1,070 research outputs found

    Supplemental Material - Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed consciousness

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    Supplemental Material for Development and validation of a novel poisoning agitation-sedation score for predicting the need for endotracheal intubation and mechanical ventilation in acutely poisoned patients with disturbed consciousness by Soha A. Abd Elghany, Heba I. Lashin, Ghada N. El-Sarnagawy, Merfat M. Oreby, and Eman Soliman in Human & Experimental Toxicology.</p

    Simple method for synthesis of isolated heterocyclic compounds incorporating 2-(2-bromoacetyl)isoindoline-1,3-dione and 2-(2-cyanoacetyl)isoindoline-1,3-dione

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    1194-12042-(2-Bromoacetyl)isoindoline-1,3-dione 2 and 2-(2-cyanoacetyl)isoindoline-1,3-dione 3 have been used as starting intermediates for synthesis of functionalized heterocyclic derivatives such as, 2-(2-aminothiazol-5-yl)isoindoline-1,3-dione 4, 2-(2-(benzylideneamino)thiazol-5-yl)isoindoline-1,3-dione 5, 2-(2-(3-chloro-2-oxo-4-phenylazetidin-1-yl)thiazol-5-yl)isoindoline-1,3-dione 6, 2-(2-(4-oxo-2-phenylthiazolidin-3-yl)thiazol-5-yl)isoindoline-1,3-dione 7, 2-(2-arylhydrazono)-2-bromo(cyano)acetyl)-isoindoline-1,3-dione 8, 6-bromo-5-(1,3-dioxoisoindolin-2-yl)-3-oxo-2-phenyl-2,3-dihydropyridazine- 4-carbonitrile 10a, 4-(1,3-dioxoisoindolin-2-yl)-6-oxo-1-phenyl-1,6-dihydropyridazine-3,5-dicarbonitrile 10b, 1-acetyl-3-(1,3-dioxoisoindolin-2-yl)-5-aryl-4,5-dihydro-1H-pyrazole-4-carbonitrile 12, 4-cyano-3-(1,3-dioxoisoindolin-2-yl)-5-aryl-4,5-dihydro-1H-pyrazole-1-carbothioamide 13, 3-(1,3-dioxoisoindolin-2-yl)-1-(4-oxo-4,5-dihydrothiazol-2-yl)-5-phenyl-4,5-dihydro-1H-pyrazole-4-carbonitrile 14, 3-(1,3-dioxoisoindolin-2-yl)-1-(5-(1,3-dioxoisoindolin-2-yl)thiazol-2-yl)-5-phenyl-4,5-dihydro-1H-pyrazole-4-carbonitrile 15, 2-(3-amino-5-(phenylamino)-1H-pyrazole-4-carbonyl)isoindoline-1,3-dione 17, 2-(5,7-dimethyl-2-(phenyl-amino)pyrazolo[1,5-a]pyrimidine-3-carbonyl)isoindoline-1,3-dione 18 and 2-(7-phenyl-2-(phenyl-amino)pyrazolo[1,5-a]pyrimidine-3-carbonyl)isoindoline-1,3-dione 20. The synthesized compounds have been characterized by IR, MS, 1H NMR and 13C NMR spectral analy­sis. </span

    Reactivity of β-enamino ester of benzo[f]chromene: One pot synthesis of isolated and heterocycle-fused derivatives of benzo[f] chromene

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    The formation of isolated and fused benzo[f]chromene derivatives was achieved via reacting ethyl 3-amino-1-phenyl-1H-benzo[f]chromene-2-carboxylate (1) with some selected reagents under basic conditions. The new compound, ethyl 3-(dimethylaminomethyleneamino)-1-phenyl-1H-benzo[f]chromene-2-carboxylate  (2) was prepared from compound 1 and N,N-dimethyl formamide in presence of phosphorus oxychloride under mild conditions in excellent yield using Vilsmeier reaction. Also, 10-amino-12-phenyl-9-sulfanyl-12H-benzo[f] chromeno[2,3-d]pyrimidine-11(10H)-one (12), 10-aryl-14-phenyl-14H-benzo[f]chromeno [2,3-d][1,3,4]thiadiazolo[3,2-a]pyrimidine-13-one (15), ethyl 3-(4-oxo-2-thioxothiazolidin-3-yl)-1-phenyl-1H-benzo[f]chromene-2-carboxylate (18), ethyl 3-(4-phenyl-2-thioxothiazol-3(2H)-yl)-1-phenyl-1H-benzo[f]chromene-2-carboxylate (20), ethyl 3-acetamido-1-phenyl-1H-benzo[f]chromene-2-carboxylate (21), and 10-amino-9-methyl-12-phenyl-12H-benzo[f] chromeno[2,3-d]pyrimidine-11(10H)-one (23) were prepared. The structures of these compounds were established by elemental analysis, IR, MS and NMR spectral analy­sis

    Precision agriculture technologies for food security and sustainability Advances in environmental engineering and green technologies (AEEGT) book series./ [edited by] Sherine M. Abd El-Kader, Basma M. Mohammad El-Basioni.

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    "Premier Reference Source"--Cover.Includes bibliographical references and index."Precision agriculture integrates new technologies with the agronomic experience to intelligently manage the high spatial variability of all agricultural variables and the time scales at which these variables change. The right application of this approach increases the size and quality of the agricultural production; saves resources; improves environmental quality; helps to achieve self-sufficiency, food security, and agricultural sustainability; increases exports; and more. Precision Agriculture Technologies for Food Security and Sustainability is an essential reference source that compiles a comprehensive, multidisciplinary review of current research in the field of precision agriculture. It also discusses cutting-edge tools and models that can help facilitate and improve the systems implementation. Featuring coverage of a wide range of topics including agronomy, public policy, and internet of things, this book is ideally designed for agriculturalists, government officials, economists, environmentalists, academicians, researchers, students, and engineers in the fields of electronics, ICT, and agriculture"--Introduction. Introduction to precision agriculture : overview, concepts, world interest, policy, and economics / Akalpita Tendulkar -- Precision agriculture : a new tool for development / Waleed Fouad Abobatta -- Enabling technologies. An overview of internet of things technology applied on precision agriculture concept / Reinaldo Padilha França [and three others] -- Towards fully automated decision-making systems for precision agriculture : soil sensing technologies : "the missing link" / Marios Sophocleous -- Emerging microwave technologies for agricultural and food processing / Kok Yeow You, Man Seng Sim, Suhail Najm Abdullah -- Applications and solutions. Precision agriculture : automated irrigation management platform using wireless sensor networks / Amine Dahane [and three others] -- On the use of artificial intelligence techniques in crop monitoring and disease identification / Muzaffer Kanaan, Rüştü Akay, Canset Koçer Baykara -- Precision management practices for legal cultivation of cannabis (Cannabis sativa L.) : precision management practices for cannabis cultivation / Aitazaz Ahsan Farooque, Farhat Abbas -- Predictable scenarios of fuzzy logic analysis for sprinkler irrigation control / Mohamed Elsayed Elhagarey, Mohamed M. Hushki, Szabo E. Istvan -- A web-based platform for crop-specific data management and exchange of farmers' experiences / Rosa Maria Gonzalez-Amaro, Miguel Angel Hidalgo-Reyes, Virginia Lagunes-Barradas -- Raising the efficiency of Seohen's model to predict soil resistance faced by chisel plow / Adil Abd Elsamia Meselhy -- Agricultural systems analysis streamlining, modeling, and improvements : towards precision agronomics (economic and policy perspective). The role of the institutional, assistance, and source information analysis on food security and extension policy : case in Indonesia / Muhamad Rusliyadi -- Agricultural systems analysis streamlining, modeling, and improvements : towards precision agronomics (technological perspective). Importance of artificial environment conditions on plant biotechnology, plant growth, and secondary metabolites / Ahmed M.M. Gabr [and three others] -- Role of biotechnology in plant preservation for food security : in situ and ex situ preservation / Amal A. El-Ashry, Ahmed M.M. Gabr, Mohamed K. El Bahr -- Lipids in ruminant nutrition and its effect on human health / Eman H. Elsabaawy, Sawsan M. Gad.1 online resource (xix, 437 pages)

    Impact of coronavirus pandemic on cancer patients; is it time for ectoine and/or ACE inhibitors?

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    Cancer patients require attention after COVID-19. ACEI and/or ectoine could represent potential adjuvant therapy. Clinical trials are required to investigate this hope to mitigate COVID-19 infectivity and cell invasion.</p

    Exploring factors affecting Employee Loyalty through the relationship between Service Quality and Management Commitment a case study analysis in the iron and steel industry Al Ezz Dekheila Steel Company in Egypt

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    The purpose of this study is to discover factors affecting employee loyalty through the relationship between service quality and management commitment from the employees’ perspective on the iron and steel industry, specifically in Al Ezz Dekheila Steel Company (EZDK) (a Middle East steel producer with a global reach) in Egypt. The author employed an inductive qualitative research approach through semi-structured interviews with 15 employees from different managerial levels (top, middle, and divisional) to achieve the study aim. All interviews were conducted in Arabic, the mother tongue of all respondents. Data were gathered personally by the researcher and statistically analyzed using thematic analysis to determine the main ideas of the transcripts. Based on the analysis of the interviews, the study has identified main themes, which refer to the important factors identified by employees of EZDK. Through these themes, the conceptual framework of factors affecting employee loyalty is developed. Five main themes are presented, where each theme consists of many codes. Themes and codes could be represented as follows; theme of Corporate Social Responsibility (Environmental Impact, Helping the Government, CSR Projects, and Reducing Energy Consumption), theme of Quality of Service Offered to Employees (Safety Climate, Service Recovery Performance, and Policies), theme of Working Atmosphere (Friendly, Supportive, Teamwork, Fair environment, and obstacles of CRM), theme of Management Commitment (Management support, Supervisor Support, and Transparency) and theme of Employee Loyalty (Employees Empowerment, Employees Satisfaction, Employees planning, and being a part of the company). This paper contributes by filling the gap in the business field in both marketing (service quality, internal marketing) and management (HR, CSR) in discovering the factors affecting employee loyalty from the employees’ frame of reference, as it is considered as the first of its sort to develop a conceptual framework that explores the factors affecting employee loyalty in the iron and steel industry in the setting of one of the leading developing nations in Africa and the Middle East

    Can Co-enzyme Q10 improve the chances of conception after the age of 35?

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    Background: ovarian follicular quality diminishes with age, Free radicals and oxidative stress begin to accumulate in cells, aging or slowing down the metabolic energy production centers in the cell- the mitochondria. When the mitochondria cannot generate a certain amount of energy, it slows growth and proper development of the follicle making it more prone to DNA damage, including chromosomal abnormalities resulting in poor fertilization patterns, and early miscarriage. Co-enzyme Q10 (CoQ10) is a major cellular antioxidant. its tissue levels gradually decrease with age. We attempt to evaluate its protective effect on ROS-induced ovarian damage, which is one of the most important and widely accepted patho- mechanisms underlying cell ageing.Methods: 40 Participants   from El Shatby hospital infertility clinic 35 to 38 years old, with history of bad response to ovulation stimulation, were divided into two equal groups (group A given (CoQ10) 3mg|kg body weight for three cycles prior to stimulation Serum anti- mullarian hormone level was measured before and after CoQ10 administration, group B= twenty cases as control). Participants were given gonadotrophins (150 IU to 375 IU). Follicular growth was monitored by trans- vaginal ultra- sonography and serum estradiol level (E2). Ovulation trigger was achieved using 10,000 IU of human chorionic gonadotrophin.Results: The primary outcome was occurrence of normal pregnancy; secondary outcome was good response to stimulation (at least one mature follicle 18-22mm).Conclusions: CoQ10 has no significant effect on response to ovulation stimulation or on pregnancy rates.</jats:p

    Uterine Cavity Abnormalities in Patients with Endometriosis in Alexandria: A Diagnostic Test Accuracy Study

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    Endometriosis is strongly associated with infertility. Endometrial polyps are prevalent in infertile women and they have similar pathological characteristics to endometriosis, suggesting a possible association. Uterine malformations as uterine septum and hypoplastic uterus are also linked to endometriosis. Hysterosalpingogram and transvaginal ultrasonography are used to diagnose endometrial lesions. Hysteroscopy can detect small lesions that might be missed. Recently, 4D ultrasonography is being used, but which is superior has not been established yet. We aim to compare 4D ultrasonography to office hysteroscopy in evaluating uterine cavity in cases with endometriosis; also we aim at correlating these findings with the stage of endometriosis. 50 cases of endometriosis diagnosed by laparoscopy were randomly selected from El Shatby fertility clinic, Alexandria University, Egypt, with exclusion of cases with any previous intrauterine surgery or any hormonal treatment. Transvaginal 4D ultrasonography and office hysteroscopy were done. 4D ultrasonography agreed with office hysteroscopy in diagnosing abnormal uterine findings in 14 cases and four additional cases were diagnosed by hysteroscopy alone. Conclusion. Endometrial polyps, septate uterus, and hypoplastic uterus are more prevalent among infertile women who happen to have endometriosis. 4D ultrasonography and office hysteroscopy are equally successful in assessing the uterine cavity
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