39,624 research outputs found
Ko Waikato-Maniapoto te iwi
No full textNō te ūnga mai o Tainui waka, i Whangaparāoa, ka tīmata i reira te tautapa haere a Tainui waka i tōna rohe, i tāna tere i Te Ika-ā-Māui. Nāwai rā ka tau ki tōna tumu i roto o Kāwhia Moana, Kāwhia Kai, Kāwhia Tāngata, i te taha hauāuru o Te Ika-ā-Māui. I roto i ngā rautau i muri mai i te ūnga o Tainui waka me ngā tūpuna i tere mai i te waka, ka tīmata ngā tūpuna te mātoro haere i te whenua hou me te whakanoho i ngō rātou whānau. Ka tupu i koneki ngā hapū me ngā iwi i heke mai i ngā waka. I roto i ngā tātai whakapapa o Tainu waka, e mārama mai ana ngā kāwai heke ki ngā iwi o Waikato me Maniapoto hoki. Ka whai mana ngā rangatira o ngā iwi nei i ngō rātou kāinga me ngā pānga whenua i noho ai rātou.
I hua tuatahi ai te iwi o Waikato-Maniapoto i roto i ngā pakanga me ngā whakaipoipotanga mo ngā kāinga me ngā pānga whenua, kai, moana hoki. Nā ngā pūkenga wānanga, pakanga hoki, i whakawehe, i kotahi ai rānei ngā iwi.
I te taenga mai o te Pākehā ki te pēhi i ngā tikanga a te Māori, ka huri te aro o te Pākehā ki te whakahau me te whakawai i ngā rātou tauira hou ki runga i ngā iwi.
Ka whakaturengia ngā ingoa o ngā tikanga hou, nā te Kāwanatanga Pākehā hou nei i whakamana, ā, i whakaū ngēnei tikanga hou kia pēhia ngā tikanga taketake ake a te Māori. Ka huri a Waikato-Maniapoto iwi ki te aru i ngā tauira hou ki te whakawhanake i ngā uri whakatupu i roto i te ao hou. Hoi, i mau tonu i a Waikato-Maniapoto te wairua me ngā tikanga i heke iho ki ngōna uri.
Ka whakaūngia te wairua me ngā tikanga o ngā mātua tūpuna ki roto i te tauira hou o te Kīngitanga. Ka mahi ngātahi te Kīngitanga me te iwi o Waikato-Maniapoto ki te whakatinana i tōna kaupapa, arā, hei pupuru i te toto; hei pupuru i te whenua; ā, hei pupuru i te mana Māori motuhake. I roto i te Kīngitanga nga
hanganga iwi hou i puta hei kōkiri i ngā rautaki whakawhanake i te iwi whānui i roto i te ao hou nei.
Huhua noa atu ngā uri o Waikato-Maniapoto i whai wāhi i runga i ngā tūranga whakawhanake i te iwi whānui mā te whakaū i te mana Māori motuhake i roto i te reo me ngā tikanga o Waikato-Maniapoto iwi me ngōna kaupapa. Ko te whakahua i ngā hononga iwi kia whai whanaungatanga, kia whai tūrangawaewae te whakatinanatanga o te whakapono ā-wairua nei ki ngā taonga tuku iho o Waikato-Maniapoto. Ka whai mana, ka tūturu te kīanga a Waikato-Maniapoto i roto i te whakamana a ngā uri i ngā kōrero whakapapa o te iwi o Waikato-Maniapoto me te whakamana i te kīanga nei i ngā reanga whakapapa
Organizational Learning and Marketing Capability Development: A Study of Charity Retailing Operation of British Social Enterprises
No full textSocial enterprise is a hybrid form of profit- and social benefit-seeking organization whereby traditional nonprofit organizations pursue both their social mission and business opportunities. To embrace this new strategic direction shift, the nonprofit organizations need to develop new competences that will enable them to respond to the changes in the business model. The article investigates the learning mechanisms through which social enterprises develop a marketing capability to deploy their resources in the marketplace as the drivers of competitive advantage in their commercial practice. We study eight cases of UK-based charity retailers, in order to address the role of knowledge accumulation, articulation and codification process in the evolution of marketing capability development. We identify, amongst other things that the critical process of organizational learning for social enterprise is to transfer the experience into organization specific knowledge under the social aspects of constraints
KO-PLTs contain much less HMGB1 than GFP-PLTs.
No full textA, B: HMGB1 expression in the platelets of HMGB1-KO mice (KO-PLT); C, D: HMGB1 expression in the platelets of GFP mice (GFP-PLT); B, D: Enlarged images of the box areas in the image A and C. E: Semi-quantification of positively stained platelets with HMGB1 confirms the results of immunostaining showing that only a few (~7%) platelets in HMGB1-KO mice are positively stained with HMGB1 compared to more than 86.8% of platelets in GFP mice were positively stained with HMGB1. *P < 0.01 (GFP-PLT vs. KO-PLT). Green bars: 50 μm; Yellow bars: 10 μm.</p
Role of early maternal environment on limbic NPY-1R effects on behavior and metabolism in KO conditional mice
No full textIl neuropeptide Y (NPY) è un peptide di 36 aminoacidi, maggiormente presente nel sistema nervoso centrale, in particolare nel sistema limbico e nell’ipotalamo, ed è implicato in numerose funzioni tra le quali il controllo del comportamento alimentare ed emozionale, la risposta allo stress e l’ assunzione di etanolo.
Il progetto della mia tesi ha esaminato il ruolo dell’ambiente materno precoce sugli effetti del sistema NPY-Y1R limbico su comportamento e metabolismo in topi KO condizionali. Nel modello murino KO condizionale per il recettore Y1R , la delezione genica è controllata nello spazio e nel tempo attraverso il sistema doxiciclina-dipendente della CRE-ricombinasi , la delezione è ristretta selettivamente ai neuroni di alcune regioni del proencefalo quali amigdala, striato, ippocampo e nucleo arcuato ipotalamico. Alla nascita gli animali sono stati dati in adozione a madri di ceppo C57BL/6J e FVB/J, che presentano due diversi livelli di cura materna.
Il primo obiettivo specifico è stato quello di analizzare il comportamento materno dei due ceppi per valutare quantitativamente il comportamento materno utilizzando tecniche di osservazione etologica.
Il secondo obiettivo è stato quello di esaminare il fenotipo comportamentale e metabolico attraverso il monitoraggio del peso e specifici test comportamentali (Test dell’anedonia, Open Field (OF), Social Open Field (SOF), Tree Chamber Sociability and Social Novelty Test) per entrambi i sessi. I maschi sono stati sottoposti a dieta ipercalorica ad alto contenuto di grassi per verificare la vulnerabilità ad obesità e disordini metabolici associati, tramite monitoraggio del peso corporeo e del consumo di cibo, test di tolleranza al glucosio (Glucose tollerance test - GTT) e analisi del tessuto adiposo. Le femmine, invece, sono state esaminate per comportamento e successo riproduttivo.
I risultati della mia tesi indicano che il sistema NPY-1R ha un ruolo importante nella modulazione del comportamento ansioso e sociale, come emerge dalla minore attività locomotoria in risposta ad ambienti nuovi e minore permanenza in prossimità di stimoli sociali non familiari dei topi maschi sperimentali (KO). Inoltre, questi effetti del genotipo sono evidenti soltanto quando gli animali sono allevati in un ambiente materno precoce caratterizzato da alte cure materne. Ho verificato, poi, come Y1R sia implicato nel bilancio metabolico energetico e nel controllo metabolico nei maschi (ma non nelle femmine), come emerge dal dato sui minori livelli di peso corporeo associati a minore tessuto adiposo viscerale e sottocutaneo nei topi KO rispetto ai topi controllo (WT), quando allevati da madri adottive ad alta cura materna (FVB). L’esposizione a dieta ipercalorica annulla invece questo effetto dell’inattivazione di NPY1R. Le femmine non sembrano risentire di alcun effetto dell’inattivazione condizionale di NPY1R limbico se non quando impegnate nella riproduzione. Ho infatti osservato che le femmine KO, indipendentemente dall’adozione, hanno un successo riproduttivo minore rispetto alle femmine di controllo e presentano minori livelli di cura materna. Questo effetto non sembra dipendere da deficit di bilancio energetico, poiché l’esposizione ad una dieta ricca di grassi durante la gravidanza non aumenta la sopravvivenza della prole delle femmine KO. Neuropeptide Y (NPY) is a 36-amino acid peptide, largely present in the central nervous system, particularly in the limbic system and in hypothalamus, and that is implicated in several functions such as homeostasis control, feeding and emotional behaviors, in stress response and ethanol intake.
My thesis project was aimed to verify the role of early maternal environment on the effects of NPY-Y1R limbic on behavior and metabolism in conditional KO mice. In this murine model conditional KO for Y1R receptor, genic inhibition is controlled in space and time by doxiciclina-dependent system of recombinase-CRE; the deletion is selectively restricted to the neurons of some proencephalon regions such as amygdala, striatum, hippocampus and hypothalamic arched nucleus. Mice were monitored from the very first day of life (PND 0) and were fostered to C57BL/6J and FVB/J dams, showing different levels of maternal care.
The first aim was to verify the different levels of maternal behavior displayed by foster dams of different mouse strains by means of an ethological observation.
The second aim was to examine the behavioral and metabolic phenotype by constant monitoring of body weight and administration of behavioral tests (Anhedonia Test, Open Field (OFT), Social Open Field (SOFT), Tree Chamber Sociability and Social Novelty Test) in both sexes. Afterwards, males were exposed to a high fat diet and monitored for their body weight and food intake and metabolic parameter, including the Glucose Tolerance Test (GTT) and analysis of adipose tissues. Females were bred to evaluate their metabolic and / or psychological response to a reproductive challenge.
The results of my thesis indicate that the NPY-1R system plays a crucial role in the regulation of anxiety-like and social behavior, as revealed by the lower levels of locomotor activity in response to novel environments and the lower preference for unfamiliar social stimuli in KO males mice Interestingly, the effects of conditional NPY1r inactivation were present only when mice were reared by dams with high levels of maternal care and only in males. My experiment has also demonstrated that NPY1R is implicated in the regulation of energy balance only in males (but not in females), as revealed by the observation that KO mice weighted less and had less visceral and subcutaneous adipose tissue compared to WT mice, only when fostered to FVB dams. Exposure to a high fat diet eliminated this effect of NPY1R inactivation. Females did not show any effect on the NPY1R limbic conditional inactivity, unless they were exposed to a reproductive challenge. I observed that, regardless of foster dams’ strain, KO females had a lower reproductive success and levels of maternal behavior compared to WT. This effect probably does not depend on alteration of energy balance, as exposure to a high fat diet throughout pregnancy did not increase the KO females’ reproductive success
The people behind the papers – Jason Ko and Daniel Lobo
No full textPlanarians grow when they are fed and shrink during periods of starvation. However, it is unclear how they maintain appropriate body proportions as their size changes. A new paper in Development investigates the differences between growth and shrinkage dynamics and builds a mathematical model to explore the mechanisms underpinning these two processes. To learn more about the story behind the paper, we caught up with first author, Jason Ko, and corresponding author, Daniel Lobo, Associate Professor at the University of Maryland.https://doi.org/10.1242/dev.20298
Ko au te whenua, te whenua ko au – I am the land, the land is me: An autoethnographic investigation of a secondary school teacher’s experience seeking to enrich learning in outdoor education for Māori students.
No full textThis thesis is my story as an outdoor educator, as a researcher, and a co-participant reflecting on my own actions and experiences as well as those of my students. In this autoethnography I share my revelations and tensions in my role as an outdoor education teacher seeking to enrich the experiences of Māori students. Māori culture and history have largely been ignored in the outdoor education classrooms and environments of Aotearoa New Zealand. After teaching the subject for ten years I didn’t perceive that I was perpetuating the same invisibility in my own outdoor education course. Over this time a number of questions that had fermented at the back of my mind came to the fore; ‘why are so few Māori students opting to take outdoor education as a senior secondary school subject?’ and ‘how can I make the subject of outdoor education more desirable and appealing to Māori?’ A place-responsive approach incorporates and values traditional ways of learning through the notion of place and the stories attached to them. The cultural context of learning about and through place has the potential to provide learning opportunities that are relevant and meaningful to all learners but particularly Māori. Place-responsive pedagogies allow outdoor educators to create an environment where language, knowledge, culture and values are normal, valid and legitimate – contexts where Māori students can be themselves. Through this research I have found that the implementation of a place responsive approach has had significant implications for Year twelve outdoor education at Mount Maunganui College. The improvement in Māori student achievement and numbers selecting the subject have been affirming.
Ko au te whenua, te whenua ko au – I am the land, the land is m
Long term trend of chemical oxygen demand in Saroma-ko Lagoon, Japan; possible effects of climatic warming
No full textA trend of shortening duration of ice coverage has been reported in many rivers, ponds and lakes around the world due to climatic warming. The shortening will have much influence on organic production due to the greater supply of light intensity and hence on water quality. Chemical Oxygen Demand (COD), a useful measure of water quality, has been monitored over the past thirty years in Saroma-ko Lagoon, a boreal lake in Japan characterized by wintertime ice coverage. Here the data set of water quality in the lagoon is analyzed to reveal long-term trends in COD and the influence of climatic warming on such trends. There has been a significant increasing trend, caused primarily by an abrupt increase in the early 1990s. However, the increase could not be explained by the increased load of organic matter on the lagoon from the river basin and organic production in the lagoon. On the other hand, periods of freezing of the entire surface have tended to be shorter with inevitable thinning of ice over the past forty years, probably due to climatic warming. Ice and planktonic algae are exposed to the low light intensity in situ, which is not optimum for the algal production of organic matter. The shortening and thinning should thus bring an improvement in ambient light conditions for algae, resulting in an increase of organic matter in winter. Most of the organic matter possibly remains even after spring because of the low water temperature. It is highly possible that climatic warming promotes deterioration in water quality in ice-covered lakes
Extending product lifetimes: a reuse network for ICT hardware
No full textThis paper examines how a network of small/medium-sized enterprises was developed to enable reuse and resource conservation in the information and communications technology sector by exchange of used equipment over a resource exchange internet platform. The network’s effectiveness and potential for expansion is also examined. The results demonstrate that it is possible and in many cases economically viable to increase the reuse stream of equipment and to extend the network’s activities to a European level. The expectation of doubling the amount of traded appliances within the network was greatly exceeded. The successful development of technical, legal and financial guidance led to its incorporation into an accredited industry guideline
Ko au ko te taiao, ko te taiao ko au – I am the environment and the environment is me: A Māori theology of the environment
No full textKo au ko te taiao, ko te taiao ko au – I am the environment and the environment is me. This article will present a Māori theology of the environment based on whakapapa (genealogy), whenua (land), wairua (spirit), whānau (family), and whakapono (faith)
Ko Rangitoto, Ko Waitematā: Cultural Landmarks for the Integration of a Māori Indigenous Psychotherapy in Aotearoa
No full textRangitoto is one of many small islands within the Hauraki Gulf which sits at the entrance to the Waitematā harbour. Rangitoto was formed through a series of seismic eruptions approximately 600 years ago when liquid lava cooled, quickly forming a naturally occurring volcanic glass known as obsidian. Set between the layers of volcanic ash are human footprints bearing testament that local Māori of that time witnessed the formation of Rangitoto. Waitematā is one of two harbours surrounding Tamaki Makaurau covering 70 square miles of water, spreading out into the Hauraki Gulf before opening out to the mighty Pacific Ocean. Since the first settlement in the 13th century (Irwin & Walrond, 2012), Waitematā has been a navigator’s haven providing deep channels, slow currents and a safe tidal range where the many residents of Tamaki Makaurau and visitors from afar have enjoyed and admired the beauty of both Rangitoto and the Waitematā. Rangi toto refers to the luminous blood-like sky created by the volcanic eruption. Wai te matā refers to the dark sparkling waters created by the reflective glass like obsidian (McLintock, 1966). In this article, I draw upon Rangitoto and Waitematā as natural and cultural landmarks for the integration and application of a Māori whakapapa construct in clinical and therapeutic practice. Appropriately, Rangitoto and Waitematā together provide a silhouette of both figure and ground for a Māori indigenous psychotherapy approach and a construct for developing cultural competence in Aotearoa New Zealand. In doing so, I discuss firstly, the importance of understanding whakapapa as a social and whānau systems construct; secondly, the relevance of understanding and integrating Māori methods in the practice of psychotherapy; and thirdly, Pūrākau, an indigenous Māori storytelling approach, which is relevant in the therapeutic setting.
Waitara
Ko Rangitoto tētahi o ngā moutere ririki maha kei te whanga o Hauraki ā, e noho nei i te wahapū o te Waitematā. I ahua ake a Rangitoto mai i ngā rū o te whenua e ono rau tau nei pea ki muri, arā nō te mātaohanga o te puia ko tōna otinga ko te tūhua. Kei waenga o ngā paparanga puia he tapuwae tangata, te whakaaturanga o te kiteatangahia e te kanohi Māori te ahunga ake o Rangitoto. Ko Waitematā tētahi o ngā whanga e rua e tāwharau ana i a Tāmaki Makaurua. E whitu tekau pūtakerua maero te takotoranga wai tere atu ki Hauraki i mua i te rerenga atu ki te Moana-nui-ā-Kiwa. Mai i te nohoanga tuatahi i te rautau tekau mā wha, he wāhi ruruhau mō ngā kaiwhakatere waka na ana taiawa hōhonu, taiawa āta rere, ā, he tai haumaru. He wāhi kaingākauhia e te marea noho i reira, e ngā manuhiri o tawhiti, whakamīharo atu hoki ki te ātaahua o Rangitoto rāua tahi ko Waitematā. He tohu te ingoa Rangi-toto ki te pīataatanga rite ki te toto o te rangi i te pahūtanga o te puia. Ko Wai-te-matā, e whakapā ana ki ngā wai pīataata mai i te ātanga o te tūhua. I roto i tēnei tuhinga, ka huri au ki a Rangitoto rāua ko Waitematā hei maunga hei awa whakapapa whakauru whakahāngai i te whakapapa Māori ki ērā o ngā āhuatanga whakapāatukingāmahihaumanu. HetikatonukiatūmaiaRangitotorāuakoWaitematā hei whakaratonga āhua hanga, pouhere hoki mō te ara hai whakaora hinengaro Māori, ā, me tētahi hua whakahiato mātauranga ahurea i Aotearoa. Koia nei, ka whakaara ahau, tuatahi i te take nui me mātatau ko te whakapapa hei hanga pūnaha hāpori whānau hoki; tuarua, te pānga o te mātauranga ki te whakaurunga o te momo mahi a te Māori ki te mahi a te kaiwhakaora hinengaro; ā, tuatoru te Pūrākau, te ara kōrero paki a te Māori e hāngai nei ki te horanga haumanu
- …
