65 research outputs found
Influence of kinship and familiarity on social and reproductive behavior of female mongolian gerbils
Naltrexone effects on socially-mediated food preferences and consumption of gerbils (Meriones unguiculatus)
Exposure to a hypogeomagnetic field or to oscillating magnetic fields similarly reduce stress-induced analgesia in C57 male mice
Effects of magnetic field exposure on open field behaviour and nociceptive responses in mice
Kinship and familiarity as factors affecting social transfer of food preferences in adult mongolian gerbils (Meriones unguiculatus)
Pain perception and electromagnetic fields
A substantial body of evidence has accumulated showing that exposure to electromagnetic fields (EMFs) affects pain sensitivity (nociception) and pain inhibition (analgesia). Consistent inhibitory effects of acute exposures to various EMFs on analgesia have been demonstrated in most studies. This renders examinations of changes in the expression of analgesia and nociception a particularly valuable means of addressing the biological effects of and mechanisms underlying the actions of EMFs. Here we provide an overview of the effects of various EMFs on nociceptive sensitivity and analgesia, with particular emphasis on opioid-mediated responses. We also describe the analgesic effects of particular specific EMFs, the effects of repeated exposures to EMFs and magnetic shielding, along with the dependence of EMF effects on lighting conditions. We further consider some of the underlying cellular and biophysical mechanisms along with the clinical implications of these effects of various EMFs
Neonatal exposure to estradiol decreases hypothalamic allopregnanolone concentrations and alters agonistic and sexual but not affective behavior in adult female rats.
Exposure of developing female rats to estradiol during the perinatal period induced long-lasting dysregulation
of gonadal axis and decreased cerebrocortical and plasma concentrations of allopregnanolone. We have now
examined the effects of neonatal estradiol administration in female rats on hypothalamic allopregnanolone concentrations
and on exploratory, affective, agonistic and sexual behaviors as well as social learning. A single
administration of β-estradiol 3-benzoate (EB, 10 μg) on the day of birth resulted in a delay of vaginal opening,
acyclicity and ovarian failure. These alterations were associated with a significant decrease in the concentrations
of allopregnanolone in the hypothalamus at 21 and 60 days, but not at 7 days, after birth. Neonatal administration
of EB also increased agonistic behaviors in adult rats, such as dominant behaviors and following of an ovariectomized
intruder, while living attacks unaffected. EB-treated rats showed also an increase in anogenital
investigation, associated with a drastic reduction in spontaneous and induced female sexual behaviors (receptivity
and proceptivity). In contrast, neonatal administration of EB did not affect locomotor activity, anxiety- andmoodrelated
behaviors, the social transmission of flavor preferences, and seizures sensitivity. These effects of estradiol
suggest that it plays a major role in regulation of both the abundance of allopregnanolone and the expression
of agonistic and sexual behaviors, while failing to influence affective behaviors and social learning. Thus, the
pronounced and persistent decrease in hypothalamic allopregnanolone concentration may be related to themanifestation
of agonistic and sexual behaviors
Sex differences in conditioned taste aversion and in the effects of the exposure to a pulsed magnetic field in deer mice, Peromyscus maniculatus
Shielding, but not zeroing of the ambient magnetic field reduces stress-induced analgesia in mice
The effects of a cannabinoid indirect agonist on social and non-social behaviour in male mice
Cannabis use and cannabinoid drugs have been shown to affect social activity in both humans and animals. These social effects can be impairing or promoting and are possibly linked to whether the social environment is novel or familiar. The main aim of this research was to reveal some of the social and behavioural consequences resulting from enhancement of the cannabinoid tone in CD-1 mice. The indirect agonist used, URB597, showed a dose-dependent facilitation of a social recognition preference score at the middle dose of 0.1 mg/kg as well as reductions in both social recognition and social approach preferences scores at the high dose of 0.4 mg/kg. The enhancing effect of the 0.1 mg/kg dose appears limited to the 'social' aspect of social recognition since an object recognition test did not reveal any effect at that dose. The impairing effects of the 0.4 mg/kg dose on social preference scores seem to generalize to other forms of learning such as object and place recognition. An olfactory recognition test suggested that the results are not confounded by a URB597 mediated effect on olfaction. These results suggest that URB597 dose-dependently affects social and non-social cognitive behaviours in adult male mice
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