92 research outputs found

    Vignale (Piombino). Le terme di una villa/mansio nel tempo, tra antichità e alto medioevo (?)

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    La ricerca archeologica in corso dal 2004 sul sito di Vignale, presso Piombino, ha riportato alla luce i resti di un complesso edilizio molto esteso e articolato, interpretato come villa/mansio, con fasi di vita che si distribuiscono tra l’epoca etrusca e l’età tardoantica/altomedievale. In questo contesto sono in corso di scavo almeno tre edifici termali, di diversa epoca e, al momento, a diverso grado di comprensione archeologica, posti in relazione spaziale e funzionale con il nucleo principale. Nello specifico, si tratta di: un piccolo impianto a due soli ambienti, presumibilmente costruito tra la tarda età repubblicana e l’età augustea; un edificio più grande e strutturato, non ancora completamente indagato, presumibilmente databile ad età imperiale; un impianto di dimensioni ancora più grandi, anch’esso in corso di scavo, databile ad età tardoantica, ma con evidenti tracce di continuità d’uso che potrebbero spingersi fino all’alto medioevo. Al di là dei loro diversi caratteri tipologici, costruttivi e funzionali, le tre (o forse quattro) terme riportate alla luce a Vignale aprono una interessante prospettiva di riflessione sulla trasformazione delle funzioni nel tempo all’interno di un singolo sito

    Gendering the comic body: Physical humour in <i>Shirley</i>

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    The mock-battles and slap-stick scenes that arise at pivotal moments in Shirley encourage us to reexamine Brontë’s sense of humour, which is neither as grim, nor as naively crude as critics from George Henry Lewes to Virginia Woolf have deemed it. Drawing on Brontë’s engagement with the theatrical traditions of European Carnival and British pantomime, this chapter demonstrates how physical humour in Shirley satirises the gendered dictates of literary realism that Lewes had laid out for the author in public reviews and private correspondence. By rejecting the witty drawing-room comedy often associated with her predecessor Jane Austen, and adopting the brash language of the body common to both popular performance and the work of her male peers Charles Dickens and William Makepeace Thackeray, Brontë participates in important mid-nineteenth-century debates about gendered authorship and the literary marketplace.<br/

    Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells

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    In the peripheral nervous system, Schwann cells (SCs) demonstrate surveillance activity, detecting injury and undergoing trans-differentiation to support repair. SC receptors that detect peripheral nervous system injury remain incompletely understood. We used RT-PCR to profile ionotropic glutamate receptor expression in cultured SCs. We identified subunits required for assembly of N-methyl-d-aspartic acid (NMDA) receptors (NMDA-R), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, and kainate receptors. Treatment of SCs with 40-100 μM glutamate or with 0.5-1.0 μM NMDA robustly activated Akt and ERK1/2. The response was transient and bimodal; glutamate concentrations that exceeded 250 μM failed to activate cell signaling. Phosphoprotein profiling identified diverse phosphorylated proteins in glutamate-treated SCs in addition to ERK1/2 and Akt, including p70 S6-kinase, glycogen synthase kinase-3, ribosomal S6 kinase, c-Jun, and cAMP response element binding protein. Activation of SC signaling by glutamate was blocked by EGTA and dizocilpine and by silencing expression of the NMDA-R NR1 subunit. Phosphoinositide 3-kinase/PI3K functioned as an essential upstream activator of Akt and ERK1/2 in glutamate-treated SCs. When glutamate or NMDA was injected directly into crush-injured rat sciatic nerves, ERK1/2 phosphorylation was observed in myelinated and nonmyelinating SCs. Glutamate promoted SC migration by a pathway that required PI3K and ERK1/2. These results identified ionotropic glutamate receptors and NMDA-R, specifically, as potentially important cell signaling receptors in SCs.-Campana, W. M., Mantuano, E., Azmoon, P., Henry, K., Banki, M. A., Kim, J. H., Pizzo, D. P., Gonias, S. L. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells

    HYDROLOGICAL AND STABILITY MODELLING OF INITIAL LANDSLIDES TRIGGERING DEBRIS FLOWS IN ASH-FALL DEPOSITS COVERING HILLSLOPES SURROUNDING SOMMA-VESUVIUS (SOUTHERN ITALY).

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    Rainfall-induced debris flows involving ash-fall pyroclastic deposits covering steep mountain slopes that surround the Somma-Vesuvius volcano, are natural events representing the main cause of risk for urban settlements located at footslopes. The presented research was based on the review of the wide scientific literature and was aimed to the improvement of some crucial aspects regarding the initiation of debris flows by means of field and laboratory experimental methods and modelling applied in representative sample areas of the Sarno Mountain Range, where deadly flow-like landslides initiated on May 5th - 6th 1998. Detailed stratigraphic and topographic surveys carried out in three representative initiation areas led to recognise that, depending on the slope angle, ash-fall pyroclastic deposits are discontinuously distributed along slopes, showing a total thickness that varies from a maximum value recognisable in the slope angle range lower than 30° up to be negligible for slope angle values greater than 50°, thus being strongly related to bedrock morphology itself. This distribution influences stratigraphical setting of ash-fall pyroclastic mantle leading to a downward thinning up to pinch out of pyroclastic horizons. Three fundamental quantitative engineering geological models were identified, in which the most part of the initial landslides occurred in May 1998 can be classified: i) knickpoints, characterised by a downward progressive thinning of pyroclastic mantle; ii) rocky scarps, identified as causing an abrupt interruption of pyroclastic mantle; iii) road cuts in pyroclastic mantle, whereas they occur in a critical slope angle range. Coupled geotechnical and saturated/unsaturated hydraulic characterisations of pyroclastic soils, led to the hydro-mechanical modelling of slope stability in the initiation areas. Results demonstrated that initial instabilities of pyroclastic mantle can occur without a hydraulic contribution from the carbonate bedrock, therefore critical increase of pore pressure derives from the infiltration and throughflow processes. Finally, the hydro-mechanical modelling of slope stability permitted the deterministic definition of intensity/duration hydrological thresholds

    Datata ad annum: l’agorà di Iasos di Caria. Considerazioni sull’architettura marmorea

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    This paper aimes to analyze the architectural and symbolic apparatus of the agora of Iasos in Caria, as reorganized between 135 and 139, that means in the last years of the reign of Hadrian and in the first years of the reign of Antoninus Pius. The new architectural feature makes use of a refined decorative pattern and polychromy, deriving from various qualities of marble. The dedicatory inscriptions illuminate the evergetic activity of private citizens, the tribute to the emperor, the relationship with the tutelary deities of the polis. From an epigraphic and architectural analysis also emerges a symbolic program that manifests the prestige of the client, a political aim and the value of the new architectural complex in the context of the polis

    Mortars, plasters and pigments—research questions and sampling criteria

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    [EN] Within the Topical Collection, this paper represents an introductory contribution aimed at describing and discussing the research questions and the sampling criteria in the field of mortars, plasters and pigments studies. The paper is divided into three parts. In the first part, some terminological issues are clarified and the building archaeology is introduced as an indispensable method for sampling and interpreting archaeometric results. In the second part, the most common research questions are presented and discussed. Some case studies are also reported to clarify what the expected results may be. The sampling problem is faced in the third part, where the criteria for a representative, functional and suitable selection are provided.Peer reviewe
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