305,177 research outputs found
Nuovi materiali da risorse seconde: un framework per lo sviluppo e progettazione di materiali circolari
No full textIl contributo esplora sfide e opportunità legate all’adozione dei materiali circolari nel contesto produttivo italiano ed europeo. Tramite la revisione della letteratura scientifica e l’analisi di casi studio, la ricerca identifica i principali fattori chiave che ne influenzano lo sviluppo e la diffusione, ostacolandone la scalabilità. Come parte di una ricerca di dottorato nell’ambito del Material Design, si propone un framework di mappatura del processo di evoluzione dei materiali circolari lungo quattro macro-fasi: i) sperimentazione e caratterizzazione, ii) ottimizzazione e validazione, iii) consolidamento e accettazione; infine, iv) industrializzazione e istituzionalizzazione. Lo strumento proposto consente di a) comprenderne le dinamiche di crescita e di adozione industriale, b) supportare aziende e designer a superare le sfide operative e a progettare strategie per la scalabilità circolare, c) suggerire nuove direzioni di ricerca per la valorizzazione della materia circolare
La cultura dei materiali e il lato sensoriale del progetto / The material cultures and the sensory side of the project
No full textL’ambito della cultura dei materiali per il design, oggi, si presenta quale disciplina variegata e multiforme: tale contesto, infatti, è studiato attraverso metodi, metodologie e approcci differenti, appartenenti a scienze e saperi spesso anche distanti tra loro, quali discipline delle aree tecnico-scientifiche e discipline umanistiche. I materiali (per il progetto) sono infatti indagati principalmente da due tipi di conoscenze, la prima più tecnica e la seconda più estetico-sensoriale. L’articolo si focalizzerà su quest’ultima, porgendo particolare attenzione ai sensi del tatto, dell’udito e dell’olfatto, quali “strumenti” per il progettista per la progettazione corretta della loro user experience, della percezione, emozione e reazione che una persona prova quando si interfaccia con essi.
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Today, the field of the culture of materials for design is a variegated and multi-form discipline: this context, in fact, is investigated through different methods, methodologies and approaches, belonging to sciences and knowledge that are often very distant from each other, such as disciplines of technical-scientific areas and humanities. The materials (for the project) are, in fact, investigated mainly by two types of knowledge, a more technical one and a more aesthetic-sensorial one. The article will focus on the latter, paying particular attention to the senses of touch, hearing and smell, as “tools” for the designer looking for the correct design of their user experience, perception, emotion and reaction when interfacing with them
Asimmetrie informative in economia circolare. Un’investigazione di design nelle reti sociali digitali / Information Asymmetries in the Circular Economy. A Design Investigation in Digital Network Spaces
No full textIn digital spaces, communication about circularity is influenced by dynamics of cultural dominance and polarisation. This study analyses textual and visual traces on two case studies of digital platforms to understand the dynamics of collective circular memory. Through methods of Digital Design such as Data Visualization and Vanity Metrics, critical issues such as interpretative homogeneity on Wikipedia and the dominance of a few entries on Instagram emerge. The absence of diversified cultural representations limits the dissemination of structured and inclusive knowledge. The study emphasises the need for interdisciplinary and participatory communication models, highlighting spaces for project intervention to counter circular disinformation phenomena.*Negli spazi digitali, la comunicazione sulla circolarità è influenzata da dinamiche di dominanza culturale e polarizzazioni. Questo studio analizza tracce testuali e visive su due piattaforme digitali quali casi studio per comprendere le dinamiche della memoria circolare collettiva. Attraverso l’uso di metodi di Digital Design tra cui Data Visualization e Metriche di Vanità, emergono criticità quali l’omogeneità interpretativa su Wikipedia e il dominio di poche voci su Instagram. L’assenza di rappresentazioni culturali diversificate limita la diffusione di una conoscenza strutturata e inclusiva. Lo studio sottolinea la necessità di modelli di comunicazione interdisciplinari e partecipativi, evidenziando spazi d’intervento progettuale per contrastare fenomeni di disinformazione circolare
Inherited thrombophilia in infertile women: implication in unexplained infertility
No full textMany studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677 T) was found in 100 infertile women with unexplained infertility when compared with 200 control fertile women without an infertility history
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
The role of serum anti-Müllerian hormone (AMH) in the hormonal diagnosis of polycystic ovary syndrome.
No full textBackground: The study was performed to validate the threshold for anti-Müllerian hormone (AMH) that suggests the presence of polycystic ovaries in women with polycystic ovary syndrome (PCOS).
Methods: This prospective observational study included 59 infertile women: (A) 22 PCOS with hyperandrogenism (HA) and oligo-anovulation, (B) 15 suspected PCOS with either HA or oligo-anovulation and (C) 22 asymptomatic control women. The diagnosis of PCOS was made according to the NIH classification.
Results: For serum AMH and follicle number, respectively, the areas under the receiver operating characteristic curve (A versus C) were 0.97 and 0.93. The best compromise between specificity (95% and 91%) and sensitivity (95% and 82%) was obtained with threshold values of 33 pmol/l and 13 follicles, respectively. Using a serum AMH > 33 pmol/l as a surrogate for either HA or oligo-anovulation in group B would lead to the diagnosis of PCOS in seven (46.6%) patients from this group.
Conclusions: Our data confirms that the AMH assay has a high diagnostic potential, providing that an appropriate threshold is used. AMH measurement may be included as an ultimate diagnostic criterion for the diagnosis of PCOS when either HA or anovulation is missing and/or when no reliable antral follicle count can be obtained
Author, publisher and bookseller : a tripartite synergy in Nigerian book industry
No full textThis work is about the roles of Author, Publisher and Bookseller in Book development in
Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after
which it proceeded by defining who an author, a publisher, and a bookseller is and
expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in
the emerging Information Society. Furthermore, the various constraints to book
development were identified while the paper advised on how the Book Industry can be
further promoted in Nigeria. However, the paper concluded and made recommendations
on how the Book sector can help in enhancing scholarship in the country
Sequential low-dose step-up and step-down protocols with recombinant follicle-stimulating hormone in polycystic ovary syndrome: prospective comparison with step-down protocol.
No full textPURPOSE: To assess the differences in follicular development comparing two sequential low-dose step-up and step-down protocols (A: 37.5 IU/day, B: 75 IU/day) with a step-down protocol (C: 150 IU/day) using recombinant human follicle stimulating hormone (rFSH) in women with polycystic ovarian syndrome (PCOS).
METHODS: In this prospective observational comparative study, 60 PCOS women were treated with one of the three protocols for only one cycle.
RESULT(S): Monofollicular development was similar among the three protocols but the total number of follicles >10 mm in diameter was significantly lower in group A (1 ± 0.94 vs 6.3 ± 2.45 vs 8.6 ± 4.45; P = 0.001 A vs B; P < 0.001 A vs C). Cycle cancellation rate was higher in protocol A and in protocol C because of no ovarian response and excessive multifollicular development, respectively. The total amount of rFSH for complete cycle was significantly lower in protocol A (P = 0.02 A vs B; P = 0.007 A vs C). No mild or severe hyperstimulation syndrome (OHSS) was observed.
CONCLUSION(S): A and B protocols seem to be a more effective approach than the step-down protocol. In both groups, the pregnancy rate for started cycle was the same. Protocol A has allowed the development of a lower number of small follicles, single pregnancies, but an excessive number of cancelled cycles occurred. In protocol B no cycle cancellation occurred, though the total rFSH dosage was significantly higher than the protocol A and two twin pregnancies were observed
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