2,768 research outputs found
Noted Bioethicist Discusses Lifestyle Impact of Genetic Information in Lawrence University Address
No full textGlenn McGee, one of the country’s best known and most often-quoted bioethicists, examines the ways genetic information may soon be used in radically new ways at home, at work and at leisure in a Edward F. Mielke Lecture Series in Biomedical Ethics address at Lawrence University.
McGee, the associate director of the Center for Bioethics at the University of Pennsylvania, presents “The User’s Guide to Having a Genome: Why Genetics Will Change Who You Marry, What Kind of Life You Have, or How You Make Most of Your Decisions,” Wednesday, Jan 28 at 7 p.m. in the Wriston Art Center auditorium on the Lawrence campus.
The author of the 2003 book, “Beyond Genetics: Putting the Power of DNA to Work in Your Life,” McGee envisions a world in the not-too-distant future where individuals will be able to do genetic testing at home with a device no bigger than a palm pilot and genetic manipulation will permit the creation of custom wonder drugs, engineered foods and even designer babies.
McGee cautions, however, that many important questions — who will own the knowledge gained from our genes, who will help us interpret the information and, perhaps the most basic of all, are these new genetic advances even desirable — need to be addressed before that technology is unleashed.
A specialist in ethical, legal, economic and social issues in biotechnology and biomedical sciences, especially reproductive genetics, stem cells and genomics, McGee is also the author of the 1997 book, “The Perfect Baby: Parenthood in the New World of Cloning and Genetics,” which has become the country’s best-selling book on genetics on parenthood. He also edited the book, “The Human Cloning Debate,” which offers arguments for and against cloning from scientific, philosophical and religious perspectives.
McGee, who earned his Ph.D. in 1994 from Vanderbilt University, where he served as the coordinator of the program in ethics and genetics. He joined the Bioethics Center at the University of Pennsylvania in 1995
Do Antimicrobial Resistance Patterns Matter? An Algorithm for the Treatment of Patients With Impetigo
No full textBACKGROUND: Impetigo, a highly contagious bacterial skin infection commonly occurring in young children, but adults may also be affected. The superficial skin infection is mainly caused by Staphylococcus aureus (S. aureus) and less frequently by Streptococcus pyogenes (S. pyogenes). Antimicrobial resistance has become a worldwide concern and needs to be addressed when selecting treatment for impetigo patients. An evidence-based impetigo treatment algorithm was developed to address the treatment of impetigo for pediatric and adult populations.METHODS: An international panel of pediatric dermatologists, dermatologists, pediatricians, and pediatric infectious disease specialists employed a modified Delphi technique to develop the impetigo treatment algorithm. Treatment recommendations were evidence-based, taking into account antimicrobial stewardship and the increasing resistance to oral and topical antibiotics.RESULTS: The algorithm includes education and prevention of impetigo, diagnosis and classification, treatment measures, and follow-up and distinguishes between localized and widespread or epidemic outbreaks of impetigo. The panel adopted the definition of localized impetigo of fewer than ten lesions and smaller than 36 cm2 area affected in patients of two months and up with no compromised immune status. Resistance to oral and topical antibiotics prescribed for the treatment of impetigo such as mupirocin, retapamulin, fusidic acid, have been widely reported.CONCLUSIONS: When prescribing antibiotics, it is essential to know the local trends in antibiotic resistance. Ozenoxacin cream 1% is highly effective against S. pyogenes and S. aureus, including methycyllin-susceptible and resistant strains (MRSA), and may be a suitable option for localized impetigo.J Drugs Dermatol. 2021;20(2):134-142. doi:10.36849/JDD.2021.5475 THIS ARTICLE HAD BEEN MADE AVAILABLE FREE OF CHARGE. PLEASE SCROLL DOWN TO ACCESS THE FULL TEXT OF THIS ARTICLE WITHOUT LOGGING IN. NO PURCHASE NECESSARY. PLEASE CONTACT THE PUBLISHER WITH ANY QUESTIONS
Stanford Law Professor Discusses Commodifcation in Opening Address of Lawrence University Biomedical Ethics Lecture Series
No full textStanford University Law Professor Margaret Jane Radin examines the contradictory nature of commodification — the transformation of relationships formerly untainted by commerce into commercial relationships of buying and selling — in the opening address of Lawrence University’s four-part 2004-05 Edward F. Mielke Lecture Series in Biomedical Ethics.
Radin, the William Benjamin Scott and Luna M. Scott Professor of Law at Stanford, presents “Commodification: Promise or Threat,” Monday, Nov. 15 at 7 p.m. in Lawrence’s Wriston Art Center auditorium. The lecture is free and open to the public.
A specialist in the fields of intellectual property, contracts and e-commerce, Radin will examine the evolving ethical issues associated with commodification, ranging from the solicitation of young women’s eggs in exchange for large sums of money to the international trade of human kidneys to the commercialization of technological methods of creating babies, such as in vitro fertilization.
Radin also will address the ways commodification both raises objections — if everything that human beings value becomes reduced to a dollar value, do we remain human? – and produces opportunities — the promise of technological baby-making can enhance autonomy and “personhood” and make people free to have children.
A 1963 graduate of Stanford and a member of the faculty there since 1986, Radin is currently teaching as a visiting professor at the University of Michigan School of Law. She served as director of Stanford Law School’s Program in Law, Science and Technology from 2001-2004 and co-authored the first standard law-school textbook dealing with Internet commerce.
A nationally recognized scholar on aspects of property as a right and as an institution, Radin is the author of two books on the subject, “Contested Commodities” and “Reinterpreting Property.” Her current research interests focus on contract and commodification in the online environment.
Other speakers and topics scheduled for the Mielke Lecture Series in Biomedical Ethics include:
• Jan. 12 — Angela Fagerlin, research investigator, internal medicine and the Program for Improving Health Care Decisions, University of Michigan, “Pulling the Plug on Living Wills: How Living Wills Have Failed to Live up to their Mandate.”
• Feb. 23 — David Dranove, Walter McNerney Distinguished Professor of Health Industry Management, Northwestern University, “Putting a Price on Life.”
• May 11 — Allen Buchanan, Professor of Public Policy Studies and Philosophy, Terry Stanford Institute of Public Policy, Duke University, “What Was Really Wrong with Eugenics?
''Menger Hotel,'' San Antonio, Texas
No full textThis view of the famous Menger Hotel in San Antonio was taken by A. F. Dignowity, the son of author, daguerreotypist, and physician Anthony Michael Dignowity. Dignowity operated for a relatively short period of time, and his work is uncommon. Source: Lawrence T. Jones III.Attributed to: Dignowity, A. F. (Anthony Francis), 1844-1921. Verso: [handwritten in ink] ''Menger Hotel'' San Antonio Texas
Journalism Excellence, Philanthropic Generosity, Literary Scholarship and Human Rights Activism Recognized at Lawrence University’s 155th Commencement
No full textFor the 25th — and final — time, Lawrence University President Richard Warch will lead the procession of seniors and honored guests to the stage where he’ll award honorary doctorates, confer bachelor’s degrees and congratulate students for completing their undergraduate education Sunday, June 13 during the college’s 155th commencement. Graduation ceremonies begin at 10:30 a.m. on the Main Hall green.
Warch will retire as Lawrence’s second-longest serving president at the end of the month. He is currently the longest-standing president of any college or university in Wisconsin and believed to be one of only 20 current presidents in the country who have served their present institutions for 20 years or more.
An expected 303 seniors, Lawrence’s largest graduating class since 1977, will receive Bachelor of Arts and/or music degrees. In addition, Lawrence will award honorary doctorate degrees to John Carroll, editor of the Los Angeles Times, Jonathan Fanton, president of the John D. and Catherine T. MacArthur Foundation, Stanley Fish, dean of the College of Liberal Arts and Sciences at the University of Illinois-Chicago and Samantha Power, lecturer in public policy at the John F. Kennedy School of Government at Harvard University.
Also, Professor of Music Robert Levy, who is retiring after 25 years as director of bands at Lawrence, will receive professor emeritus status and awarded an honorary master of arts degree, ad eundem.
A baccalaureate service, featuring Daniel Taylor, Hiram A. Jones Professor of Classics delivering the address “Making Connections,” will be held Saturday, June 12 at 11 a.m. in the Lawrence Memorial Chapel.
All four honorary doctorate degree recipients, along with President Warch, Lawrence Board of Trustees Chair Jeffrey Riester and student representative Andrea Hendrickson, a senior from Tillamook, Ore., will address the graduates during commencement. Both the baccalaureate service and commencement ceremony are free and open to the public.
Carroll, whose distinguished journalism career spans more than 40 years and includes seven Pulitzer Prizes, will receive an honorary doctor of laws degree. Named editor of the Los Angeles Times in 2001, he helped the paper earn five Pulitzers earlier this year, the second most ever won by a newspaper in a single year. The New York Times was awarded seven Pulitzer’s in 2002 for its coverage of the Sept. 11 terrorist attacks.
After beginning his career as a reporter for the Providence Journal in Rhode Island, Carroll was drafted into the Army and served in Alaska, writing for the base’s newspaper. He joined the Baltimore Sun as a reporter in the late 1960s, covering the Vietnam War and the Nixon administration. He became the subject of a front-page story in The New York Times after having his press credentials suspended for writing a story detailing U.S. plans to abandon Khe Sanh. Without his knowledge, the Army had imposed an embargo on news coverage of Khe Sanh. Following protests from media colleagues and a Congressional investigation, the Army restored Carroll’s credentials.
He spent seven years as a city editor and metropolitan editor at the Philadelphia Inquirer before being named editor of the Lexington Herald-Leader in Kentucky. Carroll returned to the Baltimore Sun as its editor in 1991, guiding it to Pulitzer Prizes in 1997 and ‘98 before taking editorial leadership of the Los Angeles Times.
Fanton, who will receive a honorary doctor of laws degree, has served as president of the Chicago-based MacArthur Foundation since September 1, 1999. With assets of nearly 180 million in support of public education, community development, system reform in mental health and juvenile justice, human rights, biodiversity preservation, reproductive health and international peace and security. It also supports public radio and television and the making of independent documentaries as well as support for exceptionally creative individuals through its famed “genius grant” Fellows program.
Before joining the MacArthur Foundation, Fanton served as president of New York City’s New School University (formerly known as New School for Social Research) from 1982-99. As president, he led the integration and enhancement of the seven divisions of the university, the expansion of the Greenwich Village campus and development campaigns that increased the university’s endowment from 80 million.
During his presidency, the New School merged with the Mannes College of Music, established a drama school in partnership with the Actor’s Studio, merged with the World Policy Institute, added a jazz and contemporary music program, a teacher education program, a creative writing program and an architecture department at Parsons School of Design.
Fanton began his career teaching American history at his alma mater, Yale University, where he earned his bachelor’s degree and Ph.D. He served as a special assistant to Yale President Kingman Brewster from 1970-73 and as associate provost from 1976-78. He then moved to the University of Chicago, where he spent the next four years as vice president for planning and also taught American history.
A board member of Human Rights Watch, the largest U.S.-based human rights organization and the Chicago Historical Society, Fanton is the author of “The University and Civil Society, Volumes I and II” and co-edited the books “John Brown: Great Lives Observed” and “The Manhattan Project: A Documentary Introduction to the Atomic Age.”
Fish will receive a doctor of humane letters. Considered one of America’s most distinguished scholars of English literature, law and literary theory, particularly the subjectivity of textual interpretation, he has served as a dean and distinguished professor of English, criminal justice and political science at UIC since 1999.
During an academic career spanning more than 40 years, Fish has held numerous major positions, including the Kenan Professor of English at Johns Hopkins University (1974-85) and the Arts and Sciences Distinguished Professor of English and Law at Duke University (1985-98). A USA Today article described Fish as “an erudite scholar who capably makes difficult subjects understandable… a brilliant original critic of the culture at large.”
Fish as written nearly a dozen books, among them “John Skelton’s Poetry,” “Surprised by Sin: The Reader in Paradise Lost,” the second edition of which received the Hanford Book Award in 1998, “Self-Consuming Artifacts,” which was nominated for a the National Book Award in 1972 and “There’s No Such Thing as Free Speech, and It’s a Good Thing, Too,” which earned the 1994 PEN/Spielvogel-Diamonstein Award. In the past 30 years, more than 200 articles, books, dissertations and review articles have been devoted to his work.
Fish is a frequent guest on shows ranging from the “MacNeil/Lehrer Newshour” to CNN’s “Firing Line” to “Hardball with Chris Matthews.” In 2003, the Chicago Tribune named him its “Chicagoan of the Year” for culture.
A graduate of the University of Pennsylvania, Fish earned his Ph.D. from Yale University and began his teaching career in the English department at the University of California-Berkeley.
Power, a human-rights activist, lawyer, scholar and award-winning author, will receive an honorary doctor of humane letters degree. Hrecent book, “A Problem from Hell: America and the Age of Genocide,” which examines U.S. responses to genocide in the 20th century, was awarded the 2003 Pulitzer Prize for general non-fiction, the 2003 National Book Critics Circle Award for general non-fiction and the Council on Foreign Relations’ Arthur Ross Prize for the best book in U.S. foreign policy.
She also co-edited the 2000 book, “Realizing Human Rights: Moving from Inspiration to Impact,” a collection of essays by leading activists, policy makers and critics who reflect upon 50 years of attempts to improve respect for human rights.
In 1998, she founded Harvard’s Carr Center for Human Rights Policy, which trains future leaders for careers in public service with a focus on the most dangerous human rights challenges, including genocide, mass atrocity, state failure and the ethics and politics of military intervention. She served as the Carr Center’s executive director until 2002.
A native of Ireland who moved to the United States when she was nine, Power covered the war in the former Yugoslavia from 1993-96 as a reporter for U.S. News & World Report, the Boston Globe and the London-based news magazine The Economist. A graduate of Yale University and Harvard Law School, she is currently working on a book on the causes and consequences of historical amnesia in American foreign policy
What is a Life Worth? “Rational” Rationing of Health Care Examined in Lawrence University Biomedical Ethics Series Address
No full textThe notion of rationing health care may be a frightening concept, but is it necessarily wrong?
Northwestern University Professor David Dranove explores the question of what is a life worth and offers insights on why “rational” rationing of health care resources is becoming increasingly embraced in the third installment of a Lawrence University’s 2004-05 Edward F. Mielke Lecture Series in Biomedical Ethics.
Dranove, the Walter McNerney Distinguished Professor of Health Industry Management at Northwestern, presents “Putting a Price on Life” Wednesday, Feb. 23 at 7 p.m. in Lawrence’s Wriston Art Center auditorium. The lecture is free and open to the public.
Drawing on Oregon’s 12-year old Medicaid initiative in which more than 700 medical interventions have been ranked from most cost effective to least and the British National Health System’s National Institute for Clinical Excellence (NICE), which examines the cost-effectiveness of expensive treatments and recommends against paying for the least cost-ineffective technologies, Dranove will discuss the growing acceptance of rational rationing and outline the promises and pitfalls associated with a rationing approach to health care.
An essential element of rational rationing is attempting to quantify the seemingly unanswerable question: what is a life worth? When health care is rationed, a threshold for cost-effectiveness is established and coverage is denied for treatment that falls below that threshold. In England, NICE routinely denies coverage for interventions that cost more than $93,500 per year of life saved. Other systems use similar valuations.
Dranove argues that if the value of a life is based on the best available evidence, then the threshold used by NICE and others is much too low. Properly implemented, Dranove believes rational rationing could lead to more health spending, not less, but with the promise that the money is spent wisely on something of unsurpassed value.
A specialist in medical economics and cost-benefit analysis, Dranove joined the Northwestern University Kellogg Graduate School of Management in 1991 after spending eight years teaching at the University of Chicago Graduate School of Business. He is the author of three books, including 2000′s “The Economic Evolution of American Health Care” and is in the process of completing a fourth, “Pricing Your Life.” Dranove earned a Ph.D. in economics from Stanford University
Profile of clindamycin phosphate 1.2%/benzoyl peroxide 3.75% aqueous gel for the treatment of acne vulgaris
No full textTuyet A Nguyen,1,2 Lawrence F Eichenfield1,31Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, CA, 2Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 3Department of Dermatology, University of California, San Diego, La Jolla, CA, USA Abstract: Acne vulgaris is a common and chronic skin disease, and is a frequent source of morbidity for affected patients. Treatment of acne vulgaris is often difficult due to the multifactorial nature of this disease. Combination therapy, such as that containing clindamycin and benzoyl peroxide, has become the standard of care. Several fixed formulations of clindamycin 1% and benzoyl peroxide of varying concentrations are available and have been used with considerable success. The major limitation is irritation and dryness from higher concentrations of benzoyl peroxide, and a combination providing optimal efficacy and tolerability has yet to be determined. Recently, a clindamycin and benzoyl peroxide 3.75% fixed combination formulation was developed. Studies have suggested that this formulation may be a safe and effective treatment regimen for patients with acne vulgaris. Here, we provide a brief review of acne pathogenesis, benzoyl peroxide and clindamycin, and profile a new Clindamycin-BP 3.75% fixed combination gel for the treatment of moderate-to-severe acne vulgaris. Keywords: acne vulgaris, benzoyl peroxide, clindamyci
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
The Web of Community Trust - Amateur Fiction Online: A Case Study in Community Focused Design for the Semantic Web
No full textThis thesis describes a case study online community: online amateur authors. Taking this case study community as a base, this thesis considers how the concept of community is applied within the Semantic Web domain. Considering the community structures that can be demonstrated through the case study, this thesis makes the case for the recognition of a specific type of social network structure, one that fulfills the traditional definitions of ‘community’. We argue that this sub-type occupies an important position within social networks and our understanding of them due to the structures required for them to be so defined and that there are assumptions and inferences which can be made about nodes within this type of community group but not others. Having detailed our case study community and the type of network it represents, this thesis goes on to consider how the community could be supported beyond the mailing lists and journalling sites upon which it currently relies. Through our investigation of the community’s issues and requirements, we focus on identity and explore this concept within the context of community membership. Further we analyse the community practice of metadata annotation, in comparison to other metadata systems such as tagging, and as it related to the development of the community. We propose a number of ontological models which we argue could assist the community and, finally, consider ways in which these models could be made available to the community in keeping with current practice and level of technical knowledge as evidenced by the community
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