1,721,097 research outputs found

    Scopolamine effects on ultrasonic vocalization emission and behavior in the neonatal mouse

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    Developmental alterations of the cholinergic system can lead to short- and long-term detrimental consequences for brain function. In order to study the cholinergic modulation of behavior in the neonatal mouse, we characterized ultrasonic vocalizations and spontaneous behavior of 5- and 8-day old CD-1 Swiss mice after i.p. administration of the muscarinic antagonist scopolamine (doses, 0.8 and 2mg/kg) during both a first isolation of 30 min and a re-isolation of 5min, occurring immediately after a brief reunion with the mother. As concerns the first isolation, on PND 5, only scopolamine 0.8 mg/kg increased the number of ultrasonic vocalizations and, on PND 8, both doses increased it in a dose-dependent fashion. Scopolamine effects on spontaneous behavior were very limited on PND 5, but markedly evident on PND 8, the high dose increasing activity profile. Independently from treatment, the brief reunion with the mother had no effects on mouse ultrasound emission during re-isolation. The present results show that the cholinergic system plays a role in inhibiting rodent pup USV emission and spontaneous behavior and suggest that the analysis of spontaneous behavior and, in particular, of the number of ultrasonic vocalizations represents a valuable tool to detect precocious developmental alterations of the cholinergic function in the mouse, the most used animal species to model human health disorders

    Agricoltura sociale: la produzione innovativa di salute

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    L'articolo presenta una riflessione sul concetto di inclusione sociale attiva nelle pratiche di agricoltura sociale. Il concetto è poi stato ripreso su scala comunitaria dalle politiche social

    sj-pdf-1-lan-10.1177_00236772221111261 - Supplemental material for General and species-specific recommendations for minimal requirements for the use of cephalopods in scientific research

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    Supplemental material, sj-pdf-1-lan-10.1177_00236772221111261 for General and species-specific recommendations for minimal requirements for the use of cephalopods in scientific research by Giovanna Ponte, Katina Roumbedakis, COST Action FA1301, Viola Galligioni, Ludovic Dickel, Cécile Bellanger, Joao Pereira, Erica AG Vidal, Panos Grigoriou, Enrico Alleva, Daniela Santucci, Claudia Gili, Giovanni Botta, Pamela Imperadore, Andrea Tarallo, Lars Juergens, Emily Northrup, David Anderson, Arianna Aricò, Marianna De Luca, Eleonora Maria Pieroni, Graziano Fiorito in Laboratory Animals</p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Variation in Environmental Parameters in Research and Aquaculture: effects on behaviour, physiology and cell Biology of Teleost fish

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    Over the last few years the increasing use of fish as animal models in scientific research and the increased fish breeding for human consumption have stressed the need for more knowledge on the effect of variations in environmental parameters on fish biology and on the welfare of specimens used both in research and aquaculture contexts. Experimental evidence shows that environmental variations can affect fish biology at various levels, from the molecular to that of the population, sometimes in a different way depending on the species considered. In order to achieve reproducible results in experiments involving fish it is necessary to set and maintain all environmental parameters constant at the optimal value to guarantee the wellness of the animal. The effects of the variation in environmental parameters on the behaviour, physiology and cell biology of teleosts are here discussed in order to provide useful information for research based on fish models

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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