3,573 research outputs found
Zhong liu fa sheng zhong you ai ji yin he yi ai ji yin yin qi de xi bao xin hao zhuan dao de yi chang
Zhong, Lan.Thesis Ph.D. Chinese University of Hong Kong 2014.Includes bibliographical references (leaves 122-154).Abstracts also in Chinese.Title from PDF title page (viewed on 24, October, 2016).Zhong, Lan
Depression in general practice : underrecognition? Overtreatment? Adequate care!
Dit proefschrift geeft een optimistisch beeld van de huidige zorg voor depressieve patiënten in de huisartsenpraktijk i.v.m. eerdere literatuur en mediaberichten. We concluderen dat, de zorg voor depressieve patiënten in de eerste lijn in het algemeen adequaat is, d.w.z. in overeenstemming met aanbevelingen uit geldende richtlijnen.
Ruim twee-derde van de depressieve patiënten werd door de huisarts herkend. Patiënten die psychische problemen met de huisarts bespraken, met meer depressieve symptomen en met tevens een angststoornis werden beter herkend. Het atypische symptoom toegenomen eetlust leidde tot slechtere herkenning.
58% van de depressieve patiënten werd verwezen voor psychologische of psychiatrische zorg. Huisartsen hielden de aanbevelingen voor verwijzing uit de richtlijn hierbij in het oog, patiënten met voorkeur voor psychotherapie, met chronische depressie of suïcidale neigingen werden vaker verwezen.
Ook behandeling met antidepressiva schrijven huisartsen volgens de richtlijn voor. Slechts bij 5,4% van de antidepressiva-gebruikers was sprake van overbehandeling. Bovendien was meer dan de helft van deze overbehandelde patiënten met een goede reden gestart, maar te lang doorbehandeld.
Uit een literatuur-review concludeerden wij dat aanbevelingen voor antidepressiva-gebruik gebaseerd zijn op voldoende bewijs v.w.b. acute behandeling en preventie van terugval gedurende enkele maanden, maar niet voor langdurige onderhoudsbehandeling.
Aanbevelingen voor onderhoudsbehandeling worden ook minder goed gevolgd. Het zijn niet, zoals de richtlijn voorschrijft, patiënten met een chronische of recidiverende depressie die onderhoudsbehandeling krijgen. Wel lijken het patiënten met een slechtere prognose: patiënten met tevens een angststoornis of dysthyme stoornis (langdurige ‘milde’ depressie), patiënten die naast antidepressiva ook kalmerende middelen gebruikten en met recente psychiatrische contacten.
Overall this thesis gives an optimistic picture of current care for depressed patients in primary care compared to previous literature and media reports. We conclude that, in general, the care for depressed patients in primary care is in most cases adequate, i.e. in accordance with ruling guideline recommendations.
The general practitioner recognized over two-thirds of depressed patients. Patients discussing psychological problems with the general practitioner, those with more depressive symptoms and with a concurrent anxiety disorder were better recognized. The atypical symptom increased appetite led to worse recognition.
58% of depressed patients were referred for psychological or psychiatric care. General practitioners took guideline recommendations into account in referring; patients with preference for psychotherapy, chronic depression or suicidal tendency were referred more often.
Treatment with antidepressants was also prescribed according to guideline recommendations. In only 5.4% of antidepressant users it could be called overtreatment. Furthermore, over half of these overtreated patients started with a good reason, but were treated too long according to guideline recommendations.
From review of the literature we conclude that guideline recommendations for antidepressant treatment are thoroughly evidence-based for acute treatment and relapse prevention during several months, but not for maintenance treatment.
Recommendations for maintenance treatment are also less often followed. Maintenance users are not, as the guideline prescribes, patients with chronic or recurrent depression. It does however seem that maintenance antidepressant users are those with a worse prognosis such as patients with comorbid dysthymia or anxiety and patients also receiving sedatives or patients with recent psychiatric contacts.
The etiology of esophageal cancer in high- and low- risk areas of Jiangsu province, China
[Background]Esophageal cancer (EC) remains one of the most common and fatal malignancies worldwide. The geographic variation in EC occurrence is striking, and China is an area with one of the highest incidences of EC. A number of epidemiological studies have been conducted toward EC in the past decades, results suggested that tobacco smoking, alcohol drinking, unhealthy dietary factors and chronic injuries of the esophageal mucosa are important in the development of this disease. Genetic polymorphisms in enzymes involved in metabolism of carcinogens may also influence individual susceptibility. However, the effects of major lifestyle and hereditary risk factors on the development of EC remain poorly understood in China. Moreover, little attention has been paid to the etiological heterogeneity between similar areas with great risk gradient. [Methods]From 2003 to 2007, a large population-based case-control study of EC has been conducted in a selected high-risk area and a selected low-risk area of Jiangsu Province, one of the highest cancer incidence areas in China. In total, 1,520 cases and 3,879 controls were recruited. In this thesis, we evaluated the role of major lifestyle factors such as tobacco smoking, alcohol drinking and dietary factors, as well as inherited determinants including family history of cancer and genetic polymorphisms of alcohol-metabolizing related genes on the risk of EC. In addition, we investigated how much of the risk gradient between two areas could be explained by variation in the distributions of major risk factors. [Results] Tobacco smoking and alcohol drinking moderately increased the risk of EC, while the positive associations were only found among men but not among women. Dietary factors were observed to play important roles in the development of EC. Specific dietary habits i.e., fast eating speed, and hot eating and/or drinking substantially elevated EC risk and could explain more than 20% of EC cases each. High intake of salty foods and fried foods, low consumption of raw garlic were also observed to increase the risk of EC. In addition to environmental and lifestyle factors, we confirmed that a positive family history can significantly increase EC risk, and found the inheritance may modify the effect of some unhealthy lifestyles. Moreover, we further explored the relationship between EC and single nucleotide polymorphismsof ADH1B, ADH1C and ALDH2 genes. Results showed that the slow metabolizing ADH1B G allele, ADH1C G allele and ALDH2 A allele significantly increased EC risk among moderate-to-heavy alcohol drinkers, and a significant interaction was observed between ALDH2 gene and alcohol consumption. Lastly, we found that more than 60% of EC cases could be attributable to major lifestyle risk factors in the study population; furthermore, dissimilar distribution of several lifestyle factors, together with variations of hereditary factors may be largely responsible for the incidence difference between two study areas. [Conclusion]The findings in this thesis confirm that unhealthy lifestyles including smoking, alcohol drinking and some dietary factors are the predominant risk factors of EC in China, and a large proportion of incidence difference between regions at varying risk could be attributed to the different prevalence of lifestyle factors. As most of the identified risk factors are modifiable, these could be translated into risk reduction prevention programs in China, and a substantial proportion of new EC cases are expected to be prevented by eliminating or avoiding these risk factors in the population. </p
Zhong xin liang zi bi te dui huan jing zhong wu li liang de tan ce
Chen, Dongqing = 中心量子比特對環境中物理量的探測 / 陳冬青.Thesis Ph.D. Chinese University of Hong Kong 2015.Includes bibliographical references (leaves 100-103).Abstracts also in Chinese.Title from PDF title page (viewed on 28, October, 2016).Chen, Dongqing = Zhong xin liang zi bi te dui huan jing zhong wu li liang de tan ce / Chen Dongqing
Zhong-Yong as dynamic balancing between Yin-Yang opposites
PurposeThe purpose of this paper is to comment on Peter Ping Li’s understanding of Zhong-Yong balancing, presented in his article titled “Global implications of the indigenous epistemological system from the East: How to apply Yin-Yang balancing to paradox management.” Seeing his understanding of Zhong-Yong balancing being incorrect and incomplete, the author proposes an alternative perspective on Zhong-Yong as dynamic balancing between Yin-Yang opposites.Design/methodology/approachThe author first explain why Peter P. Li’s “asymmetry” and “superiority” arguments are flawed by referring to the original text of the classical book of Zhong-Yong (中庸) and a comparison between Zhong-Yong and Aristotle’s doctrine of the mean. The author then propose an alternative approach to Zhong-Yong balancing that is embedded in the original text Zhong-Yong but somehow has been neglected by many Chinese scholars. The author concludes the commentary by unifying the two alternative approaches to Zhong-Yong balancing under the inclusion-selection-promotion-transition (ISPT) framework of Zhong-Yong balancing.FindingsThere are three main findings. First, as the original text of Zhong-Yong does not prescribe asymmetry, Peter P. Li’s notion of “Yin-Yang balancing” is ironically unbalanced or anti-Zhong-Yong due to his emphasis on asymmetry to the exclusion of symmetry. Second, due to the equivalency between Zhong-Yong and Aristotle’s doctrine of the mean, Peter P. Li’s assertion that “Yin-Yang balancing” is superior as a solution to paradox management is flawed. Third, his “Yin-Yang balancing” solution is only (the less sophisticated) one of two alternative approaches to Zhong-Yong balancing, i.e., ratio-based combination of Yin-Yang opposites. What Peter P. Li and many other Chinese have neglected is another approach to Zhong-Yong that is embedded in the original text of Zhong-Yong, which I call “analysis plus synthesis.”Research limitations/implicationsAs it is a commentary there are no specific limitations except for what can be covered in the space available.Practical implicationsThe “analysis plus synthesis” approach to Zhong-Yong can be adopted by practitioners who are demanded to balance between opposite forces in daily life and work.Social implicationsThe rejection of the “Yin-Yang balancing being superior” assertion facilitates reduction of friction and non-cooperation between intellectual traditions.Originality/valueThis commentary contributes to the “West meets East” discourse by debunking Peter P. Li’s assertion that Yin-Yang balancing is superior as a solution to paradox management and his prescription that balancing between Yin-Yang opposites must be asymmetric. It also contributes to the Chinese indigenous management research by identifying a largely neglected approach to Zhong-Yong balancing (i.e. “analysis plus synthesis”) that is alternative to the commonly understood ratio-based combination approach (e.g. “Yin-Yang balancing”). In addition, it contributes to the management literature by proposing the ISPT framework of Zhong-Yong balancing
Zhong-Yong as dynamic balancing between Yin-Yang opposites
Purpose
The purpose of this paper is to comment on Peter Ping Li’s understanding of Zhong-Yong balancing, presented in his article titled “Global implications of the indigenous epistemological system from the East: How to apply Yin-Yang balancing to paradox management.” Seeing his understanding of Zhong-Yong balancing being incorrect and incomplete, the author proposes an alternative perspective on Zhong-Yong as dynamic balancing between Yin-Yang opposites.
Design/methodology/approach
The author first explain why Peter P. Li’s “asymmetry” and “superiority” arguments are flawed by referring to the original text of the classical book of Zhong-Yong (中庸) and a comparison between Zhong-Yong and Aristotle’s doctrine of the mean. The author then propose an alternative approach to Zhong-Yong balancing that is embedded in the original text Zhong-Yong but somehow has been neglected by many Chinese scholars. The author concludes the commentary by unifying the two alternative approaches to Zhong-Yong balancing under the inclusion-selection-promotion-transition (ISPT) framework of Zhong-Yong balancing.
Findings
There are three main findings. First, as the original text of Zhong-Yong does not prescribe asymmetry, Peter P. Li’s notion of “Yin-Yang balancing” is ironically unbalanced or anti-Zhong-Yong due to his emphasis on asymmetry to the exclusion of symmetry. Second, due to the equivalency between Zhong-Yong and Aristotle’s doctrine of the mean, Peter P. Li’s assertion that “Yin-Yang balancing” is superior as a solution to paradox management is flawed. Third, his “Yin-Yang balancing” solution is only (the less sophisticated) one of two alternative approaches to Zhong-Yong balancing, i.e., ratio-based combination of Yin-Yang opposites. What Peter P. Li and many other Chinese have neglected is another approach to Zhong-Yong that is embedded in the original text of Zhong-Yong, which I call “analysis plus synthesis.”
Research limitations/implications
As it is a commentary there are no specific limitations except for what can be covered in the space available.
Practical implications
The “analysis plus synthesis” approach to Zhong-Yong can be adopted by practitioners who are demanded to balance between opposite forces in daily life and work.
Social implications
The rejection of the “Yin-Yang balancing being superior” assertion facilitates reduction of friction and non-cooperation between intellectual traditions.
Originality/value
This commentary contributes to the “West meets East” discourse by debunking Peter P. Li’s assertion that Yin-Yang balancing is superior as a solution to paradox management and his prescription that balancing between Yin-Yang opposites must be asymmetric. It also contributes to the Chinese indigenous management research by identifying a largely neglected approach to Zhong-Yong balancing (i.e. “analysis plus synthesis”) that is alternative to the commonly understood ratio-based combination approach (e.g. “Yin-Yang balancing”). In addition, it contributes to the management literature by proposing the ISPT framework of Zhong-Yong balancing.
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A Fast and Accurate Process Variation-aware Modeling Technique for Resistive Bridge Defects
Recent research has shown that tests generated without taking process variation into account may lead to loss of test quality. At present there is no efficient device-level modeling technique that models the effect of process variation on resistive bridge defects. This paper presents a fast and accurate technique to achieve this, including modeling the effect of voltage and temperature variation using BSIM4 transistor model. To speedup the computation time and without compromising simulation accuracy (achieved through BSIM4) two efficient voltage approximation algorithms are proposed for calculating logic threshold of driven gates and voltages on bridged lines of a fault-site to calculate bridge critical resistance. Experiments are conducted on a 65-nm gate library (for illustration purposes), and results show that on average the proposed modeling technique is more than 53 times faster and in the worst case, error in bridge critical resistance is 2.64% when compared with HSPICE
Li yong zhong zi bei qing bu huo de xun hao zai Daya Wan he dian chang ce liang zhong wei zi de zhen dang jiao θ₁₃
Xu, Jianyi = 利用中子被氫捕獲的訊號在大亞灣核電廠測量中微子的振蕩角θ₁₃ / 徐建一.Thesis Ph.D. Chinese University of Hong Kong 2015.Includes bibliographical references (leaves 177-182).Abstracts also in Chinese.Title from PDF title page (viewed on 15, November, 2016).Xu, Jianyi = Li yong zhong zi bei qing bu huo de xun hao zai Daya Wan he dian chang ce liang zhong wei zi de zhen dang jiao θ₁₃ / Xu Jianyi
Bluetooth Low Energy Application in home automation
Nowadays, the electrical devices for home automation are required to be multifunctional, with high design, and user-friendly. To meet the requirement of simple appearance and various functions, many manufactures create end to end(E2E) solutions e.g. for controlling an air purifier on a mobile device as was done for the commissioner here, remote control of devices with less or even no physical switches.
This trend has excited the release of many communications technologies of Machine to Machine(M2M), like Bluetooth, Zigbee, Zigwave, Enocean.
The author was commissioned by a Finnish air purification company, to develop a local wireless control of a stand-alone purifier device. This device would support cloud message control from the commissioner as application end (later referred to as App). Considering the geographic distance for maintenance, initial Bluetooth setup would help to provide the user access to further manual control or a WIFI configuration.
The thesis project focused on building a Bluetooth communication application on responder side, the purifier itself, to exchange data with the initiator device, the commissioners mobile end, which has App for this. The target here was to present a prototype with full functions, a stable connection and discuss about the further implementation on security pairing
[[alternative]]Recognition of printed sheet music using hough trasform and morphology operations
資訊教育學系
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