = 0 . 790 ), while the best system in subtask 2 is LexNet ( F 1 = 0 . 445 ). The dataset and the task description are available at https://sites.google.com/site/cogalex2016/home/shared-task

    FIGURE. Entoloma argus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (a, d–f, from LE F-312694, holotype; b–c, from LE F-315915). Scale bars a–c 1 cm, d–f 10 μm. Photos by O. Morozova. in Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position

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    FIGURE. Entoloma argus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (a, d–f, from LE F-312694, holotype; b–c, from LE F-315915). Scale bars a–c 1 cm, d–f 10 μm. Photos by O. Morozova.Published as part of Morozova, Olga, Popov, Eugene, Alexandrova, Alina, Pham, Thi Ha Giang & Noordeloos, Machiel Evert, 2022, Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position, pp. 1-21 in Phytotaxa 549 (1) on page 9, DOI: 10.11646/phytotaxa.549.1.1, http://zenodo.org/record/660526

    FIGURE. Entoloma argus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (a, d–f, from LE F-312694, holotype; b–c, from LE F-315915). Scale bars a–c 1 cm, d–f 10 μm. Photos by O. Morozova. in Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position

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    FIGURE. Entoloma argus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (a, d–f, from LE F-312694, holotype; b–c, from LE F-315915). Scale bars a–c 1 cm, d–f 10 μm. Photos by O. Morozova.Published as part of Morozova, Olga, Popov, Eugene, Alexandrova, Alina, Pham, Thi Ha Giang & Noordeloos, Machiel Evert, 2022, Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position, pp. 1-21 in Phytotaxa 549 (1) on page 9, DOI: 10.11646/phytotaxa.549.1.1, http://zenodo.org/record/660526

    FIGURE. Entoloma icarus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (all from LE F-312696, holotype). Scale bars a–c 1 cm, d–f 10 μm. Photos a by E. Popov, b–f by O. Morozova. in Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position

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    FIGURE. Entoloma icarus: a–c. basidiocarps; d. basidiospores; e. cheilocystidia; f. pileipellis (all from LE F-312696, holotype). Scale bars a–c 1 cm, d–f 10 μm. Photos a by E. Popov, b–f by O. Morozova.Published as part of Morozova, Olga, Popov, Eugene, Alexandrova, Alina, Pham, Thi Ha Giang & Noordeloos, Machiel Evert, 2022, Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position, pp. 1-21 in Phytotaxa 549 (1) on page 13, DOI: 10.11646/phytotaxa.549.1.1, http://zenodo.org/record/660526

    FIGURE. Entoloma argus: a. basidiospores; b, c. basidia; d. cheilocystidia (a, b, d, from LE F-312694, holotype; c, from LE F-315915). Scale bars 10 μm. Drawings by O. Morozova. in Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position

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    FIGURE. Entoloma argus: a. basidiospores; b, c. basidia; d. cheilocystidia (a, b, d, from LE F-312694, holotype; c, from LE F-315915). Scale bars 10 μm. Drawings by O. Morozova.Published as part of Morozova, Olga, Popov, Eugene, Alexandrova, Alina, Pham, Thi Ha Giang & Noordeloos, Machiel Evert, 2022, Four new species of Entoloma (Entolomataceae, Agaricomycetes) subgenera Cyanula and Claudopus from Vietnam and their phylogenetic position, pp. 1-21 in Phytotaxa 549 (1) on page 10, DOI: 10.11646/phytotaxa.549.1.1, http://zenodo.org/record/660526

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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