7 research outputs found

    Assessment of total antioxidant capacity and antimicrobial activity of Glycyrrhiza glabra in saliva of HIV-infected patients

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    Objectives: The objectives of this study were to evaluate the antimicrobial activity and total antioxidant capacity (TAC) of licorice in Saliva of HIV/AIDS patients. Materials and Methods: Saliva specimens were collected from 20 people living with HIV infection, with CD4 count <500 cells/mm3 from people infected with HIV/AIDS in Mangalore city, India. A combination of amoxicillin-clavulanic acid and nystatin was taken as the positive control and normal saline as negative control. Results were compared using one-way analysis of variance followed by Tukey's post hoc analysis in SPSS 19. Results: The TAC was evaluated spectrophotometrically at 695nm using the phosphomolybdenum method. Glycyrrhiza glabra showed a statistically significant reduction (P < 0.05) in total Candida count. The TAC of G. glabra was found to be 4.467 mM/L. Conclusions: G. glabra extracts showed good anticandidal activity and also high antioxidant property which reduces the oxidative stress of HIV-infected people

    Prevalence of oral fluorosis in Luangwa district of Lusaka Province, Zambia

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    Background: A fluorosis is a chronic form of hypoplasia of the dental enamel initiated by consumption water with high fluoride content during the time of tooth formation. Excessive ingestion of fluoride can result in fluorosis (mottling) of enamel which presents as opaque or white areas, lines, or flecks in the enamel surface. These teeth are more prone to dental caries and can be cosmetically disfiguring when they occur on anterior teeth. In spite of this fact, no study has been conducted to measure the prevalence of fluorosis in Luangwa district of the Eastern Province of Zambia. Aim: The study was to determine the prevalence of fluorosis and its treatment needs among the population affected in Luangwa district in the Eastern Province of Zambia. Methodology: A cross-sectional study was conducted with outreach descriptive survey and was conducted on patients that attended dental care during the mobile hospital outreach that was conducted in Luangwa district of Lusaka Province of Zambia. Results: Out of the total of 195 subjects examined, 56 (28.8%) patients were seen in Luangwa district clinic, out of which 1 (1.78%) had fluorosis. In Mwavi, at the secondary school, 71 (36.4%) were seen and 29 (40.84%) had fluorosis. At Luangwa Secondary School, a total of 68 (34.87% of the total subjects) were examined and out of that 7 (10.29%) had fluorosis. An aggregated total of 37 (18.97%) subjects of the 195 seen had fluorosis. Conclusion: The survey could elicit the presence of fluorosis in the Luangwa district of Lusaka Province. The baseline data suggest that the subjects who were seen from the clinic in the cannabidiol exhibited low levels (1.78%) of fluorosis because the water they consumed was treated by the local authority as compared to high prevalence of fluorosis in other sites outside the district where the water source was primarily river and wells which lacked treatment. Clinical Significance: This pilot study suggests the need to conduct a larger research study on the prevalence and impact of fluorosis in the population. This would help to plan future upstream dental public health programs

    Role of Dental Professionals in Tobacco Control

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    Tobacco use is the leading preventable cause of death in the world. Dentists have a professional responsibility in helping patients quit tobacco and to promote tobacco prevention and control strategies, as a routine component of dental practice. Dental professionals have a key role to play as a member of an inter-disciplinary health professional team, where each member delivers a consistent tobacco use cessation message. It is imperative that tobacco use cessation services are an integral part of oral health services
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