132,896 research outputs found
Gedichte / von Nicolaus Lenau [d. i. Nikolaus Niembsch Edler von Strehlenau]
No full textGEDICHTE / VON NICOLAUS LENAU [D. I. NIKOLAUS NIEMBSCH EDLER VON STREHLENAU]
Gedichte / von Nicolaus Lenau [d. i. Nikolaus Niembsch Edler von Strehlenau] (1)
Cover (1)
Title page (3)
Titelblatt (8)
Erstes Buch - Gedichte (10)
Erstes Buch - Reiseblätter (83)
Erstes Buch - Vermischte Gedichte (135)
Erstes Buch - Vermischte Gedichte. Neue Folge (161)
Zweites Buch - Gestalten (169)
Zweites Buch - Liebesklänge (199)
Zweites Buch - Sonette (211)
Zweites Buch - Vermischte Gedichte (218)
Zweites Buch - Vermischte Gedichte. Neue Folge (271)
Zweites Buch - Waldlieder (289)
Größere lyrisch-epische Dichtungen (298)
Dichterischer Nachlaß (375)
Lyrische Nachlese (401)
Inhalt (422
- Meinhere d. J. (Edler) an Bistum Paderborn - 1036-12-31
No full textArchivsignatur: Paderb. Fm. Nr.13{'name': 'DFG', 'uri': 'dfg.png'
Willingness to approach behavior and feed disappearance of weaned pigs following vaccination with Mycoplasma hyopneumoniae vaccines
No full textFangman, T.; Baumert, D.; Dubois, P.; Edler, R.. (2008). Willingness to approach behavior and feed disappearance of weaned pigs following vaccination with Mycoplasma hyopneumoniae vaccines. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/154097
Comparison of 1 and 2 dose vaccination regimens using three currently licensed Mycoplasma hyopneumoniae vaccines in pigs
No full textBaysinger, A.; Polson, D.; Edler, R.; Philips, R.; Diaz, E.. (2008). Comparison of 1 and 2 dose vaccination regimens using three currently licensed Mycoplasma hyopneumoniae vaccines in pigs. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/154081
Performance of conventional health pigs vaccinated with Ingelvac MycoFLEX® or Suvaxyn® RespiFend
No full textKolb, J.; Johnson, D.; Diaz, E.; Edler, R.. (2008). Performance of conventional health pigs vaccinated with Ingelvac MycoFLEX® or Suvaxyn® RespiFend. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/154091
Comparative safety of two Salmonella choleraesuis vaccines in swine
No full textHusa, J.; Edler, R.; Saltzman, R.; Holck, J.T.; Walter, D.. (2005). Comparative safety of two Salmonella choleraesuis vaccines in swine. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/157555
Thymidylate synthase expression in colorectal cancer : its role as a prognostic factor and a predictive factor in adjuvant 5-fluorouracil-based chemotherapy
No full textThe enzyme thymidylate synthase (TS) plays a central role in DNA synthesis and is therefore an important target for chemotherapeutic treatment. We have studied the prognostic value of immunohistochemically detected TS on slices of formalin-fixed. paraffin embedded stored colorectal tumors using the monoclonal antibody TS 106. The level of TS staining in 25 primary colorectal cancers, arbitrarily scored in grades of 0, 1,2, and 3, correlated with enzyme activity, as measured by a tritium release method. TS was homogenously expressed in two thirds of 48 studied primary colorectal tumors. TS expression, assessed in 70 primary colorectal cancers Dukes' stage A-D, was an independent prognostic factor for time to death in colorectal cancer (p=0.04). Low TS expression (TS grades 0 or 1) correlated with better outcome and high TS expression (TS grades 2 or 3) with worse outcome. 243 patients with rectal cancer Dukes' stage A-C were retrospectively studied. Multivariate analysis showed that TS expression was an independent marker for loco-regional recurrence (p=0.04), distant metastasis (p=0.01) and overall survival (p=0.02).The predictive value of TS expression was studied in colorectal cancers of Dukes' stage B and C from 862 patients who all were included in Nordic adjuvant trials evaluating the efficiency of adjuvant 5- fluorouracil (5-FU) -based chemotherapy. No benefit of adjuvant chemotherapy was found in this group of patients, which was a subgroup of the 2191 included in randomized Nordic studies. In our study group, TS expression was an independent factor for disease-free survival (p=0.05) and overall survival (p=0.05). In the group of 442 patients treated with surgery only, TS expression was an independent prognostic factor (disease-free survival, pConclusions: TS levels, immunohistochemically assessed in colorectal cancer, are a prognostic factor independent of Dukes' stage. Patients with Dukes' C tumors with low TS expression, as determined by immunohistochemistry, will, according to our findings, have an impaired survival if they are treated with surgery and 5-FU -based adjuvant chemotherapy compared with surgery alone. Further studies in new patient material are needed to see whether the results of the present study can be reproduced. If this is the case, 5-FU -based adjuvant treatment is to be recommended only to high TS expressors, but not to low TS expressors.List of scientific papersI. Edler D, Blomgren H, Allegra CJ, Johnston PG, Lagerstedt U, Magnusson I, Ragnhammar P (1997). "Immunohistochemical determination of thymidylate synthase in colorectal cancer--methodological studies" Eur J Cancer 33(13):: 2278-81 https://pubmed.ncbi.nlm.nih.gov/9470819II. Edler D, Kressner U, Ragnhammar P, Johnston PG, Magnusson I, Glimelius B, Pahlman L, Lindmark G, Blomgren H. (2000). "Immunohistochemically detected thymidylate synthase in colorectal cancer: an independent prognostic factor of survival." Clin Cancer Res 6(2): 488-92. https://pubmed.ncbi.nlm.nih.gov/10690528III. Edler D, Hallstrom M, Johnston PG, Magnusson I, Ragnhammar P, Blomgren H (2000). "Thymidylate synthase expression: an independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer Clin" Clin Cancer Res. 6(4): 1378-84 https://pubmed.ncbi.nlm.nih.gov/10778966IV. Edler D, Glimelius B, Hallström M, Jakobsen A, johnston PG, Magnusson I, Ragnhammar P, Blommgren H (1970). "Thymidylate synthase expression in colorectal cancer - a prognostic and predictive marker of benefit from adjuvant flourouracil - based chemotherapy" (Submitted)V. Edler D, Hallström M, Ragnhammar P, Blomgren H (1970). "Intratumoral thymidylate synthase expression and proliferation in rectal cancer, assessed by Cyclin A and Ki-67 expression" (Manuscript)</p
Removal of dietary antimicrobials during oral vaccination does not decrease wean-to-finish productivity
No full textLawrence, B.V.; Edler, R.; Schwartz, K.; Walter, D.; Holck, T.; Musselman, M.. (2006). Removal of dietary antimicrobials during oral vaccination does not decrease wean-to-finish productivity. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/157267
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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