1,817 research outputs found
Douglas Haynes : The Toledo Series
No full textWilkin describes Haynes' approach to art history and investigates the relationship between Haynes' paintings and the work of El Greco. Feist writes a tribute to the work. Biographical notes
Harold Feist : Genesis of an Image
No full textWilkin traces colour-field painter Feist's career from 1971 to 1980, quoting frequently from the artist's correspondence. Extensive biographical notes. 14 bibl. ref
Abstraction x 4 : Joseph Drapell, Harold Feist, Douglas Haynes, Leopold Plotek
No full textIn her essay, Wilkin notes the influence of early abstract painters on works by Drapell, Feist, Haynes and Plotek. Biographical notes
Lincoln’s Funeral March
No full text80.7568.685a – “Lincoln’s Funeral March”: E. C. Davis: Leo Feist: 1909: Piano Solo
Entre Nós: entrevista a Nuno Feist e João Pereira Bastos
No full textEmissões - Entre NósPrograma “Entre Nós” - uma produção vídeo da Universidade Aberta para a RTPEntrevista ao maestro Nuno Feist e a João Pereira Bastos, diretor da Antena 2, realizada em dezembro de 2003.info:eu-repo/semantics/publishedVersio
Synthesis of 2-alkenyl-3-alkoxycarbonylfurans by 'Feist-Benary-cyclocondensation' of (2,4-dioxobutylidene)phosphoranes with chloroacetaldehyde and subsequent Wittig reactions
No full textFunctionalized furans were prepared by 'Feist-Benary-cyclocondensation' of (2,4-dioxobutylidene)phosphoranes with chloroacetaldehyde and subsequent Wittig reactions
Feist-Belmont History.
No full textHistory and development of the Feist-Belmont family originally from Frankfurt/Main with some historical background. Members of the family worked in the wine and metal business and in banking. Branches of the family spread to London, Paris, US, and Mexico. Also included are transcripts of letters pertaining to the family.The following families are mentioned in these manuscripts:Aahousen; Adler; Alvensleben; Bamberger; Bayer von; Becke von der; Begrow; Bellmann; Belmont; Berendt; Berg; Berlet; Bethmann; Beyer von; Birkenstock von; Bischoffsheim; Bishoff; Blum; Boch; Bohl; Brach; Brafoot; Buhlmann; Cadenbach; Cahen; Calderwell; Cana; Coster; Crevenna; Dresden; Dulong; Eggers; Ellison; Ellissen; Engelhardt; Ephraim; Erlanger von; Faerber; Faure; Feist; Fischer; Flavigny; Fleischel; Fluerscheim; Fluersheim; Fraenkel; Frankenberg von; Friedenthal; Fuld; Gabel; Gallifet; Gambetta; Gebhardt; Geiger; Getz; Godsche; Goldschmidt; Golliers; Goodridge; Gottheil; Graubner; Hammelbacher; Hanau; Heidelberger; Henoul; Henriques; Henschel; Hernsheim; Herz; Heyman; Hirsch; Hirschfeld; Hohenemser; Honey; Horschitz; Hummel; Igel; Jacobson; Jacoby; Jeramel; Jessel; Johannsen von; Koch; Koenigswarter; Koerbchen; Ladenburg; Lengerke; Leopold; Leunig; Levysohn; Lewes; Lieben; Liebeschuetz; Liebmann; Linnemann; Loldner; Lomas; Loos; Maass; Malzahn; Manskosch; Mappes; Mayer; Merton; Meyer-Berendt; Miederhofheim; Model von; Moller; Moltke von; Montefiore; Morpurgg; Mortiz; Mumm; Nathan; Oesterley; Offenbach von; Oppenheim; Oswald; Passavant; Pavlow; Peters; Petry; Philippart; Picard; Pini; Plaut; Pless; Prennen; Proudfoot; Reichenheim; Reinach von; Reiss; Rinz; Robertson; Roederer; Roosen; Sabel; Saling; Sanders; Sappus; Schackmayer; Schenk von; Schestowitz; Schiller; Schloss; Schoen; Schoenfeld; Schuback; Schulz; Schuster; Seligmann; Senden von; Simon; Speyer; Spiess; Stanley; Steffani; Stern; Stiebel; Stucken; Treitschke; Wachtel; Wahlendorff von; Walb; Weismann; Weisweiler; Winter; Wolff; Wollheim; Wuppermann; Ziegler; Zitschmann; Zueschen von.digitizedPart I: 1775-1877Part II: 1842-1859Part III: 1775-1882The author presented the manuscript to Robert Weltsch, London.part 3, 75 pages and transcripts of letters, 1860-1878; dedicated to Robert Weltsch, 1973. Addenda: Belmont-Feist History, part 1, 1775-1877; part 2, 1842-1859
Sequenzstratigraphische Interpretation der Kleinzyklen im Unteren Muschelkalk (Mitteltrias, Germanisches Becken)
No full textPhytoplankton associations of the Anisian Peri-Tethys Basin (Central Europe): Evidence of basin evolution and palaeoenvironmental change
No full textInvestigating the mode of action of fluensulfone on the plant parasitic nematode, Globodera pallida
No full textPlant parasitic nematodes (PPNs) are a major agricultural pest that infest crops and affect food production worldwide. Current measures that exist for controlling PPN infestation are limited, with the majority of chemical control agents being withdrawn from use due to their off-target toxicity and impact on the environment. New nematicides are therefore required for safe and improved PPN management strategies.
Fluensulfone (FLS) is a novel nematicide with a distinct profile of effects on PPN, suggesting a unique mode of action. Here, I investigate the effects of fluensulfone on G. pallida at two critical life cycle stages; the egg- and cyst-enclosed J2, and the free-living, non-feeding, infective J2.
Investigation of the ability of fluensulfone to inhibit G. pallida hatching, relative to the efficacy of other distinct classes of nematicides, reinforced that fluensulfone has a distinct mode of action among existing nematicides and demonstrated that it is a potent inhibitor of hatching. At concentrations as low as 1μM (0.29 ppm), fluensulfone exhibited complete inhibition of G. pallida root diffusate-induced hatching. This effect was reversible at concentrations ≤5μM (1.46 ppm), partially reversible at concentrations ≤50μM (14.6 ppm) and irreversible at the maximum concentration tested of 500μM (146 ppm). Despite hatching inhibition being reversible at low concentrations, J2s that emerged under these conditions exhibited impaired motility. This suggests that fluensulfone impacts on the viability of the unhatched J2. The irreversibility of hatch inhibition at concentrations >50µM coincided with a granulated appearance of the egg-encased J2 and suggests a nematicidal action of fluensulfone on the unhatched J2. To inform mechanistic understanding of the nematastatic and nematicidal action of fluensulfone, I combined inhibitor studies to highlight the role played by distinct metabolic fluxes and provide evidence that lipid utilization is selectively disrupted. This was reinforced using Coherent anti-Stokes Raman scattering (CARS) spectroscopy to image lipid stores.
I optimized approaches to extract major lipids from the PPN and probed for levels of key lipid. Interestingly, this failed to identify significant changes in the gross levels of lipids in G. pallida juveniles treated with fluensulfone. I discuss this mismatch.
The effects of fluensulfone on lipid utilization were accompanied by morphological changes, manifest by the appearance of enlarged, lipid-bound organelles. These highlight that fluensulfone impacts lipid and/or membrane trafficking processes, accumulating vacuole-like structures. The gross features of these effects appear to be consistent with degradative and cell death pathways. In particular, the appearance of these structures show striking similarities to the accumulation of degradative water and lipid filled vacuoles associated with the cell death process of methuosis.
Taken together, the data presented here present an increased understanding of the mode of action of fluensulfone. They support a model in which fluensulfone brings about a slowly developing metabolic insult that is nematicidal. This involves a disruption in lipid homeostasis and the nematicidal action of fluensulfone may be explained by the accumulation of toxic metabolic intermediates
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