88 research outputs found
sj-doc-1-end-10.1177_11795514231203907 – Supplemental material for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes
No full textSupplemental material, sj-doc-1-end-10.1177_11795514231203907 for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes by Amir Babiker, Nancy Samir Elbarbary, Bothainah Alaqeel, Khalid Al Noaim, Saif Al Yaarubi, Dalia Al-Abdulrazzaq, Hessa Al-Kandari, Haya Alkhayyat, Rasha Odeh, Omer Babiker, Abdulsalam Abu-Libdeh, Amal Aljohani, Noof Al Abdul Salam, Fatima Al-Juailla, Emad Masuadi, Asma Deeb, Jill Weissberg-Benchell, Alice M. Gregory, Mohamed Hassanein and Ibrahim Al Alwan in Clinical Medicine Insights: Endocrinology and Diabetes</p
sj-doc-3-end-10.1177_11795514231203907 – Supplemental material for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes
No full textSupplemental material, sj-doc-3-end-10.1177_11795514231203907 for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes by Amir Babiker, Nancy Samir Elbarbary, Bothainah Alaqeel, Khalid Al Noaim, Saif Al Yaarubi, Dalia Al-Abdulrazzaq, Hessa Al-Kandari, Haya Alkhayyat, Rasha Odeh, Omer Babiker, Abdulsalam Abu-Libdeh, Amal Aljohani, Noof Al Abdul Salam, Fatima Al-Juailla, Emad Masuadi, Asma Deeb, Jill Weissberg-Benchell, Alice M. Gregory, Mohamed Hassanein and Ibrahim Al Alwan in Clinical Medicine Insights: Endocrinology and Diabetes</p
sj-docx-4-end-10.1177_11795514231203907 – Supplemental material for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes
No full textSupplemental material, sj-docx-4-end-10.1177_11795514231203907 for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes by Amir Babiker, Nancy Samir Elbarbary, Bothainah Alaqeel, Khalid Al Noaim, Saif Al Yaarubi, Dalia Al-Abdulrazzaq, Hessa Al-Kandari, Haya Alkhayyat, Rasha Odeh, Omer Babiker, Abdulsalam Abu-Libdeh, Amal Aljohani, Noof Al Abdul Salam, Fatima Al-Juailla, Emad Masuadi, Asma Deeb, Jill Weissberg-Benchell, Alice M. Gregory, Mohamed Hassanein and Ibrahim Al Alwan in Clinical Medicine Insights: Endocrinology and Diabetes</p
sj-doc-2-end-10.1177_11795514231203907 – Supplemental material for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes
No full textSupplemental material, sj-doc-2-end-10.1177_11795514231203907 for Lessons Learned From COVID-19 Lockdown: An ASPED/MENA Study on Lifestyle Changes and Quality of Life During Ramadan Fasting in Children and Adolescents Living With Type 1 Diabetes by Amir Babiker, Nancy Samir Elbarbary, Bothainah Alaqeel, Khalid Al Noaim, Saif Al Yaarubi, Dalia Al-Abdulrazzaq, Hessa Al-Kandari, Haya Alkhayyat, Rasha Odeh, Omer Babiker, Abdulsalam Abu-Libdeh, Amal Aljohani, Noof Al Abdul Salam, Fatima Al-Juailla, Emad Masuadi, Asma Deeb, Jill Weissberg-Benchell, Alice M. Gregory, Mohamed Hassanein and Ibrahim Al Alwan in Clinical Medicine Insights: Endocrinology and Diabetes</p
Clinical characterization of pediatric supratentorial tumors and prediction of pituitary insufficiency in two tertiary centers in Saudi Arabia
No full textBackground: Post-operative pituitary insufficiency (PI) occurs in children with supra-tentorial tumors (STT) because of surgery or the mass effect of the tumor. We assessed the prevalence and clinical characteristics of STTs and predicted postoperative PI in our patients. Methods: This retrospective cohort study included children who underwent surgery for STT in two tertiary hospitals in Saudi Arabia (2009-2019). We focused on clinical, radiological, and histopathological features of STTs. We also used a linear regression model to predict post-operative PI. Results: The study included 55 children (1-18 years, mean: 9.5 ± 4.9 years, 32 [54%] females) with an initial presentation of STT that required surgery excluding recurrent episodes. The calculated period prevalence of STT was 18.2%, and the prevalence of postoperative PI was 58.2% (n = 32/55). The most common symptoms were headache and visual disturbances, and 20% patients had preoperative symptoms of PI. Baseline preoperative investigations for PI were performed in 60% of patients, and dynamic tests were conducted in only seven patients. A residual cortisol deficiency was presumed in 24 (43.7%) patients and 18 (32.7%) patients who developed central diabetes insipidus (DI) post-operatively. Overall, the brain imaging correlated well with the histopathological diagnosis (kappa = 0.48; P < .001). Craniopharyngioma (n = 15/55, 27.3%) was the commonest STT. Predictive factors for a postoperative residual PI included age (10.9 ± 4.8 years; p-value = .027), female gender (p-value = .016 [OR = 8.31; 95% CI (1.48-46.71)], presentation with headache (P value = .039 [OR = 9.27; 95% CI (1.12-76.72)]), and visual disturbances (p-value = .044 [OR = 5.07; 95% CI (1.04-24.61)]. Conclusion: STTs commonly occurred in our study population, and females were more prone to develop a residual PI. On-time surveillance of an intact endocrine system during the perioperative period is essential for the prediction and early management of PI
Postoperative intensive care management and residual endocrinopathy of pediatric supratentorial brain tumors: a retrospective cohort study
No full textObjectives Endocrinopathy can occur as a postoperative sequel in children treated for supratentorial tumors (STTs). We assessed prediction of a residual hypothalamic/pituitary insufficiency (HPI) in these patients and factors associated with prolonged length of hospital stay (LOS). Methods This is a retrospective cohort study of children who had surgery for STTs in two tertiary centers in Saudi Arabia (2009-2019). We assessed PICU postoperative management and risk of HPI. Data were analyzed using SPSS V24.0 and a logistic regression model for a prediction of a prolonged LOS. Results Data included 55 children (1-18 years, mean 9.5 +/- 4.9 years) who required STT surgeries, 32 (54%) females. Craniopharyngioma (27.3%) was the commonest STTs and 20% of patients had initial symptoms of HPI. PICU management included the use of different types of intravenous fluids (IVFs) and medications such as steroids and desmopressin (DDAVP). An early postoperative DI was reported in 21.8% (n=12/55). Residual HPI included 24 (43.6%) presumed cortisol deficient and 18 (32.7%) central DI patients. Risk factors for postoperative HPI were female gender, age <6 years, headache and preoperative pituitary symptoms. LOS (Median=25.5 +/- 12.2 days) was significantly prolonged in patients who required two or more doses of DDAVP [B=13; 95% CI= (1.7-24.3) days] and reduced in patients who had suspected preoperative HPI [B=-19.6; 95% CI= (-31.1, -8.2) days]. Conclusions Prediction of postoperative HPI in pediatric STTs enhances an early initiation of treatment in PICU and reduces LOS. A meticulous use of IVF and medications supervised by a multidisciplinary team is essential for a favorable outcome
Use of child restraint system and patterns of child transportation in Riyadh, Saudi Arabia
No full textTwo-sample Bayesian nonparametric goodness-of-fit test
No full textTesting the difference between two data samples is of a particular interest in statis-tics. Precisely, given two samplesX = X1,..., Xm1 i.i.d. ∼ F andY = Y1,..., Ym2 i.i.d.∼ G, with F and G being unknown continuous cumulative distribution functions, we wish to test the null hypothesis H0: F = G. In this paper, we propose an effective and convenient Bayesian nonparametric approach to assess the equality of two unknown dis-tributions. The method is based on the Kolmogorov distance and approximate samples from the Dirichlet process centered at the standard normal distribution and a concentra-tion parameter 1. Our results show that the proposed test is robust with respect to any prior specification of the Dirichlet process. We provide simulated examples to illustrat
Use of child restraint system and patterns of child transportation in Riyadh, Saudi Arabia.
No full textObjectiveChild restraint system (CRS) is designed to protect children from injury during motor vehicle crash (MVC). However, there is no regulation or enforcement of CRS use in Saudi Arabia. This study estimated the prevalence of CRS use and identified patterns of child transportation in Riyadh, Saudi Arabia.MethodsIn this cross-sectional study, a self-administered questionnaire was distributed across Riyadh targeting families who drove with children aged less than 5 years. The questionnaire inquired about CRS availability, patterns of child transportation if a CRS was unavailable, seat belt use by the driver and adult passengers, and the perception of CRS.ResultsOf 385 respondents, only 36.6% reported the availability of a CRS (95% CI: 31.8-41.7%), with only half of those reported consistent use 74 (52.2%). Nearly 30% of all children aged less than 5 years were restrained during car journeys. Sitting on the lap of an adult passenger on the front seat was the most common pattern of child transportation (54.5%). Approximately 13.5% of respondents were involved in an MVC while driving with children; 63.5% of these children were unprotected by any safety system. Seat belt use by drivers was low, with only 15.3% reporting constant use.ConclusionThe prevalence of CRS use in Riyadh is low, and safety practices are seldom used by drivers and passengers. In addition to legal enforcement of CRS use, implementation of a child transportation policy with age-appropriate height and weight specifications is imperative
- …
