5,074 research outputs found
Colección: Perfil #3
No full textThis board-book version of LM turns out to be quite creative. Ratoncete comes from school every afternoon and goes through the forest looking for adventures. He apparently blasts a horn into the ear of the sleeping lion. Don Leon wants to spank him as a result, but Ratoncete offers an apology, not an offer of help. Later, he happens upon the lion in his trap of ropes. 8 pages, counting both covers. 6½" x 9".Language note: SpanishNo Autho
Tyrosine phosphorylation of myosin heavy chain during skeletal muscle differentiation: an integrated bioinformatics approach
No full textBackground: Previously it has been shown that insulin-mediated tyrosine phosphorylation of myosin heavy chain is concomitant with enhanced association of C-terminal SRC kinase during skeletal muscle differentiation. We sought to identify putative site(s) for this phosphorylation event.Results: A combined bioinformatics approach of motif prediction and evolutionary and structural analyses identified tyrosines163 and 1856 of the skeletal muscle heavy chain as the leading candidate for the sites of insulin-mediated tyrosine phosphorylation.Conclusion: Our work is suggestive that tyrosine phosphorylation of myosin heavy chain, whether in skeletal muscle or in platelets, is a significant event that may initiate cytoskeletal reorganization of muscle cells and platelets. Our studies provide a good starting point for further functional analysis of MHC phosphor-signalling events within different cells.<br/
Psychotherapy, Counseling, and Coaching: different alternatives for Promoting Psychological Well-being.
No full textThis chapter analyzes three dominant approaches to mental health interventions: psychotherapy, counseling, and coaching. Their commonalities, as well as their main differences, are emphasized by using a continuum model encompassing time perspective; recipients of these interventions (ranging from patients with severe psychopathology, to distressed individuals, to normal populations); and types of therapeutic strategies that are applied. Psychotherapy, counseling, and coaching are differentiated in some ways because the first mainly refers to a medical model, whereas counseling and coaching rely on communication strategies. However, in current practice the distinctions are not as clear. Furthermore, they all share common ingredients, such as the working alliance, positive expectations, and the promotion of well-being
Markets Equilibrium: The Is-Lm Model
No full text. The purpose of this study is to analyze how the concept of markets equilibrium: the IS-LM Model. This research uses library research method by using reference sources from books and journals according to the theme. The author uses a qualitative method which is explained graphically, namely the market balance of the IS-LM model where the focus is on money and goods markets associated with macroeconomics where researchers take the side of investors. The results of this study are that the balance in the economy is the point where the IS and LM curves intersect. This point provides an interest rate (r) and income level (Y) that satisfies the equilibrium conditions that occur in the goods market and money market. In other words, planned spending equals actual spending, and the demand for real money balances equals the supply. So that the IS-LM balance, it is stated that IS=LM
<Articles>A Dynamical IS-LM Model
No full text[抄録]IS-LM モデルは、ヒックスによるケインズ経済学の因果関係を重視しながら要約したモデルと解釈することができる。IS-LM モデルの安定性分析はすでに研究成果があるが、1S-LM モデルの動学化はほとんど研究成果がない。本稿は IS-LM モデルの動学化を試みる。まず投資関数に資本ストックを取り入れ、資本蓄積と経済の変動を考える。次にカルドアモデルを考慮し、投資の予想収益率表の変化を仮定し、経済に循環が発生することを考察する。
[Abstract]In this paper, The author tries to build a Dynamical IS-LM Model. The lnvestment depends on two factors, one is the rate of interest, and the other is the rate of prosperity yield of the investment. I will focus on the second factor. As was shown by Kaldor, the rate of prosperity yield has nonlinear fluctuations. By means of this character, This study proposes an IS-LM model that generates a cycle.departmental bulletin pape
Raninella trigeri A. Milne Edwards 1862
No full textRaninella trigeri A. Milne Edwards, 1862 Raninella trigeri A. Milne Edwards, 1862: 492. (Fig. 26A–E) Material examined. From the upper Cenomanian of Le Mans, Butte de Gazonfier, two specimens, carapace and chelipeds (MHN LM 2003-1-3787A and B; Guéranger Collection); designated lectotype by Breton & Collins (2007: 18), complete specimen preserving chelipeds, portions of thoracic sternum and pereiopods (MNHN B16565; Triger Collection); paralectotype (see Brocchi 1877: pl. 29, fig. 3), one of the two carapaces (see also under Raninella elongata) (MNHN R03934); carapace with thoracic sternum and chelipeds, labels reading ‘ Raninella trigeri ’ and ‘ Hemioon elongatum ’(see Waugh et al. 2009: 27, figs. 5.3, 5.4) (NHM In. 63689 (Taylor & Hammond Collection). Remarks. Raninella trigeri (see A. Milne Edwards 1862: 493; Brocchi 1877: 2), from the Cenomanian of the Le Mans region (northern France), is known from a handful of well-preserved specimens. The lectotype (MNHN B16565) is well-preserved, retains both chelipeds as well as portions of the thoracic sternum and walking legs and shows exposed pleurites.Published as part of Van Bakel, Barry W. M., Guinot, Danièle, Artal, Pedro, Fraaije, René H. B. & Jagt, John W. M., 2012, A revision of the Palaeocorystoidea and the phylogeny of raninoidian crabs (Crustacea, Decapoda, Brachyura, Podotremata) 3215, pp. 1-216 in Zootaxa 3215 (1) on page 95, DOI: 10.11646/zootaxa.3215.1.1, http://zenodo.org/record/524864
Computational identification and analysis of protein short linear motifs
No full textShort linear motifs (SLiMs) in proteins can act as targets for proteolytic cleavage, sites of post-translational modification, determinants of sub-cellular localization, and mediators of protein-protein interactions. Computational discovery of SLiMs involves assembling a group of proteins postulated to share a potential motif, masking out residues less likely to contain such a motif, down-weighting shared motifs arising through common evolutionary descent, and calculation of statistical probabilities allowing for the multiple testing of all possible motifs. Much of the challenge for motif discovery lies in the assembly and masking of datasets of proteins likely to share motifs, since the motifs are typically short (between 3 and 10 amino acids in length), so that potential signals can be easily swamped by the noise of stochastically recurring motifs. Focusing on disordered regions of proteins, where SLiMs are predominantly found, and masking out non-conserved residues can reduce the level of noise but more work is required to improve the quality of high-throughput experimental datasets (e.g. of physical protein interactions) as input for computational discovery
Questionnaires in clinical trials: guidelines for optimal design and administration.
No full textA good questionnaire design for a clinical trial will minimise bias and maximise precision in the estimates of treatment effect within budget. Attempts to collect more data than will be analysed may risk reducing recruitment (reducing power) and increasing losses to follow-up (possibly introducing bias). The mode of administration can also impact on the cost, quality and completeness of data collected. There is good evidence for design features that improve data completeness but further research is required to evaluate strategies in clinical trials. Theory-based guidelines for style, appearance, and layout of self-administered questionnaires have been proposed but require evaluation
Possibilities and testing of CPRNG in block cipher mode of operation PM-DC-LM
No full textThis paper discusses the chaotic pseudo-random number generator (CPRNG), which is used in block cipher mode of operation called PM-DC-LM. PM-DC-LM is one of possible subversions of general PM mode. In this paper is not discussed the design of PM-DC-LM, but only CPRNG as a part of it because designing is written in other papers. Possibilities, how to change or to improve CPRNG are mentioned. The final part is devoted for a little testing of CPRNG and some testing data are shown. © 2016 Author(s)
FIG. 3. — Unprepared phosphatic nodule containing Lithophylax trigeri A in Lithophylax trigeri A. Milne-Edwards & Brocchi, 1879 from the French Cretaceous (Cenomanian) and placement of the family Lithophylacidae Van Straelen, 1936 (Crustacea, Decapoda, Brachyura)
No full textFIG. 3. — Unprepared phosphatic nodule containing Lithophylax trigeri A. Milne-Edwards & Brocchi, 1879, frontal view; Gazonfier quarry, Le Mans (Sarthe); Cenomanian; coll. Guéranger, MHN LM 2005.1.14. Scale bar: 5 mm.Published as part of Guinot, Danièle & Breton, Gérard, 2006, Lithophylax trigeri A. Milne-Edwards & Brocchi, 1879 from the French Cretaceous (Cenomanian) and placement of the family Lithophylacidae Van Straelen, 1936 (Crustacea, Decapoda, Brachyura), pp. 591-633 in Geodiversitas 28 (4) on page 597, DOI: 10.5281/zenodo.466548
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