1,720,986 research outputs found

    Investigation of toxoplasmosis seropositivity in pregnants between january 2014 and january 2019 and clinical follow-up and results in patients with igm positivity

    No full text
    Ocak 2014-Ocak 2019 Arasında Gebelerde Toksoplazmozis Seropozitivitesinin Araştırılması ve IgM Pozitifliği Tespit Edilenlerde Klinik Takip ve Sonuçları Bu çalışmada Afyonkarahisar Sağlık Bilimleri Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalı ve Enfeksiyon Hastalıkları Anabilim Dalı'na başvuran gebelerin Toksoplazma gondii etkeni ile karşılaşma durumlarının araştırılması ayrıca klinik ve laboratuvar bulguları ile Toksoplazmozis ön tanısı alan gebelerde enfeksiyonun takibi ve bebeklerinde konjenital toksoplazma enfeksiyonu varlığının değerlendirilmesi amaçlandı. Ocak 2014-Ocak 2019 tarihleri arasında normal gebelik takibi amacıyla 15-49 yaş arasındaki 4231 gebenin T. gondii enfeksiyonuna ilişkin klinik ve laboratuvar bulguları ile akut toksoplazma şüphesi ile tedavi alanların fetüs ve yenidoğanlarının enfeksiyona ilişkin durumlarını gösterir kayıtlar değerlendirildi. ELISA yöntemi kullanılarak toksoplazma IgG ve toksoplazma IgM seropozitiflikleri ve IgG avidite sonuçları tespit edildi. Çalışmaya dahil edilen bütün gebeler incelendiğinde toksoplazma IgG ve toksoplazma IgM için seropozitiflik oranları sırasıyla %25.5 ve %2.3 olarak saptandı. Yaş arttıkça toksoplazma IgG ve IgM prevalansının arttığı saptandı. Otuz dokuz gebede avidite test sonucu düşük, 9 gebede avidite sonucu orta ve 50 gebede yüksek avidite olarak saptandı. Düşük ve orta avidite değerlerine sahip tüm gebeler ile yüksek aviditeye sahip elli gebeden reaktivasyon düşünülen on beşi olmak üzere toplam 63 gebe tedavi grubunu oluştururken yüksek avidite değerleri saptanan 35 gebeye tedavi başlanmayarak gebelik sonuna kadar izlendi. Tedavi alan gebelerin 45 (%71.4)'i tedaviye uyum gösterirken 18 (%28.6)'i tedaviye uyum sağlamadı. Tedavi uyumlu gebelerin fetüs veya yenidoğanlarının alttı (%13)'sı IUGG ve/veya abortus ile neticelendi. Buna karşın tedavi uyumsuz gebelerin fetüs veya yenidoğanlarının 8 (%44.4)'i IUGG ve/veya abortus ile sonuçlandı. Gebelerin yapılan ultrasonografik incelemesinde 13'ünde IUGG, ikisinde plasental değişiklikler, birinde bağırsak anomalisi, dördünde kardiyak ritim bozukluğu, birinde perikardiyal efüzyon, ikisinde kardiyak anomali, dördünde hidrosefali, ikisinde spina bifida, ikisinde meningomyelosel, ikisinde ventrikülomegali saptandı. Sonuç olarak düşük veya ölü doğumlara sebep olabilen Toksoplazma gondii etkeninin bölgemizdeki gebe hastalarda halen önemini koruyan sağlık sorunları arasındadır. Serolojik yöntemlerin bu enfeksiyonların teşhisinde ve IgG avidite testi yapılarak şüpheli durumların netleştirilmesinde hekime yol gösterici bir yöntem olabileceğini düşünmekteyiz. Bununla beraber toksoplazma enfeksiyonu sonucunda IgM pozitifliğinin ve düşük avidite değerlerinin uzun süre devam edebilmesi gebelik döneminde akut toksoplazmozun ekarte edilebilmesini güçleştirdiği için serolojik olarak IgM ve IgG ile beraber aviditenin değerlendirilmesi doğru tanı açısından önemlidir. Anahtar Kelimeler: Toksoplazmozis, Seroprevalans, Toksoplazma gondii, Avidite, SpiramisinInvestigation of Toxoplasmosis Seropositivity in Pregnant Women Between January 2014-January 2019 and Clinical Follow-up and Results in Patients with IgM Positivity The aim of this study was to investigate the presence of Toxoplasma gondii in pregnant women who applied to Afyonkarahisar University of Health Sciences, Department of Obstetrics and Gynecology and Infectious Diseases. In addition, clinical and laboratory findings and the diagnosis of toxoplasmosis in pregnant women with the diagnosis of congenital toxoplasmosis infection was aimed to be followed. The clinical and laboratory findings of 4231 pregnant women between 15-49 years of age between January 2014 and January 2019 for the follow-up of normal pregnancies and records showing the infection status of fetuses and neonates of patients treated with suspected acute toxoplasma were evaluated. Toxoplasma IgG and toxoplasma IgM seropositivity and IgG avidity were determined using ELISA method. Seropositivity rates of toxoplasma IgG and toxoplasma IgM were 25.5% and 2.3%, respectively. The prevalence of toxoplasma IgG and IgM increased with increasing age. Avidity test results were low in 39 pregnant women, moderate avidity in 9 pregnant women and high avidity in 50 pregnant women. Sixty-three of the pregnant women with low and moderate avidity and fifty pregnant women with high avidity were included in the treatment group. Forty-five (71.4%) of the pregnant women who were treated showed compliance with treatment, while 18 (28.6%) did not. Six (13%) of fetuses or newborns of treatment-compatible pregnant women resulted in IUGR and / or abortion. In contrast, 8 (44.4%) of fetuses or newborns of non-compliant pregnancies resulted in IUGR and / or abortion. Ultrasonographic examination of pregnant women revealed IUGR in 13, placental changes in two, intestinal anomaly in one, cardiac dysrhythmia in four, pericardial effusion in one, cardiac failure in two, hydrocephalus in two, spina bifida in two, meningomyelocele in two, and ventriculomegaly in two. As a result, Toxoplasma gondii, which can cause miscarriages or stillbirths, is still among the important health problems in pregnant women in our region. We argue that serological methods can be used as a guide for physicians in the diagnosis of these infections and in clarifying suspicious situations by using IgG avidity test. However, the fact that IgM positivity and low avidity values persist for a long time as a result of toxoplasma infection makes it difficult to rule out acute toxoplasmosis during pregnancy, it is important to evaluate serological IgM and IgG together with avidity in the right diagnosis. Key Words: Toxoplasmosis, Seroprevalence, Toxoplasma gondii, Avidity, Spiramyci

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Get PDF
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

    Get PDF
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Get PDF
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

    Get PDF
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

    No full text
    Nao informado

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

    No full text
    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Author Under Sail The Imagination of Jack London, 1893-1902

    No full text
    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
    corecore