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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The search for common genetic determinants of pre-clinical Alzheimer's disease-related traits
No full textThesis (M.A.)--Boston University
PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [email protected]. Thank you.Background: As Alzheimer's disease (AD) becomes an increasingly urgent public health problem, much effort has been made by medical researchers and public health professionals to further our understanding of AD etiology and causal factors that contribute toward its onset, progression, and severity.
AD research has recently focused on identifying and examining preclinical traits associated with the onset and progression of AD with the goals of early detection discovery, mechanism elucidation, and ultimately treatment and prevention. By understanding the genetic components that make one susceptible to pre-clinical traits that are correlated with future development of AD, we can increase our understanding of what and how genes are involved in the molecular pathways as well as identify risk factors that contribute to the onset of a presently elusive, costly, and devastating disease.
Specific Aims: This study sought to complete the following; identify MRI and cognitive
endophenotypes that are co-heritable with the future onset of Alzheimer's disease; determine cross-trait co-heritability of endophenotypes heritable with AD; select a co-heritable endophenotype combination that has predictive value for AD development; assess which potential genes may be responsible for the co-heritability of this endophenotype combination and prepare for further candidate gene analysis.
Methods: Data from the Framingham Heart Study was analyzed to determine heritability of MRI and cognitive endophenotypes with AD development, and co-heritability of the traits with each other. A bivariate, Genome-Wide Association Study (GWAS) was then conducted on the selected MRI-cognitive endophenotype combination to determine which single nucleotide polymorphisms (SNPs) are most associated with co-heritability of the selected trait combination. The results of the GWAS directed further study, including gene-based association studies and assessment of protein interaction pathways, that resulted in selection of potential candidate genes.
Results: Twenty-four MRI and cognitive traits were found to be heritable with future AD onset. The most co-heritable MRI and cognitive trait combination among the AD-heritable traits was temporal horn brain volume (THBV) and trail-making test B (TrB) scores. This combination was selected to drive our hypothesis of a significant association between pre-clinical endophenotypes and future AD. The GWAS results indicate that several SNP markers are associated with the co-heritability of THBV and TrB scores. Subsequent regional analyses implicate several genes likely to be causally involved in expression of this endophenotype expression, including SPON1, which directly interacts with APP. Based on a combination of evidence, the genes selected for candidate gene analysis are SPON1, DICER1, GPR177, ADCY9, VAMP3, and FOXF2.
Conclusion: Our study validated several previous findings of MRI and cognitive heritability with AD. We then used estimates of co-heritability to successfully run a bivariate analysis of two pre-clinical traits to identify genes explaining their impact on future AD development. The genes selected for candidate gene analysis appear to be involved in amyloid precursor protein processing, which is the primary pathway that leads to plaque deposition and AD pathology. Further study of these genes, especially SPON1, will allow for determination of replicable findings, assessment of whether the candidate genes are causative, and determination of whether these genes are also related to progression and severity of AD symptoms. Importantly, this method of gene discovery, through bivariate analyses of pre-clinical traits, allows for insights into disease
susceptibility, molecular pathways, early detection, and more focused treatments
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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