290 research outputs found
A bookworm who hatched
No full textNoted children's author and storyteller Verna Aardema recounts her life and describes how her daily activities and writing process are interwoven. In this autobiographical account, the noted author reveals stories about her life, writing techniques, and how she interacts with her reading audienceElementary Grad
Class of 1926
No full textThe Class of 1926, first class to graduate from North Carolina Baptist Hospital School of Nursing. Graduates front row L-R: Verna Aldridge, Gertrude Rogers, Miss Edna Heinzerling, director of school; Mildred Wall, Mary Poplin. Back row L-R: Elizabeth Griffith, Marion Parks, Susie Beach, Clarice Tuttle, Bryte Wilson and Lennie Ward.Published in Baptist Hospital News, 1948
Induction of Antihuman C–C Chemokine Receptor Type 5 Antibodies by a Bovine Herpesvirus Type-4 Based Vector
Get PDFBovine herpesvirus 4 (BoHV-4) is a promising vector for the delivery and intracellular expression of recombinant antigens and can thus be considered as a new prototype vaccine formulation system. An interesting, and actively pursued, antigen in the context of human immunodeficiency virus (HIV) infection prophylaxis (and therapy) is the C–C chemokine receptor type 5 (CCR5) co-receptor, whose blockage by specific antibodies has been shown to inhibit both viral entry and cell-to-cell transmission of the virus. Building on our previous work on the BoHV-4 vector system, we have engineered and tested a replication-competent derivative of BoHV-4 (BoHV-4-CMV-hCCR5ΔTK) bearing a human CCR5 (hCCR5) expression cassette. We show here that CCR5 is indeed expressed at high levels in multiple types of BoHV-4-CMV-hCCR5ΔTK-infected cells. More importantly, two intravenous inoculations of CCR5-expressing BoHV-4 virions into rabbits led to the production of anti-CCR5 antibodies capable of reacting with the CCR5 receptor exposed on the surface of HEK293T cells through specific recognition of the amino-terminal region (aa 14–34) of the protein. Given the growing interest for anti-CCR5 immunization as an HIV control strategy and the many advantages of virus-based immunogen formulations (especially for poorly immunogenic or self-antigens), the results reported in this study provide preliminary validation of BoHV-4 as a safe viral vector suitable for CCR5 vaccination
The dynamic landscape of liver transplant in the era of effective hepatitis C virus therapy
No full textHepatitis C viremic donors for hepatitis C nonviremic liver transplant recipients: Ready for prime time?
No full textThe Pine Branch, February 1922
No full textThe Pine Branch. Periodical magazine. Created and published by the Writers Club of the Georgia State Womans College, Valdosta, Georgia. Includes: editorials, photographs, poems, short stories, and other writings.On the Ninth Anniversary of S. G. S. N. C P Mary Ethel Moses; Frances Dekle; Estelle Barker; Mary Poindexter; Verna Scarborougs; Edna Roberson; Sally Kate Wolfe; Birdie VanBrackle; Leo Prine; Eppie Robertson; Madeline Culbreth; Page 1 | Valentine and a Haircut Page 2 | Three Maids and a Male Person Page 6 | Thrills Subdued Page 9 | Bidding the Home Boys Farewell Page 10 | Editorial Page 12 | Twigs Page 14 | Locals Page 15 | Alumnae Page 17 | Society Notes Page 18 | Humorous Page 20
Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease
No full textObjective: Wheat gluten and related proteins can trigger an autoimmune enteropathy, known as coeliac disease, in people with genetic susceptibility. However, some individuals experience a range of symptoms in response to wheat ingestion, without the characteristic serological or histological evidence of coeliac disease. The aetiology and mechanism of these symptoms are unknown, and no biomarkers have been identified. We aimed to determine if sensitivity to wheat in the absence of coeliac disease is associated with systemic immune activation that may be linked to an enteropathy. Design: Study participants included individuals who reported symptoms in response to wheat intake and in whom coeliac disease and wheat allergy were ruled out, patients with coeliac disease and healthy controls. Sera were analysed for markers of intestinal cell damage and systemic immune response to microbial components. Results: Individuals with wheat sensitivity had significantly increased serum levels of soluble CD14 and lipopolysaccharide (LPS)-binding protein, as well as antibody reactivity to bacterial LPS and flagellin. Circulating levels of fatty acid-binding protein 2 (FABP2), a marker of intestinal epithelial cell damage, were significantly elevated in the affected individuals and correlated with the immune responses to microbial products. There was a significant change towards normalisation of the levels of FABP2 and immune activation markers in a subgroup of individuals with wheat sensitivity who observed a diet excluding wheat and related cereals. Conclusions: These findings reveal a state of systemic immune activation in conjunction with a compromised intestinal epithelium affecting a subset of individuals who experience sensitivity to wheat in the absence of coeliac disease
W. C. Stripling Junior High School dance chorus
No full textA student dance chorus will kick and twirl in the Stripling Revue in the W. C. Stripling Junior High School Auditorium. The girls are posed in a chorus line kick. They are left to right, Elizabeth Little, Verna Jean Holmes, Beverly Grafa, Elaine Richardson, Peggy Lewis, Patsy Boggerman, Barbara Barse, Yvonne Huffman, Jane Spears, Patsy Durham, Lola Thompson, Katie Sanders, Ruth Seele, Emma Jean Lamar, Beverly Yager and Mary Jo Halsell. The show is composed of eighteen numbers of singing, dancing, rope jumping, and folk dancing under the direction of R. C. Conlee and Jessie Belle Palmer, physical education instructors. Proceeds will be used by the Parent-Teacher Association to assist students with financial difficulties. Published in the Fort Worth Star-Telegram evening edition, April 25, 1941.https://mavmatrix.uta.edu/specialcollections_startelegram1940s/7914/thumbnail.jp
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