1,720,958 research outputs found
Comparison of Intra-articular Injection of PRGF and Corticosteroid When Used as an Adjunct to Temporomandibular Joint Arthrocentesis: A Blinded Randomized Control Trial
Get PDFBackground: Intraarticular pain in dysfunction (IPD) is a notably prevalent condition affecting the temporomandibular joint. Both marcotrauma and microtrauma, from bruxism and parafunctional habits, can lead to internal derangement of the temporomandibular joint disc causing chronic inflammation and pain. Arthrocentesis is a surgical procedure used to reduce this inflammation and return the patient to painless function. Several drugs have been used as an adjunct to arthrocentesis. Research has suggested platelet concentrates may serve as a superior alternative supplement when used in combination with arthrocentesis from the treatment of IPD.
Objectives: To compare the clinical outcomes of platelet-rich in growth factor (PRGF) versus corticosteroid (CS) injections as adjuncts to temporomandibular joint (TMJ) arthrocentesis in patients with predominantly Wilkes stage II–III internal derangement.
Materials and Methods: This single-blinded randomized controlled trial included sixteen participants who underwent standardized unilateral TMJ arthrocentesis. Subjects were randomized to receive either intra-articular triamcinolone (40 mg) or PRGF (2 mL). Clinical outcomes—including maximum interincisal opening (MIO), average daily pain, maximum pain intensity, joint sounds, and muscle tenderness—were recorded preoperatively and at 7, 30, 90, and 180 days postoperatively.
Results: At 6 months, the CS group demonstrated a greater mean improvement in MIO (+7.0 mm) compared with PRGF (–8.6 mm). PRGF resulted in a significant reduction in average daily pain in the early follow-up period, however steroid provided similar early pain reduction, and improved long term pain reduction. Joint sounds and muscle tenderness declined slightly in both groups, with no significant differences between treatments.
Conclusion: Given the small sample size, higher attrition in the PRGF group, and lack of quality-of-life measures, findings should be interpreted with caution. Within these limitations, PRGF did not demonstrate superiority over corticosteroids as an adjunct to TMJ arthrocentesis.Foundation for Continuing Education and Research (CAOMS) Research Gran
A prospective evaluation of peri-operative glucocorticoid use in the management of cervicofacial infections of odontogenic origin
No full textOdontogenic cervicofacial infections requiring inpatient management are treated in a routine manner by oral and maxillofacial surgeons in Manitoba. After a standardized pre-operative workup, patients undergo surgical intervention including extraction of necessary teeth and incision and drainage of associated abscess(es). Patients are treated post-operatively with antibiotics, steroids, and medications for supportive care until appropriate for discharge.
Benefits of intravenous corticosteroids in patients undergoing dentoalveolar and maxillofacial surgery include improved comfort, reduced post-operative edema, and shortened time to recovery. Corticosteroids also aid in reducing the risk of morbidity by limiting mass effect from edema and associated airway obstruction. In addition, their anti-inflammatory effect limits further swelling from manipulation of soft tissues during surgical procedures. Current literature supports the use of corticosteroids in the management of primary and deep space neck infections. However, corticosteroid dosing regimens are currently determined by the clinical judgment of the attending surgeon and are not standardized.
The purpose of this study was to provide guidance for optimal dosing of methylprednisolone in the management of odontogenic cervicofacial infections. This prospective study followed the inpatient course of 28 patients with various cervicofacial infections of odontogenic origin. All patients were treated with a standardized surgical protocol, antibiotics, and steroids. Patients were randomized to receive one of two methylprednisolone dosing regimens. 14 patients were assigned to receive one dose of methylprednisolone 125mg IV at the time of surgery. The remaining 14 patients received one dose of methylprednisolone 125mg IV at the time of surgery and three consecutive doses of methylprednisolone 125mg IV every six hours post-operatively. Patients were evaluated at the time of hospital presentation and daily throughout admission. Outcomes evaluated included C-reactive protein (CRP) levels, white blood cell (WBC) count, length of hospital admission, and trismus. By examining differences in outcome success variables, the goal of this study was to support future evidence-based dosing decisions in the peri-operative treatment of inpatients in Manitoba. Data analysis showed a greater reduction in CRP throughout admission in the four-dose methylprednisolone group that was statistically significant. No significant difference in daily WBC count or trismus was found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
An Evaluation of Handheld Ultrasonography in Comparison to MRI for the Diagnosis of Temporomandibular Joint Disorders
Get PDFMRI is the gold standard of imaging modalities for the diagnoses of internal derangement (ID) of the Temporomandibular Joint (TMJ). MRI scans are non-invasive, use non-ionizing radiation, and provide valuable information on the position and morphology of joints, tissues and bony structures. MRI has disadvantages and patients with severe TMJ pain may find it difficult to complete a full TMJ scan series. The heavy demand for MRI utilization and resulting wait times prolong the interval between initial consultation and diagnosis. MRI is also expensive, inconvenient, and contraindicated in patients with certain metallic implants (Orhan & Aksoy, 2019). For these reasons, the author believes that finding an alternative diagnostic device for ID that is convenient and reliable is of critical importance.
There is a limited body of encouraging evidence demonstrating that mobile ultrasound sonography (mUS), can act as a diagnostic adjunct to MRI for assessment of Temporomandibular Joint Disorders (TMD’s), including ID and Degenerative Joint Disease (DJD). The use of mUS has no known contraindications, is readily accessible, comparatively inexpensive, and requires no special preparation (Orhan & Aksoy, 2019).
The purpose of this paper is to summarize the findings of original research into the Accuracy of handheld ultrasound sonography (HHU), in comparison to MRI, for the diagnoses of patients with TMD. The scans focussed on Anterior Disk Displacement (ADD) without reduction (ADDwoR), ADD with reduction (ADDwR) and arthritic changes (OA). Using a 95% CI and 5% p-value, when diagnosing ADDwoR, HHU was found to have a Sensitivity of 96.77%, Specificity of 100%, PPV of 100%, and NPV of 90%. When diagnosing ADDwR, Sensitivity was 76.50%, Specificity 100%, PPV 100%, and NPV 85.20%. The perfect Specificity means HHU is good at identifying patients that have a normal disc-condyle relationship and do not have ADD, while the perfect PPV means a high likelihood the tested patient has ADD.
Results indicate that HHU is a highly Specific test, with no false negatives, and an acceptable Sensitive test, with few false positives. HHU, in conjunction with questionnaires and clinical examination, shows promise as a first line imaging modality and screen for MRI referral
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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