2,386 research outputs found
The Highest Principles:The Death and Rise of ‘First Philosophy’. An Introduction to Metaphysics
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Plastic Mortals and 21st Century Healthcare:An Introduction to Philosophical Anthropology
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Archives Reenergized: Using a Milestone Anniversary to Reinvigorate Interest in Your Collections
No full textThe Peirce College Library used the College's sesquicentennial anniversary to showcase its archive collection internally and externally,"July/August, 2015
Interactions between STAT3 and BART
No full textSignal transducers and activators of transcription (STATs) mediate cell proliferation, differentiation, and survival in immune responses, hematopoiesis, neurogenesis, and other biological processes. STAT3, for example, is involved in the epithelialmesenchymal transition during gastrulation, organogenesis, wound healing, and cancer progression. STAT activity is regulated by a variety of mechanisms, including nuclear translocation. To clarify the molecular mechanisms underlying the regulation of STAT activity, we performed yeast two-hybrid screening. Here we identified BART (Binder of ADP-ribosylation factor-like Two) as a novel STAT-binding partner. Importantly, we showed that BART is essential for the transcriptional activity and nuclear retention of STAT3. Furthermore, an effector of BART, ADP-ribosylation factor-like 2 (ARL2) was also involved in nuclear retention of STAT3. These results indicate that BART plays an essential role in the nuclear retention of STAT3 through interaction with ARL2
Marlin "Bart" Barton
No full textMarch 8, 2012, Ablah Library, Wichita State UniversityMarlin "Bart" Barton, award-winning author, reads from his newest book, The Cross Garden.WSU Libraries, Department of Englis
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