1,721,072 research outputs found
Indagini morfologiche ed immunoistochimiche sulle neoplasie testicolari del cane
No full textA retrospective survey on a color of 232 dogs submitted to the Department of Veterinary Anatomic Pathology for necropsy revealed that testicular tumors in dogs are frequent and the seminoma is one of the most represented tumor in this species. In addition this finding suggested that, as reported in men, testicular tumor in dogs have increased during the last years.
Since Seminoma is one of the most common tumor in man, it was hypothesized that the dog might represent a good animal model for the study of human seminoma. In human, two type of seminoma are described: the spermatocytic seminoma, that derives from mature spermatocytes and demonstrates benign behaviour, and the classical seminoma, that arises from undifferentiated seminal germ cells (i.d. gonocytes), is more malignant and frequently metastasized. In order to study the frequency of these two type of seminoma in the dogs, 43 testicular tumor with a previous diagnosis of seminoma were evaluated histologically with haematoxylin and eosin and periodic-acid Schiff (PAS) stains and immunohistochemically with an antibody directed against Placental Alkaline Phosphatase (PLAP) antigen, a marker of gonocytes. This study demonstrated the presence of two type of seminoma, classical and spermatocytic, in canine species and demonstrated that canine seminomas share morphological, histochemical and immunohistochemical features with the human counterpart. In addition, the occurrence of Carcinoma in situ (CIS, Seminoma precursors lesions) was demonstrated also in the dog.
Carcinoma in situ (CIS ) has been considered as a part of a human male reproductive disorder defined Testicular dysgenesis syndrome (TDS). TDS comprehend a wide spectrum of clinical and histopathological disorders. In addition, it has been suspected that environmental pollutants oestrogen-like or anti-androgenic activity may play a role in the pathogenesis of TDS. In order to evaluate the occurrence of TDS in dogs, all the testes submitted to the histopathology service from 2006 have been examined morphologically for the presence of histological features of TDS and immunohistochemically with anti-PLAP antibody for the presence of CIS.
Finally, stated the important role of oestrogen and its receptors in prostatic growth and differentiation and progression of prostatic carcinoma in human being, the expression of oestrogen receptors in normal, hyperplastic and neoplastic canine prostates has been evaluated. A progressive loss of oestrogen receptors expression in hyperplastic and neoplastic canine prostate and may account for the high degree of de-differentiation of canine prostatic carcinoma
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Spectral behaviour analysis of chirped fibre Bragg gratings for optical dispersion compensation
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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