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    The use of health economic evaluations in pharmaceutical priority setting - The case of Sweden

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    The production of health economic evaluations of pharmaceuticals is a global, multibillion dollar industry. Despite this fact, little is known about what happens after a health economic evaluation has been produced. Will it be used at all, and if so, how? Who uses economic evaluations and for what purposes? Are there differences in the use patterns between decision makers at macro, meso and micro levels? Are decision makers willing and able to use them, and to what extent can the patterns be explained by contextual factors? This dissertation aims to provide answers to these questions. The concepts "use" and "barriers to use" are developed and the influence of contextual factors, demands for transparency, internal and external institutions, and logics on the use patterns are investigated. The use and barriers to use are addressed by an empirical investigation of Swedish pharmaceutical decision makers at the Dental and Pharmaceutical Benefits Agency (TLV), a county council formulary committee and prescribing physicians. Differences in the use patterns and the barriers to use are found among the Swedish macro (TLV), meso (county council formulary committee) and micro (physicians) decision makers. The findings from the empirical research on Swedish decision makers are also contrasted with decision makers in other countries in a systematic literature review. Through triangulation of observations, interviews and analysis of documents it is suggested that the use may be defined according to the purpose of the use and consequently the phase of the priority setting process (i.e. preparation, expert comments, decision making or launch). In addition, a conceptual model of the use and barriers related to the acceptability of health economic evaluations among decision makers is suggested, integrating findings from research in health economics, priority setting and institutional theory. According to this model, barriers to use may be explained by six factors ; 1) budget restrictions, 2) decision making rules used to reduce uncertainty, 3) demand for transparency, 4) internal institutions, 5) external institutions, and 6) the existence of prevailing templates

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    The use (or rather the non-use) of cost-effectiveness data in priority setting decisions – are we underestimating the barriers to using health economics in real world priority setting decisions? Comment on “Use of cost-effectiveness data in priority setting decisions: experiences from the national guidelines for heart diseases in Sweden”

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    After having practicing and researching health economics for nearly 15 years now, it has become clear to me that the use of cost-effectiveness data in priority setting decisions is rather a rare than a common practice. The Eckard et al. article though, describes a wonderful exception to this rule and a very good example of how it can be used when the conditions are right. However, do we fully understand what these conditions are? In this commentary article I will address some of the institutional and cultural conditions that need to be fulfilled in order for cost-effectiveness data to actually be used in priority setting decision
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