309 research outputs found
An integrative evidence review on service user participation in the design and delivery of drug treatment, recovery and harm reduction services.
No full textThis study aims to provide an overview of what user involvement entails within the context of drug treatment services in Ireland. The objective of the study is to provide policy-makers, practitioners, researchers and service users with a clearer understanding of the challenges associated with user involvement, a fundamental paradigm or principle when seeking to develop more effective and satisfactory services. The study involved a lengthy and complex series of research tasks, including an extensive literature search, a service user consultation and discussions with a number of stakeholders. Julie Glanville was responsible for designing the literature search, Feline Engling Cardoso coordinated the stakeholder interviews and Jonathan Pratschke carried out the service user consultation, as well as analysing the interview transcripts and supervising the study. Brian Galvin from the Health Research Board provided oversight and guidance, the Royal College of Physicians of Ireland provided ethical approval for the service user consultation
8th Annual Feline Practitioners Seminar
No full textContents of this seminar include: Perspectives on vaccines in feline practice (Cynthia L. Bowlin); Hitting the bull's eye: Targeting connections between vaccines and cancer in cats (Philip H. Kass); Theory and practice of immunization (Ronald D. Schultz); Duration of immunity for feline biologics (Fred W. Scott); Feline infectious diseases (Fred W. Scott); Overview of feline biologics (Fred W. Scott); Licensing of feline biologics (Ted Williams); Vaccine site associated sarcomas: The Vancouver experience ([no author given])
Sterben im Krankenhaus und hospizfreundliche Krankenhäuser. Reflexionen aus Irland
No full textThe chapter assesses the quality of care provided by Irish hospitals in the last week of life. It is based on the results of a project funded by the Hospice-friendly Hospitals Programme (2007-2012) and contributes to the growing practice within the Irish hospital system of auditing performance against standards in order to ensure that every aspect of its work meets, and even exceeds, the highest standards of care and excellence. The chapter addresses a number of questions, the first of which is "how good are the care outcomes for patients who die in Irish hospitals compared to hospitals elsewhere?" The second is "which care inputs have a significant and substantial influence on care outcomes?" The third is: "how can the findings be used to improve the quality of end-of-life care in Irish hospitals?" In order to answer these questions, data were collected from nurses, doctors and relatives who spent the most time with a sample of 1,000 patients during their last week of life. Each hospital completed the audit on a random sample of 50 deaths in the four month period between November 2008 and February 2009. As a proportion of total deaths in Ireland in 2008, this is a representative sample of 10% of acute hospital deaths and 29% of community hospital deaths.
The research was carried out in 24 acute hospitals which constitute three quarters of the acute hospital sector in Ireland. Data collection was also completed in 19 community hospitals which represents 20% of community hospital beds in the country
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes
No full textBackground Over the past years a variety of host restriction genes have been identified in human and mammals that modulate retrovirus infectivity, replication, assembly, and/or cross-species transmission. Among these host-encoded restriction factors, the APOBEC3 (A3; apolipoprotein B mRNA-editing catalytic polypeptide 3) proteins are potent inhibitors of retroviruses and retrotransposons. While primates encode seven of these genes (A3A to A3H), rodents carry only a single A3 gene. Results Here we identified and characterized several A3 genes in the genome of domestic cat (Felis catus) by analyzing the genomic A3 locus. The cat genome presents one A3H gene and three very similar A3C genes (a-c), probably generated after two consecutive gene duplications. In addition to these four one-domain A3 proteins, a fifth A3, designated A3CH, is expressed by read-through alternative splicing. Specific feline A3 proteins selectively inactivated only defined genera of feline retroviruses: Bet-deficient feline foamy virus was mainly inactivated by feA3Ca, feA3Cb, and feA3Cc, while feA3H and feA3CH were only weakly active. The infectivity of Vif-deficient feline immunodeficiency virus and feline leukemia virus was reduced only by feA3H and feA3CH, but not by any of the feA3Cs. Within Felidae, A3C sequences show significant adaptive selection, but unexpectedly, the A3H sequences present more sites that are under purifying selection. Conclusion Our data support a complex evolutionary history of expansion, divergence, selection and individual extinction of antiviral A3 genes that parallels the early evolution of Placentalia, becoming more intricate in taxa in which the arms race between host and retroviruses is harsher
Dying in Hospital in Ireland: An Assessment of the Quality of Care in the Last Week of Life, National Audit Report 5: Final Synthesis Report
No full textThis publication draws together the key findings from the first-ever National Audit of End-of-Life Care in Hospital in Ireland, 2008/9, commissioned by the Irish Hospice Foundation. The audit system of the Hospice friendly Hospitals Programme (HfF) is the first major initiative in an EU country to develop a comprehensive assessment of standards for end-of-life care in the hospital setting. The study involved the detailed capture of information on the end-of-life care experience of over 1,000 patients in 43 participating acute and community hospitals throughout Ireland. The first phase of the study commenced in November 2008 and finished at the end of 2009. The Evaluation was co-ordinated by Dr. Kieran McKeown. Trutz Haase and Jonathan Pratschke were responsible for all data analysis
Determinants of care outcomes for patients who die in hospital in Ireland: A retrospective study
No full textMore people die in hospital than in any other setting which is why it is important to study the outcomes of hospital care at end of life. This study analyses what influenced outcomes in a sample of patients who died in hospital in Ireland in 2008/9. The study was undertaken as part of the Irish Hospice Foundation’s Hospice Friendly Hospitals Programme (2007–2012). Methods: Outcomes of care were assessed by nurses, doctors and relatives who cared for the patient during the last week of life. Multi-level modelling was used to analyse how care outcomes were influenced by care inputs. Results: The sample of 999 patients represents 10% of acute hospital deaths and 29% of community hospital deaths in Ireland in 2008/9. Five care outcomes were assessed for each patient: symptom experience, symptom management, patient care, acceptability of the way patient died, family support. Care outcomes during the last week of life tended to be better when: the patient had cancer; admission to hospital was planned rather than emergency; death occurred in a single room or where privacy, dignity and environment of the ward was better; team meetings were held; there was good communication with patients and relatives; relatives were facilitated to stay overnight and were present at the time of death; nursing staff were experienced and had training in end-of-life care; the hospital had specific objectives for developing end-of-life care in its service plan. Conclusions: The study shows significant differences in how care outcomes, including pain, were assessed by nurses, doctors and relatives. Care inputs operate in a mutually reinforcing manner to generate care outcomes which implies that improvements in one area are likely to have spillover effects in others. Building on these findings, the Irish Hospice Foundation has developed an audit and review system to support quality improvement in all care settings where people die
Canine and feline infectious diseases /
No full textCanine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination.Includes bibliographical references and index.Basic principles in the diagnosis and management of small animal infection -- Laboratory diagnosis of canine and feline infectious diseases -- Isolation in cell culture -- Immunoassays -- Isolation and identification of aerobic and anaerobic bacteria -- Isolation and identification of fungi -- Nucleic acid detection assays -- Antiinfective therapy -- Principles of antiinfective therapy -- Antiviral and immunomodulatory drugs -- Antibacterial drugs -- Antifungal drugs -- Antiprotozoal drugs -- Basic principles for infection control -- Infection control programs for dogs and cats -- Immunization -- Major infectious diseases and their etiologic agents -- Viral diseases -- Rabies -- Canine parvovirus infections and other viral enteritides -- Canine distemper virus infection -- Canine herpesvirus infection -- Canine viral respiratory infections -- Infectious canine hepatitis -- Feline panleukopenia virus infection and other viral enteritides -- Feline coronavirus infection -- Feline immunodeficiency virus infection -- Feline leukemia virus infection -- Feline respiratory viral infections -- Feline poxvirus infections -- Pseudorabies -- Viral papillomatosis -- Vector-borne and other viral encephalitides -- Bacterial diseases -- Ehrlichiosis -- Anaplasmosis -- Rocky mountain spotted fever -- Salmon poisoning disease -- Coxiellosis and q fever -- Chlamydial infections -- Streptococcal and enterococcal infections -- Staphylococcus infections -- Gram-negative bacterial infections -- Anaerobic bacterial infections -- Bordetellosis -- Cell wall-deficient bacterial infections -- Mycoplasma infections -- Hemoplasma infections -- Actinomycosis -- Nocardiosis -- Mycobacterial infections -- Salmonellosis -- Enteric Escherichia coli infections -- Campylobacteriosis -- Enteric clostridial infections -- Gastric Helicobacter-like infections -- Leptospirosis -- Lyme borreliosis -- Bartonellosis -- Canine brucellosis -- Tetanus and botulism -- Yersinia pestis (plague) and other yersinioses -- Tularemia -- Bite and scratch wound infections -- Fungal and algal diseases -- Dermatophytosis -- Malassezia infections -- Blastomycosis -- Histoplasmosis -- Cryptococcosis -- Coccidioidomycosis -- Sporotrichosis -- Aspergillosis -- Rhinosporidiosis -- Candidiasis -- Miscellaneous fungal diseases -- Pythiosis, lagenidiosis, and zygomycosis -- Protothecosis -- Pneumocystosis -- Protozoal diseases -- Toxoplasmosis -- Neosporosis -- Leishmaniosis -- Babesiosis -- Cytauxzoonosis -- Canine and feline hepatozoonosis -- Trypanosomiasis -- Giardiasis -- Trichomoniasis -- Cryptosporidiosis -- Isosporiasis -- Miscellaneous protozoal diseases -- Infections of selected organ systems -- Pyoderma, otitis externa, and otitis media -- Osteomyelitis, discospondylitis, and infectious arthritis -- Infections of the cardiovascular system -- Bacterial bronchopneumonia and pyothorax -- Intra-abdominal infections -- Bacterial infections of the genitourinary tract -- Bacterial meningitis -- Vaccination schedules for dogs and cats.Online resource; title from resource home page (ScienceDirect, viewed on October 25, 2013).Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination.Elsevie
Canine and feline respiratory medicine /
No full text"This comprehensive reference provides readers with everything they need to know about diagnosing and treating canine and feline respiratory disease. Significantly updated and expanded, it focuses on localization of disease, efficient diagnostic testing, and appropriate therapy. With more images, discussion, and diagrams, this Second Edition includes more detail and new information throughout, particularly in the areas of antimicrobial guidelines, anti-fungal therapies, and ant-viral medications in cats. Logically organized for ease of use in the practice setting, Canine and Feline Respiratory Medicine, Second Edition features problem-based learning to enhance working knowledge of the topics discussed. Chapters cover localization of disease, respiratory diagnostics, respiratory therapeutics, nasal disorders, and diseases of airways. Sections on parenchymal disease; pleural and mediastinal disease; and vascular disorders are also presented. Canine and Feline Respiratory Medicine is an essential resource for veterinary internal medicine specialists, general practitioners, and veterinary students. Offers a complete guide to the diagnosis and treatment of respiratory conditions in canine and feline patients--now expanded to include more detailed and advanced information. Focuses on localization of disease, diagnostic testing, and appropriate therapy. Thoroughly updated with new antimicrobial guidelines, the latest information on anti-fungal therapy, and new advances in ant-viral medications in cats. Includes many new images and topics for discussion. Features problem-based learning exercises to support a working understanding of the topics discussed"--Preceded by Clinical canine and feline respiratory medicine / Lynelle R. Johnson. 2010.Includes bibliographical references and index.Localization of Disease -- Respiratory Diagnostics -- Respiratory Therapeutics -- Nasal Disorders -- Diseases of Airways -- Parenchymal Disease -- Pleural and Mediastinal Disease -- Vascular Disorders."This comprehensive reference provides readers with everything they need to know about diagnosing and treating canine and feline respiratory disease. Significantly updated and expanded, it focuses on localization of disease, efficient diagnostic testing, and appropriate therapy. With more images, discussion, and diagrams, this Second Edition includes more detail and new information throughout, particularly in the areas of antimicrobial guidelines, anti-fungal therapies, and ant-viral medications in cats. Logically organized for ease of use in the practice setting, Canine and Feline Respiratory Medicine, Second Edition features problem-based learning to enhance working knowledge of the topics discussed. Chapters cover localization of disease, respiratory diagnostics, respiratory therapeutics, nasal disorders, and diseases of airways. Sections on parenchymal disease; pleural and mediastinal disease; and vascular disorders are also presented. Canine and Feline Respiratory Medicine is an essential resource for veterinary internal medicine specialists, general practitioners, and veterinary students. Offers a complete guide to the diagnosis and treatment of respiratory conditions in canine and feline patients--now expanded to include more detailed and advanced information. Focuses on localization of disease, diagnostic testing, and appropriate therapy. Thoroughly updated with new antimicrobial guidelines, the latest information on anti-fungal therapy, and new advances in ant-viral medications in cats. Includes many new images and topics for discussion. Features problem-based learning exercises to support a working understanding of the topics discussed"--Description based on online resource; title from digital title page (viewed on January 30, 2020).John Wiley and Son
Atlas of canine and feline peripheral blood smears /
No full text"An illustrated guide to the morphology of blood cells, Atlas of Canine and Feline Peripheral Blood Smears covers patient assessment for common hematologic disorders and diseases in dogs and cats. Over 1,000 full-color photomicrographs depict abnormalities within each blood cell line, with multiple pictures of each morphologic abnormality and variations in their appearance. Written by pathology experts Amy Valenciano, Rick Cowell, Theresa Rizzi, and Ronald Tyler, this concise reference will enhance your skills as you interpret blood smears and recognize hematological cellular response to inflammation, infection, and toxicity."--Provided by publisher.Includes bibliographical references and index.Online resource; title from e-book title screen (ScienceDirect platform, viewed August 18, 2016)."An illustrated guide to the morphology of blood cells, Atlas of Canine and Feline Peripheral Blood Smears covers patient assessment for common hematologic disorders and diseases in dogs and cats. Over 1,000 full-color photomicrographs depict abnormalities within each blood cell line, with multiple pictures of each morphologic abnormality and variations in their appearance. Written by pathology experts Amy Valenciano, Rick Cowell, Theresa Rizzi, and Ronald Tyler, this concise reference will enhance your skills as you interpret blood smears and recognize hematological cellular response to inflammation, infection, and toxicity."--Provided by publisher.General assessment -- Red blood cells -- White blood cells -- Platelets -- Hematopoietic neoplasia -- Extracellular organisms.Produced by the publisher.Held by CAPER-BC, Langara College.Elsevie
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