67 research outputs found

    Crystal structure of lizardite 1T from Elba Island, Italy

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    Euhedral lizardite-1T occurs in the Monte Fico quarries, Elba Island, Italy. Unit-cell parameters, for two crystals, each with space group P31m, are a = 5.338(4) and c = 7.257(6) and a = 5.330(4) and c = 7.269(6) Å. The crystal structures were refined to Rtot = 0.034 and 0.046, using 251 and 849 independent reflections, respectively. The topology determined from previous refinements is confirmed. -from Author

    Novel PET Imaging Techniques in the Management of Hematologic Malignancies

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    Hematology is probably the most relevant application field of PET since the widespread adoption of PET in the 1990s. Currently, the use of PET is indispensable in the natural history of almost all onco-hematologic diseases. With the advent of innovative therapies, such as CAR-T, the use of PET has gained further clinical diagnostic value. Significant innovations are also seen in the therapeutic and theranostic fields, and greater developments are anticipated in the future. Ultimately, the clinical applications of PET in onco-hematology likely represent the largest portion of the daily workload in most PET centers, and clinical hematologists have long relied on these molecular imaging techniques. In the current issue, we have asked leading international experts in onco-hematology imaging and therapy to contribute their insights on the state-of-the-art applications of PET and therapeutic techniques in major hematologic diseases and to provide perspectives on potential future diagnostic and therapeutic applications in this field. Despite the necessarily limited space, we have endeavored to cover all relevant topics. Contributions have come from top experts in both established application fields, which constitute the daily practice, such as in the article “[18F]FDG PET Imaging for Therapy Assessment in Hodgkin and Non-Hodgkin Lymphomas" by the group led by Prof Roland Hustinx, and in new diagnostic possibilities in the article "New PET Tracers for Lymphoma." Therapeutic applications also have an important focus: the past and future of therapeutic applications in lymphomas have been brightly reported by a leading expert, such as Prof Elba Etchebehere, and collaborators. We have given ample space to current and future diagnostic applications in Multiple Myeloma, including a comparison of PET imaging with whole-body MR imaging. This issue would not be complete without mentioning the contribution of new PET machines with long axial fields of view, with an interesting article by Prof Nardo from the University of California, Davis, or the applications of PET in Chimeric Antigen Receptor T-Cell Trafficking, radiomics, or new quantitative PET methods in onco-hematology. In conclusion, the use of PET and radioligand therapies in onco-hematology constitutes the present of our daily activities, but innovations in new theranostic radiopharmaceuticals and technological advancements ensure an increasingly bright future and an ever-greater significance of molecular imaging in onco-hematology. We want to thank all the authors and collaborators for their spontaneous, free, and enthusiastic contributions to this project, which will undoubtedly be a valuable resource for both clinicians and imaging experts

    Evaluation Of Soft-tissue Lesions With (18)f-fdg Pet/ct: Initial Results Of A Prospective Trial.

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    Although MRI is utilized for planning the resection of soft-tissue tumors, it is not always capable of differentiating benign from malignant lesions. The risk of local recurrence of soft-tissue sarcomas is increased when biopsies are performed before resection and by inadequate resections. PET associated with computed tomography using fluorodeoxyglucose labeled with fluorine-18 ((18)F-FDG PET/CT) may help differentiate between benign and malignant tumors, thus avoiding inadequate resections and making prior biopsies unnecessary. The purpose of this study was to evaluate the usefulness of (18)F-FDG PET/CT in differentiating benign from malignant solid soft-tissue lesions. Patients with solid lesions of the limbs or abdominal wall detected by MRI were submitted to (18)F-FDG PET/CT. The maximum standardized uptake value (SUVmax) cutoff was determined to differentiate malignant from benign tumors. Regardless of the (18)F-FDG PET/CT results all patients underwent biopsy and surgery. MRI was performed in 54 patients, and 10 patients were excluded because of purely lipomatose or cystic lesions. (18)F-FDG PET/CT was performed in the remaining 44 patients. Histopathology revealed 26 (59%) benign and 18 (41%) malignant soft-tissue lesions. A significant difference in SUVmax was observed between benign and malignant soft-tissue lesions. The SUVmax cutoff of 3.0 differentiated malignant from benign lesions with 100% sensitivity, 83.3% specificity, 89.6% accuracy, 78.3% positive predictive value, and 100% negative predictive value. (18)F-FDG PET/CT seems to be able to differentiate benign from malignant soft-tissue lesions with good accuracy and very high negative predictive value. Incorporating (18)F-FDG PET/CT into the diagnostic algorithm of these patients may prevent inadequate resections and unnecessary biopsies.35252-

    Parasigara perdubia WME X X

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    Parasigara perdubia (Rey, 1894) Parasigara perdubia Jansson 1986: 53 (displayed on map); Bacchi and Rizzotti Vlach 2005: CD-ROM; 2007: CD-ROM; Cianferoni 2011: 260; Cianferoni and Terzani in print. Records. Capraia. Capraia Island, 1–2.V.1982, S. Taiti & S. Vanni leg., 3 ££ macr, MZUF (!) [TOSCANA Isola di Capraia (LI) / 1–2/V/1982 S. Taiti & S. Vanni! // Parasigara / perdubia (Rey) / det. A. Jansson] (Jansson 1986: material examined by the author as deducible by map and data sources; Cianferoni & Terzani in print as “ Jansson (1986: 53) […] Isola di Capraia”); Vado del Porto, 1993, CMR (Bacchi & Rizzotti Vlach, 2005, 2007 as “Isola di Capraia, Vado del Porto / Coll. Rizzotti Vlach / 1993”; Cianferoni 2011 as “Capraia Island […] (Bacchi & Rizzotti Vlach 2005)”; Cianferoni & Terzani in print as “Capraia […] Bacchi & Rizzotti Vlach (2005) ”). Elba. Fosso della Gneccarina, surroundings of Chiessi, 20–50 m, Marciana (LI), 23.VII.1982, F. Terzani leg., 1 £, CFT [Sigara sp. ♀ / Det. Tamanini L. / 1986]; Fosso dell’Inferno, Seccheto, Campo nell’Elba (LI), 14.IX.2012, C. Monte & L. Forbicioni leg., 1 $, 5 ££ macr, CFC; idem, L. Forbicioni & C. Monte leg., 4 ££ macr, CLF (Cianferoni & Terzani in print as “Elba”). Remarks. First precise records for the Isle of Elba. The presence of P. perdubia on this island was reported without precise locality in Cianferoni (2011) and Cianferoni and Terzani (in print). It is a W-Mediterranean element.Published as part of Cianferoni, Fabio, Rocchi, Saverio & Terzani, Fabio, 2013, Nepomorpha, Gerromorpha and Leptopodomorpha (Hemiptera: Heteroptera) of the Tuscan Archipelago (Italy), pp. 302-320 in Zootaxa 3669 (3) on page 305, DOI: 10.11646/zootaxa.3669.3.6, http://zenodo.org/record/526667

    Corixa punctata CEM X X

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    Corixa punctata (Illiger, 1807) Corixa Geoffroyi Mancini 1935: 14. Corixa punctata Servadei 1967: 4; Jansson 1986: 41 (displayed on map); Bacchi and Rizzotti Vlach 2005: CD-ROM; 2007: CD-ROM. Records. Capraia. Lo Stagnone, [1927–1931], C. Mancini leg., CMG (Mancini 1935 as “[Isola di Capraia] Comunissima allo Stagnone”; Servadei 1967 as “I. Capraia: Mancini 1935 ”); Vado del Porto, [1927–1931], C. Mancini leg., CMG (Mancini 1935 as “[Isola di Capraia] Comunissima […] al Vado del Porto”; Servadei 1967 as “I. Capraia: Mancini 1935 ”); Capraia Island, 1927, MSNM (Bacchi & Rizzotti Vlach 2005; 2007 as “Isola di Capraia / Coll. Mus. Civ. St. Nat. Milano / 1927”); Vado del Porto, 1927, MSNM (Bacchi & Rizzotti Vlach 2005; 2007 as “Isola di Capraia, Vado del Prato [misspelling for “Porto”] / Coll. Mus. Civ. St. Nat. Milano / 1927”); Vado del Porto, 1927, MSNM (Bacchi & Rizzotti Vlach 2005; 2007 as “Isola di Capraia, Vado del Porto / Coll. Mus. Civ. St. Nat. Milano / 1927”); Lo Stagnone, 1927, MSNM (Bacchi & Rizzotti Vlach 2005; 2007 as “Isola di Capraia, Lo Stagnone / Coll. Mus. Civ. St. Nat. Milano / 1927”); Lo Stagnone, 1930, MSNM (Bacchi & Rizzotti Vlach 2005; 2007 as “Isola di Capraia, Lo Stagnone / Coll. Mus. Civ. St. Nat. Milano / 1930”); Capraia Island (Jansson 1986: material examined by the author, deducible by map). Elba. Isle of Elba (Jansson 1986: material examined by the author, deducible by map); Monte Calamita, Ripalte, Capoliveri (LI), 30.X.2011, L. Forbicioni & G. Frangini leg., 1 $, 2 ££ macr, CLF; Fosso di Remaiolo, dam, 170 m, Capoliveri (LI), 14.VII.2012, C. Monte & L. Forbicioni leg., 1 £, CFC Remarks. First precise records for the Isle of Elba. Its presence on this island had previous only been recorded on a map in Jansson (1986: 41). Common species, sometimes also collected in brackish waters (Scudder 1976, Tamanini 1979).Published as part of Cianferoni, Fabio, Rocchi, Saverio & Terzani, Fabio, 2013, Nepomorpha, Gerromorpha and Leptopodomorpha (Hemiptera: Heteroptera) of the Tuscan Archipelago (Italy), pp. 302-320 in Zootaxa 3669 (3) on page 305, DOI: 10.11646/zootaxa.3669.3.6, http://zenodo.org/record/526667

    Open resection of osteoid osteoma guided by a gamma-probe

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    Osteoid osteoma is the third most common type of bone tumour. Radiofrequency ablation and other percutaneous procedures are the treatment of choice. However, in some sites these methods are difficult or dangerous. Our objective of this study was to evaluate whether open resection and intraoperative nidus detection with a hand-held gamma probe is an efficient method for treating this type of tumour. Fifty-three patients with osteoid osteomas were submitted to surgical treatment. The first group (gamma group) consisted of 34 patients submitted to open nidus resection guided by a hand-held gamma probe. The control group consisted of 19 patients operated on by conventional technique. In the postoperative period, histopathology, imaging studies, and clinical outcome were evaluated. The gamma group patients were followed up for an average 26.2 months; the control group patients were followed up for an average 38 months. There was no difference with regard to pain relief and histopathology findings between the two groups. However, in the postoperative imaging studies, there was significantly less nidus present in the gamma group (p=0.01). The gamma probe helped to locate the osteoid osteoma nidus more precisely, as demonstrated by the postoperative imaging studies.33121922
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