23 research outputs found

    Correction to

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    The article “Intermittent levosimendan infusion in ambulatory patients with end‑stage heart failure: a systematic review and meta‑analysis of 984 patients”, written by Hagar Elsherbini, Osama Soliman, Casper Zijderhand, Mattie Lenzen, Sanne E. Hoeks, Rasha Kaddoura, Mohamed Izham5, Abdulaziz Alkhulaifi, Amr S. Omar, and Kadir Caliskan, was originally published electronically on the publisher’s internet portal on 11 April 2021 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 10 June 2021 to</p

    Laser and radiofrequency-induced hyperthermia treatment via gold-coated magnetic nanocomposites

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    Alsayed AM Elsherbini1, Mahmoud Saber2, Mohamed Aggag2, Ahmed El-Shahawy2, Hesham AA Shokier11National Institute of Laser Enhanced Science, 2Children&amp;#39;s Cancer Hospital, Cairo, EgyptIntroduction: The current radiofrequency ablation technique requires invasive needle placement. On the other hand, most of the common photothermal therapeutic methods are limited by lack of accuracy of targeting. Gold and magnetic nanoparticles offer the potential to heat tumor tissue selectively at the cellular level by noninvasive interaction with laser and radiofrequency.Methods: Gold nanospheres and gold-coated magnetic nanocomposites were used for inducing hyperthermia to treat subcutaneous Ehrlich carcinoma implanted in female mice.Results: In mice treated with gold nanospheres, tumors continued to grow but at a slow rate. In contrast, more than 50% of the tumors treated with gold-coated magnetic nanocomposites completely disappeared.Conclusion: This simple and noninvasive method shows great promise as a technique for selective magnetic photothermal treatment.Keywords: laser, hyperthermia, gold magnetic nanocomposites, Ehrlich carcinom

    The New Kumaraswamy Kumaraswamy Family of Generalized Distributions with Application

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    Finding the best fitted distribution for data set becomes practically an important problem in world of data sets so that it is useful to use new families of distributions to fit more cases or get better fits than before.  In this paper, a new generating family of generalized distributions so called the Kumaraswamy - Kumaraswamy (KW-KW) family is presented. Four important common families of distributions are illustrated as special cases from the KW KW family. Moments, probability weighted moments, moment generating function, quantile function, median, mean deviation, order statistics and moments of order statistics are obtained. Parameters estimation and variance covariance matrix are computed using maximum likelihood method. A real data set is used to illustrate the potentiality of the KW KW weibull distribution (which derived from the kw kw family) compared with other distributions

    Selection of appropriate time scale with Boruta algorithm for regional drought monitoring using multi-scaler drought index

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    Spatial distribution of drought plays key role specifically in hydrological research. Drought is a complex stochastic natural hazard caused by prolonging shortage of rainfall and available water resources. The multi-scalar drought indices (based on probability distribution) are commonly used for making effective drought mitigation policies. In addition, the multi-scalar drought indices have great extent of the inaccurate determination of drought classes due to its probabilistic nature. However, the interpretation and applicability of various time scales are cumbersome for multi-scalar drought in various meteorological stations at a particular region. In this regards, accurate estimation and continuous monitoring of future drought at regional level requires a more appropriate and important time scale with respect to regions under study. In this study, we aimed to investigate the appropriate time scale for multi-scalar drought indices by using geo-reference points of meteorological stations. We used Boruta algorithm with two random forest adapters of machine learning algorithms for regionalized optimization of drought monitoring time scale. We explored the appropriate time scale for the Standardized Precipitation Temperature Index (SPTI) of 52 meteorological stations that are located across Pakistan. Results show that the significant importance of SPTI-1 (1-month time scale) for further spatial and temporal studies. That is, being high ranked and prominence, SPTI-1 has the ability to capture the characteristics of all other time scales that are in some circumstances applicable for drought characterization and classification

    A new spatiotemporal two-stage standardized weighted procedure for regional drought analysis

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    Drought is a complex phenomenon that occurs due to insufficient precipitation. It does not have immediate effects, but sustained drought can affect the hydrological, agriculture, economic sectors of the country. Therefore, there is a need for efficient methods and techniques that properly determine drought and its effects. Considering the significance and importance of drought monitoring methodologies, a new drought assessment procedure is proposed in the current study, known as the Maximum Spatio-Temporal Two-Stage Standardized Weighted Index (MSTTSSWI). The proposed MSTTSSWI is based on the weighting scheme, known as the Spatio-Temporal Two-Stage Standardized Weighting Scheme (STTSSWS). The potential of the weighting scheme is based on the Standardized Precipitation Index (SPI), Standardized Precipitation Evapotranspiration Index (SPEI), and the steady-state probabilities. Further, the STTSSWS computes spatiotemporal weights in two stages for various drought categories and stations. In the first stage of the STTSSWS, the SPI, SPEI, and the steady-state probabilities are calculated for each station at a 1-month time scale to assign weights for varying drought categories. However, in the second stage, these weights are further propagated based on spatiotemporal characteristics to obtain new weights for the various drought categories in the selected region. The STTSSWS is applied to the six meteorological stations of the Northern area, Pakistan. Moreover, the spatiotemporal weights obtained from STTSSWS are used to calculate MSTTSSWI for regional drought characterization. The MSTTSSWI may accurately provide regional spatiotemporal characteristics for the drought in the selected region and motivates researchers and policymakers to use the more comprehensive and accurate spatiotemporal characterization of drought in the selected region.Validerad;2022;Nivå 2;2022-05-02 (joosat);Funder: Deanship of Scientific Research at King Saud University (1435-075)</p

    Measuring the ecological footprint of inbound and outbound tourists: Evidence from a panel of 35 countries

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    The ecological footprint of tourism is imperative to assess for United Nation’s environmental sustainable agenda that is provoked for healthy visitation of tourists without damaging natural environment. This would ultimately reap economic and environmental benefts to sustained international tourism. This study examined the relationship between international tourism indicators, air pollutants, and ecological biodiversity underlying the premises of environmental Kuznets curve in the panel of 35 tourists-induced countries for the period of 1995–2016. The study used panel fxed efect and panel twostage least square regression technique for robust inferences. The results confrmed the following key points, i.e., (1) the U-shaped relationship found between inbound tourists and mono-nitrogen oxide (NOx), where inbound tourists initially do not emanate the NOx emissions, while at the later stages, the level of NOx emissions substantially raises the required strong policy intervention to reduce emissions and provide tourists safe and healthy destinations, (2) inbound tourists linked with the biodiversity loss, and it increases carbon dioxide (CO2) emissions and greenhouse gas (GHG) emissions in a panel of potential habitat area, while it decreases NOx and SO2 emissions, (4) international tourists’ departure exercised the ‘rebound efect’ on the ecosystem and air pollutants across countries, (5) there is a monotonic increasing relationship between outbound tourists and ecological footprint, while there is a fat/no relationship between outbound tourists, NOx, CO2, SO2, and GHG emissions, and (6) the food management practices supported the ecological diversity, and it reduces the carbon ‘foodprint,’ while it substantially increases SO2 emissions in outbound tourists’ model. The study emphasized the need for sustainable tourism infrastructure that conserves our natural environment and reduces climatic variability across the globe

    Use of condensate drain to pre-cool the inlet air to the condensers: A technique to improve the performance of split air-conditioning units

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    In hot ambient conditions, split air-conditioning (AC) systems experience a drop in their coefficient of performance and an increase in power consumption due to the direct relationship between the condensation temperature of the unit and the prevailing ambient temperature. In this work, the enhancement in the COP and the reduction in power consumption for a split AC unit are evaluated when a direct water spray evaporative cooling system is used. The study focuses on minimizing the amount of water needed to cool the condenser by utilizing the wasted water from the condensate drain, synchronizing the water injection with ON-OFF compressor operation, and determining the optimal hourly periods for the injection system to achieve a reduction in energy consumption. The objectives of this work are threefold. The first objective is to conduct experiments inside an environmental chamber to determine the effectiveness of the evaporative cooling system at different ambient conditions and to derive correlations that predict the outlet air conditions and the water consumption. The second objective is to develop an integrated mathematical model to simulate the performance of the evaporatively cooled split AC system in a controlled space under certain operational conditions (using steady-state performance data supplied by the manufacturer and taking into account the transient effect during the ON-OFF compressor cycling) and to experimentally validate this model. The third and final objective is to evaluate the model under real environment conditions for a case study where the thermal conditions and energy demand of a typical office space in Beirut during three months (June, August, and October) are investigated and where the sufficiency of drain water is the limiting factor. The simulation results have shown that the drain water would be sufficient in October only, resulting in 5.3percent energy saving throughout the whole day. On the other hand, the synchronized spray of water is found to last for six operating hours in a June day and eight hours in August; this results in a total daily reduction in the consumed energy of 5percent in June and 4.5percent in August. © 2012 2012 ASHRAE.Akbari H., 2002, ENVIRON POLLUT, V116, P119; ASHRAE, 2007, 6222007 ASHRAE; Chen H, 2008, ENERG CONVERS MANAGE, V49, P1416, DOI 10.1016-j.enconman.2007.12.024; DOE, 1982, DOE 2 ENG MAN VERS 2; ElSherbini AI, 2010, ENERG BUILDINGS, V42, P1948, DOI 10.1016-j.enbuild.2010.05.031; Garde F., 1997, P CLIMA 2000 C AUG 3; Ghaddar N., 1998, INT J ENERG RES, V32, P523; Hajidavalloo E, 2007, APPL THERM ENG, V27, P1937, DOI 10.1016-j.applthermaleng.2006.12.014; Hajidavalloo E, 2010, INT J REFRIG, V33, P982, DOI 10.1016-j.ijrefrig.2010.02.001; Henderson HI, 1996, ASHRAE TRAN, V102, P266; Hwang YH, 2001, INT J REFRIG, V24, P238, DOI 10.1016-S0140-7007(00)00022-0; Kapadia RG, 2009, HVACandR RES, V15, P617, DOI 10.1080-10789669.2009.10390854; Laret L., 1980, P 7 INT C HEAT AIR C; Lee WL, 2008, ENERG BUILDINGS, V40, P1456, DOI 10.1016-j.enbuild.2008.02.009; Mara TA, 2005, J SOL ENERG-T ASME, V127, P294, DOI 10.1115-1.1862267; ONEAL DL, 1991, ASHRAE TRAN, V97, P316; Techarungpaisan P, 2007, ENERG CONVERS MANAGE, V48, P1222, DOI 10.1016-j.enconman.2006.10.012; Waly M, 2005, INT J ENERG RES, V29, P781, DOI 10.1002-er.1091; Yu FW, 2010, APPL ENERG, V87, P1198, DOI 10.1016-j.apenergy.2009.08.02311

    Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

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    none5549Background: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Methods: This was a patient-level, comparative analysis of two, international prospective cohort studies: one before the pandemic (January-October 2019) and the second during the SARS-CoV-2 pandemic (local emergence of COVID-19 up to 19 April 2020). Both included patients undergoing elective resection of an intra-abdominal cancer with curative intent across five surgical oncology disciplines. Patient selection and rates of 30-day postoperative pulmonary complications were compared. The primary outcome was 30-day postoperative mortality. Mediation analysis using a natural-effects model was used to estimate the proportion of deaths during the pandemic attributable to SARS-CoV-2 infection. Results: This study included 7402 patients from 50 countries; 3031 (40.9 per cent) underwent surgery before and 4371 (59.1 per cent) during the pandemic. Overall, 4.3 per cent (187 of 4371) developed postoperative SARS-CoV-2 in the pandemic cohort. The pulmonary complication rate was similar (7.1 per cent (216 of 3031) versus 6.3 per cent (274 of 4371); P = 0.158) but the mortality rate was significantly higher (0.7 per cent (20 of 3031) versus 2.0 per cent (87 of 4371); P < 0.001) among patients who had surgery during the pandemic. The adjusted odds of death were higher during than before the pandemic (odds ratio (OR) 2.72, 95 per cent c.i. 1.58 to 4.67; P < 0.001). In mediation analysis, 54.8 per cent of excess postoperative deaths during the pandemic were estimated to be attributable to SARS-CoV-2 (OR 1.73, 1.40 to 2.13; P < 0.001). Conclusion: Although providers may have selected patients with a lower risk profile for surgery during the pandemic, this did not mitigate the likelihood of death through SARS-CoV-2 infection. Care providers must act urgently to protect surgical patients from SARS-CoV-2 infection.openMcLean, K A; Kamarajah, S K; Chaudhry, D; Gujjuri, R R; Raubenheimer, K; Trout, I; Al Ameer, E; Creagh-Brown, B; Harrison, E M; Nepogodiev, D; Roslani, A C; Li, E; Pata, F; Ramos-De la Medina, A; van Ramshorst, G H; Sayyed, R; Simoes, J; Smart, N; Bhangu, A; Glasbey, James C; Khaw, R A; Ahmed, W; Akhbari, M; Baker, D; Borakati, A; Mills, E; Murray, V; Thavayogan, R; Yasin, I; Glasbey, J; Ridley, W; Sarrami, M; Zhang, G; Egoroff, N; Pockney, P; Richards, T; Edwards, M; Lee, M; Pinkney, T; Pearse, R; Vohra, R; Sohrabi, C; Jamieson, A; Nguyen, M; Rahman, A; English, C; Tincknell, L; Kakodkar, P; Kwek, I; Punjabi, N; Burns, J; Varghese, S; Erotocritou, M; McGuckin, S; Vayalapra, S; Dominguez, E; Moneim, J; Bhatia, S; Kouli, O; Salehi, M; Tan, H L; Yoong, A; Zhu, L; Seale, B; Nowinka, Z; Patel, N; Chrisp, B; Harris, J; Maleyko, I; Muneeb, F; Gough, M; James, C E; Skan, O; Chowdhury, A; Rebuffa, N; Khan, H; Down, B; Fatimah, Hussain Q; Siaw-Acheampong, K; Benson, R A; Bywater, E; Dawson, B E; Evans, J P; Heritage, E; Jones, C S; Khatri, C; Keatley, J M; Knight, A; Lawday, S; Mann, H S; Marson, E J; Mckay, S C; Mills, E C; Pellino, G; Picciochi, M; Taylor, E H; Tiwari, A; Simoes, J F F; Trout, I M; Venn, M L; Wilkin, R J W; Smart, N J; Minaya-Bravo, A; Gallo, G; Moug, S; Di Saverio, S; Vallance, A; Vimalchandran, D; Griffiths, E A; Evans, R P T; Townend, P; Roberts, K; McKay, S; Isaac, J; Satoi, S; Edwards, J; Coonar, A S; Marchbank, A; Caruana, E J; Layton, G R; Patel, A; Brunelli, A; Ford, S; Desai, A; Gronchi, A; Fiore, M; Almond, M; Tirotta, F; Dumitra, S; Kolias, A; Price, S J; Fountain, D M; Jenkinson, M D; Hutchinson, P; Marcus, H J; Piper, R J; Lippa, L; Servadei, F; Esene, I; Freyschlag, C; Neville, I; Rosseau, G; Schaller, K; Demetriades, A K; Robertson, F; Alamri, A; Shaw, R; Schache, A G; Winter, S C; Ho, M; Nankivell, P; Rey Biel, J; Batstone, M; Ganly, I; Vidya, R; Wilkins, A; Singh, J K; Thekinkattil, D; Sundar, S; Fotopoulou, C; Leung, E; Khan, T; Chiva, L; Sehouli, J; Fagotti, A; Cohen, P; Gutelkin, M; Ghebre, R; Konney, T; Pareja, R; Bristow, R; Dowdy, S; Rajkumar, S T S; Ng, J; Fujiwara, K; Stewart, G D; Lamb, B; Narahari, K; McNeill, A; Colquhoun, A; McGrath, J; Bromage, S; Barod, R; Kasivisvanathan, V; Klatte, T; Abbott, T E F; Abukhalaf, S; Adamina, M; Ademuyiwa, A O; Agarwal, A; Akkulak, M; Alameer, E; Alderson, D; Alakaloko, F; Albertsmeiers, M; Alser, O; Alshaar, M; Alshryda, S; Arnaud, A P; Magne Augestad, K; Ayasra, F; Azevedo, J; Bankhead-Kendall, B K; Barlow, E; Beard, D; Blanco-Colino, R; Brar, A; Breen, K A; Bretherton, C; Lima Buarque, I; Burke, J; Chaar, M; Chakrabortee, S; Christensen, P; Cox, D; Cukier, M; Cunha, M F; Davidson, G H; Di Saverio, S; Drake, T M; Edwards, J G; Elhadi, M; Emile, S; Farik, S; Fitzgerald, E J; Garmanova, T; Ghosh, D; Mendonça Ataíde Gomes, G; Grecinos, G; Gründl, M; Halkias, C; Hisham, I; Hutchinson, P J; Hwang, S; Isik, A; Jonker, P; Kaafarani, H M A; Keller, D; Kruijff, S; Lawani, I; Lederhuber, H; Leventoglu, S; Litvin, A; Loehrer, A; Löffler, M W; Aguilera Lorena, M; Marta Modolo, M; Major, P; Martin, J; Mashbari, H N; Mazingi, D; Metallidis, S; Mohan, H M; Moore, R; Moszkowicz, D; Ng-Kamstra, J S; Maimbo, M; Negoi, I; Niquen, M; Ntirenganya, F; Olivos, M; Oussama, K; Outani, O; Parreno-Sacdalanm, M; Jose Perez Rivera, C; Pinkney, T D; van der Plas, W; Qureshi, A; Radenkovic, D; Rutegård, M; Segura-Sampedro, J J; Santos, I; Schache, A; Schnitzbauer, A A; Seyi-Olajide, J O; Sharma, N; Shu, S; Soreide, K; Spinelli, A; Sund, M; Tabiri, S; Tsoulfas, G; Vimalachandran, D; Warren, O J; Wedderburn, D; Wright, N; Allemand, C; Boccalatte, L; Figari, M; Lamm, M; Larrañaga, J; Marchitelli, C; Noll, F; Odetto, D; Perrotta, M; Saadi, J; Zamora, L; Alurralde, C; Caram, E L; Eskinazi, D; Mendoza, J P; Usandivaras, M; Badra, R; Esteban, A; García, J S; García, P M; Gerchunoff, J I; Lucchini, S M; NIgra, M A; Vargas, L; Hovhannisyan, T; Stepanyan, A; Gould, T; Gourlay, R; Griffiths, B; Gananadha, S; McLaren, M; Cecire, J; Joshi, N; Salindera, S; Sutherland, A; Ahn, J H; Charlton, G; Chen, S; Gauri, N; Hayhurst, R; Jang, S; Jia, F; Mulligan, C; Yang, W; Ye, G; Zhang, H; Ballal, M; Gibson, D; Hayne, D; Moss, J; Viswambaram, P; Vo, U G; Bennetts, J; Bright, T; Brooke-Smith, M; Fong, R; Gricks, B; Lam, Y H; Ong, B S; Szpytma, M; Watson, D; Bagraith, K; Caird, S; Chan, E; Dawson, C; Ho, D; Jeyarajan, E; Jordan, S; Lim, A; Nolan, G J; Oar, A; Parker, D; Puhalla, H; Quennell, A; Rutherford, L; Von Papen, M; Wullschleger, M; Blatt, A; Cope, D; Fenton, M; Gani, J; Lott, N; Shugg, N; Elliott, M; Phung, D; Phan, D; Townend, D; Bong, C; Gundara, J; Frankel, A; Bowman, S; Guerra, G R; Bolt, J; Buddingh, K; Dudi-Venkata, N N; Jog, S; Kroon, H M; Sammour, T; Smith, R; Stranz, C; Lah, K; McGahan, W; Mitchell, D; Morton, A; Pearce, A; Roberts, M; Sheahan, G; Swinson, B; Alam, N; Banting, S; Chong, L; Choong, P; Clatworthy, S; Foley, D; Fox, A; Hii, M W; Knowles, B; Mack, J; Read, M; Rowcroft, A; Ward, S; Wright, G; Lanner, M; Königsrainer, I; Bauer, M; Kafka, M; Messner, F; Öfner, D; Tsibulak, I; Emmanuel, K; Grechenig, M; Gruber, R; Harald, M; Öhlberger, L; Presl, J; Wimmer, A; Namazov, İ; Samadov, E; Barker, D; Boyce, R; Corbin, S; Doyle, A; Eastmond, A; Gill, R; Haynes, A; Millar, S; O’Shea, M; Padmore, G; Paquette, N; Phillips, E; St, John S; Walkes, K; Flamey, N; Pattyn, P; Oosterlinck, W; Van den Eynde, J; Van den Eynde, R; Gatti, A; Nardi, C; Oliva, R; De Cicco, R; Cecconello, I; Gregorio, P; Pontual, Lima L; Ribeiro, Junior U; Takeda, F; Terra, R M; Sokolov, M; Kidane, B; Srinathan, S; Boutros, M; Caminsky, N; Ghitulescu, G; Jamjoum, G; Moon, J; Pelletier, J; Vanounou, T; Wong, S; Kouyoumdjian, A; Johnston, B; Russell, C; Demyttenaere, S; Garfinkle, R; Abou-Khalil, J; Nessim, C; Stevenson, J; Heredia, F; Almeciga, A; Fletcher, A; Merchan, A; Puentes, L O; Mendoza, Quevedo J; Bačić, G; Karlović, D; Kršul, D; Zelić, M; Luksic, I; Mamic, M; Bakmaz, B; Ćoza, I; Dijan, E; Katusic, Z; Mihanovic, J; Rakvin, I; Frantzeskou, K; Gouvas, N; Kokkinos, G; Papatheodorou, P; Pozotou, I; Stavrinidou, O; Yiallourou, A; Martinek, L; Skrovina, M; Szubota, I; Žatecký, J; Javurkova, V; Klat, J; Avlund, T; Harbjerg, J L; Iversen, L H; Kjaer, D W; Kristensen, H Ø; Mekhael, M; Ebbehøj, A L; Krarup, P; Schlesinger, N; Smith, H; Abdelsamed, A; Azzam, A Y; Salem, H; Seleim, A; Abdelmajeed, A; Abdou, M; Abosamak, N E; Sayed, M A L; Ashoush, F; Atta, R; Elazzazy, E; Elhoseiny, M; Elnemr, M; Elqasabi, M S; Elsayed Hewalla, M E; Elsherbini, I; Essam, E; Eweda, M; Ghallab, I; Hassan, E; Ibrahim, M; Metwalli, M; Mourad, M; Qatora, M S; Ragab, M; Sabry, A; Saifeldin, H; Mesbah, Mohamed; Saleh Elkaffas, M; Samih, A; Samir, Abdelaal A; Shehata, S; Shenit, K; Attia, D; Kamal, N; Osman, N; Abbas, A M; Abd Elazeem, H A S; Abdelkarem, M M; Alaa, S; Ali, A K; Ayman, A; Azizeldine, M G; Elkhayat, H; Melghazaly, S; Monib, F A; Nageh, M A; Saad, M M; Salah, M; Shahine, M; Yousof, E A; Youssef, A; Eldaly, A; ElFiky, M; Nabil, A; Amira, G; Sallam, I; Sherief, M; Sherif, A; Abdelrahman, A; Aboulkassem, H; Ghaly, G; Hamdy, R; Morsi, A; Sherif, G; Abdeldayem, H; Abdelkader, Salama I; Balabel, M; Fayed, Y; Sherif, A E; Bekele, D; Kauppila, J; Sarjanoja, E; Helminen, O; Huhta, H; Kauppila, J H; Beyrne, C; Jouffret, L; Lugans, L; Marie-Macron, L; Chouillard, E; De Simone, B; Bettoni, J; Dakpé, S; Devauchelle, B; Lavagen, N; Testelin, S; Boucher, S; Breheret, R; Gueutier, A; Kahn, A; Kün-Darbois, J; Barrabe, A; Lakkis, Z; Louvrier, A; Manfredelli, S; Mathieu, P; Chebaro, A; Drubay, V; El amrani, M; Eveno, C; Lecolle, K; Legault, G; Martin, L; Piessen, G; Pruvot, F R; Truant, S; Zerbib, P; Ballouhey, Q; Barrat, B; Laloze, J; Salle, H; Taibi, A; Usseglio, J; Bergeat, D; Merdrignac, A; Le, Roy B; Le, B; Perotto, L O; Scalabre, A; Aimé, A; Ezanno, A; Malgras, B; Bouche, P; Tzedakis, S; Cotte, E; Glehen, O; Kepenekian, V; 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