1,474 research outputs found
Interview with K.A. Hays
No full textK.A. Hays’ most recent book is Anthropocene Lullaby (February 2022, Carnegie Mellon). She is the author of three prior books of poetry: Windthrow (2017), Early Creatures, Native Gods (2012) and Dear Apocalypse (2009). Her poems appear widely in journals and have been selected for two editions of Best American Poetry. Born in Phoenixville, Pennsylvania, she earned an MFA from Brown University. She teaches Creative Writing at Bucknell University in Lewisburg, PA, and directs the Bucknell Seminar for Undergraduate Poets, a 3-week all-expenses paid summer writing retreat and conference for undergraduate poets from any university or college in the United States
Use of SNP markers to conserve genome-wide genetic diversity in livestock
No full text Conservation of genetic diversity in livestock breeds is important since it is, both within and between breeds, under threat. The availability of large numbers of SNP markers has resulted in new opportunities to estimate genetic diversity in more detail, and to improve prioritization of animals for conservation of genetic diversity. The aim of this thesis was to further explore the potential of SNP markers for estimation and conservation of genetic diversity within livestock breeds. This was evaluated analyzing Holstein cattle populations, genotyped with a commonly used 50k SNP chip. Genetic diversity was estimated with SNP markers and compared to genetic diversity estimated with pedigree information. Both methods could detect differences in overall genetic diversity, even between two closely related populations. With SNP markers, differences in genetic diversity at the chromosomal level could be identified as well. Subsequently, SNP markers and pedigree information were used to prioritize animals for conservation in a gene bank using optimal contributions. SNP based prioritization was slightly more effective than pedigree based information, both over the whole genome and at specific regions of the genome. We extended the optimal contribution method to simultaneously conserve a single allele at a specific frequency and maximize the overall genetic diversity conserved in a gene bank. The loss of overall genetic diversity was larger when the target frequency for animals conserved in the gene bank differed more from the original frequency in the population. It can be concluded that dense SNP data form a powerful tool for estimation and conservation of genetic diversity in livestock breeds. Although pedigree information gives a good representation of the overall genetic diversity, SNP markers can provide more detailed information about the genetic diversity over the genome. Especially for small populations, SNP markers can play an important role in conservation of unique alleles, while simultaneously minimizing the loss of genetic diversity at the rest of the genome. </p
Dier & de stad : factsheet voor het stedennetwerk - stadslandbouw
No full textIn deze factsheet ‘Dier & De stad’ laten we zien welke positieve effecten landbouwhuisdieren kunnen hebben op de stadsbewoners en hun omgeving, welke risico’s dit met zich mee brengt en hoe deze risico’s beperkt of zelfs voorkomen kunnen worden
Skin-Friction Measurements on Mathematically Generated Roughness in a Turbulent Channel Flow
No full textEngineering systems are affected by surface roughness, however, predicting frictional drag has proven to be challenging. The present work takes a systematic approach by generating and manufacturing surfaces roughness where surface statistics, such as rms, skewness and power-spectral density can be controlled. The frictional drag on these surfaces is measured in a turbulent channel flow facility
Perspectives of genomics for genetic conservation of livestock
No full textGenomics provides new opportunities for conservation genetics. Conservation genetics in livestock is based on estimating diversity by pedigree relatedness and managing diversity by choosing those animals that maximize genetic diversity. Animals can be chosen as parents for the next generation, as donors of material to a gene bank, or as breeds for targeting conservation efforts. Genomics provides opportunities to estimate diversity for specific parts of the genome, such as neutral and adaptive diversity and genetic diversity underlying specific traits. This enables us to choose candidates for conservation based on specific genetic diversity (e.g. diversity of traits or adaptive diversity) or to monitor the loss of diversity without conservation. In wild animals direct genetic management, by choosing candidates for conservation as in livestock, is generally not practiced. With dense marker maps opportunities exist for monitoring relatedness and genetic diversity in wild populations, thus enabling a more active management of diversity
Estimating genetic diversity across the neutral genome with the use of dense marker maps
No full textAbstract Background With the advent of high throughput DNA typing, dense marker maps have become available to investigate genetic diversity on specific regions of the genome. The aim of this paper was to compare two marker based estimates of the genetic diversity in specific genomic regions lying in between markers: IBD-based genetic diversity and heterozygosity. Methods A computer simulated population was set up with individuals containing a single 1-Morgan chromosome and 1665 SNP markers and from this one, an additional population was produced with a lower marker density i.e. 166 SNP markers. For each marker interval based on adjacent markers, the genetic diversity was estimated either by IBD probabilities or heterozygosity. Estimates were compared to each other and to the true genetic diversity. The latter was calculated for a marker in the middle of each marker interval that was not used to estimate genetic diversity. Results The simulated population had an average minor allele frequency of 0.28 and an LD (r2) of 0.26, comparable to those of real livestock populations. Genetic diversities estimated by IBD probabilities and by heterozygosity were positively correlated, and correlations with the true genetic diversity were quite similar for the simulated population with a high marker density, both for specific regions (r = 0.19-0.20) and large regions (r = 0.61-0.64) over the genome. For the population with a lower marker density, the correlation with the true genetic diversity turned out to be higher for the IBD-based genetic diversity. Conclusions Genetic diversities of ungenotyped regions of the genome (i.e. between markers) estimated by IBD-based methods and heterozygosity give similar results for the simulated population with a high marker density. However, for a population with a lower marker density, the IBD-based method gives a better prediction, since variation and recombination between markers are missed with heterozygosity.</p
International Research Roundtable “History of the Kazakh Statehood. On the 80th Anniversary of the Famous Researcher K.A. Pischulina” (December 24, 2014) »
No full textThis article contains a brief description of the International research conference. The author gives a brief description of the papers presented at the conference. The following reports were presented at the conference: K.Z. Uskenbay. “The Kazakh Statehood during the Late Middle Ages in the Scientific Biography of K.A. Pishchulina”; A. Daulethan. “Formation of Kazakh Culture in the Era of the Mongol Uluses (13th–16th centuries)”; N. Kenzheahmet. “The Kazakh Khanate in the Chinese Sources (15th–16th centuries)”; I.M. Mirgaleev. “Activities of the Centre for Research on the Golden Horde History (Sh.Marjani Institute of History, Academy of Sciences of the Republic of Tatarstan) Aimed at Studying New Sources”; K.U. Torlanbaeva. “Ancient and Medieval Kazakhstan in Migration Processes”; Zh.Zh. Zhenis. “Continuity of Statehood and Traditional Worldview in the Empire of Genghis Khan”; A.P. Ermuhamedova. “The Oghuz Role in World History”; N.A. Atygaev. “Early Stage in the History of Kazakh Khanate in the Works of K.A. Pischulina”
Quickscan van de gegevensverzameling voor duurzaamheid in de veehouderij
No full textUtilising monitoring for sustainability in breeding of farm animals
Quickscan van de gegevensverzameling voor duurzaamheid in de veehouderij
No full textUtilising monitoring for sustainability in breeding of farm animals
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