898 research outputs found
Haematological risk factors for pregnancy outcome in Jamaican women with homozygous sickle cell disease
Objective: to examine the association between fetal outcome and the steady state haematology of mothers with homozygous sickle cell disease.Design: a retrospective observational study. The data were taken from dockets kept at the Sickle Cell Clinic and verified by interview with 45% of the patients.Setting: the Sickle Cell Clinic at the University Hospital of the West Indies or two peripheral clinics operated by the staff of the MRC Laboratories.Subjects: all women aged 14 years or older with homozygous sickle cell disease who had experienced at least one pregnancy in the period 1977 to 1986.Main outcome measures: three fetal outcomes including miscarriages, perinatal deaths, and birthweight.Results: there were 270 singleton pregnancies in 175 women with an overall fetal wastage of 32.2%. There was a significant increased risk of perinatal death with low maternal fetal haemoglobin level, but there were no haematological associations with miscarriages or birthweight.Conclusions: these data suggest that maternal steady-state haematology has little influence on fetal outcome, with the exception that mothers with high HbF levels are less prone to perinatal deaths. Further study is required to investigate acute haematological changes associated with pregnanc
Risk factors for proliferative sickle retinopathy
The prevalence, incidence, and risk factors associated with proliferative sickle retinopathy (PSR) were investigated in 786 patients with homozygous sickle cell (SS) disease and 533 patients with sickle cell haemoglobin C (SC) disease. PSR was more common in SC disease, in which there was a significant predominance of males, and it increased with age in both genotypes. In SC disease the risk of developing PSR was highest between 15 and 24 years in males, between 20 and 39 years in females, and in SS disease between 25 and 39 years in both sexes. PSR tended to be bilateral, especially in SC disease. There was no evidence of familial clustering of PSR in SC siblings, and insufficient numbers of SS siblings were available to test for clustering. Haematological risk factors associated with PSR in SS disease were a high haemoglobin in males and a low fetal haemoglobin in both sexes and in SC disease, a high mean cell volume, and a low fetal haemoglobin in female
Nouvelle méthode syntagmatique de vectorisation appliquée au self-organizing map des textes vietnamiens
@inproceedings{CN-NGUYEN-2004, author = {Nguyen D.T.}, title = {Nouvelle méthode syntagmatique de vectorisation appliquée au self-organizing map des textes vietnamiens}, booktitle = {RECIRAL'04}, year = {2004}, address = {Fès, Maroc}, month = {avril} }National audienc
Mapping the Landscape: A Bibliometric Analysis of CALIBER 2022 Convention Publications
The present study examines the authorship patterns, collaboration levels, and various other parameters such as gender, author designation, institutional affiliation, and geographical distribution of the conference papers presented at CALIBER 2022 by employing an array of bibliographic analysis techniques. The analysis is based on a dataset consisting of 45 papers authored by 100 individuals and found that authors hailing from Uttar Pradesh emerged as the foremost contributors. The study also found that universities emerged as the most prolific contributors, responsible for the publication of 71.00 per cent of the articles within the designated time frame
Vertical transmission of HIV-1: maternal immune status and obstetric factors. The European Collaborative Study
OBJECTIVE:
To estimate the effect of maternal factors and events around the time of delivery on HIV-1 vertical transmission risk.
DESIGN:
Prospective study.
SETTING:
Twenty-two obstetric and paediatric clinics in seven European countries.
PATIENTS OR OTHER PARTICIPANTS:
Mothers identified as HIV-infected before or at delivery and their children.
MAIN OUTCOME MEASURE:
Paediatric HIV infection.
RESULTS:
By November 1995, 1846 mothers with 1945 children had been enrolled. The vertical transmission rate was 16.4% (95% confidence interval, 14.5-18.3). Parity, maternal age, race, mode of HIV acquisition, injecting drug use and sex of infant were not statistically significantly associated with risk of transmission. Children delivered vaginally were more likely to be infected than those delivered by Caesarean section. However, in vaginal deliveries the procedures used, duration of ruptured membranes or length of second-stage labour were not related to transmission. Transmission increased almost linearly with decreasing CD4 cell count, but there was no such trend for CD8 cell count. Women with CD4 cell counts below 200 x 10(6)/l were significantly more likely to deliver early (chi 2 for trend, 14.02; P < 0.001). Very premature infants were at increased risk of infection, but after about 35 weeks gestation the transmission rate remained stable, with no increase in late pregnancy. This trend was confirmed after allowing for maternal CD4 cell count.
CONCLUSIONS:
The rate of vertical transmission increases linearly with decreasing maternal CD4 cell count. Women with fewer than 200 x 10(6) CD4 cells/l have an increased risk of premature delivery, which would affect timing of interventions. The stable transmission rate after 35 weeks gestation suggests little acquisition of infection during late pregnancy
Eastern Iran in the Achaemenid Period
The author deals with the archaeological evidence of the Achaemenid period in eastern Iran. This evidence is limited, rare and contradictory with regard to the historical importance of the eastern provinces of the Empire. The territorial extent of the Achaemenid Empire is ambiguous too and in this regard the cultural background of the different provinces, as well as relationships between center and periphery, were crucial factors affecting the visibility of the Achaemenid empire in its eastern-most regions. Similarly, the geographic definition of ‘eastern Iran’ requires clarification as well because, as a geomorphological unit. Thus at least four different aspects of interpretation should be considered when considering the evidence of the Achaemenid empire in the east:
1. the dynastic - identifiable by inscriptions, coins and seals
2. the ethnic - possibly detectable on both physical anthropological and cultural grounds
3. the political/imperial - recognizable both in macroscopic architectural and art historical remains and in the material traces of settlement patterns and economic investments, e.g. to secure the water supply
4. the chronological - interpretable in the differing horizons connected to the period of Achaemenid political-dynastic dominion in the area
Landscape design methods in architecture
Landscape has been used as a metaphor or conceptual reference for an increasing amount of excellent architectural projects in the last two decades. The phenomenon seems to be a substantial innovation of architecture with an interesting potential for artistic, social and ecological gains. To be able to better understand and critically review these projects, it is important to better understand the notion of landscape. How can we better understand the idea of landscape and its design methods for application in architecture? To answer this central question we try to find a working definition of relevant landscape design methods in this paper. Only thereafter may we ask how these landscape methods are applied to the theory and practice of architecture, and what knowledge can be derived from built examples for future practical and theoretical use in the field. This paper is part of the larger study ‘Architecture with Landscape Methods’ with more case studies. This paper however is mainly based on literature study. Currently the author is analyzing four crucial projects from 1990-present in CAD and GIS based analytical case studies. One or two of these cases will illustrate the subject to the audience in the author's poster presentation at IFLA2012.UrbanismArchitectur
'Resting' and 'Fremantle Terzinas' Poems by author Hersri Setiawan (Translation into English by David T. Hill)
In late February 1993, Indonesian author Hersri Setiawan arrived for a brief visit to Australia to participate in the Perth Writers' Festival at the Fremantle Arts Centre. A former political prisoner held for nine years in detention without trial, he managed to leave Indonesia several years ago and now lives in the Netherlands as a political exile. These poems have been translated by David T. Hill
Library Supported Scholarship: Increasing Faculty Scholarly Reach with Author Services
The directors of the departments of institutional research & training (Monica D.T. Rysavy, Ph.D.) and the Hirons Library and Learning Center (Russell Michalak, MLIS) at Goldey-Beacom College, a small private doctoral-granting institution, partnered to offer training workshops and professional development opportunities to faculty related to research and publication processes. We recently surveyed current faculty regarding their satisfaction, level of awareness, and desire for training regarding library and researcher services using Qualtrics. This presentation shared results from this survey and lessons learned from offering a workshop about how researchers can expand their online presence using author profiles
Lithium transport in crown ether polymers
A series of 12-, 13-, and 14-membered crown ether rings bearing polymerisable side-chains has been synthesised. The crown ethers were attached to a methacrylate or acrylate polymerisable group either via a short link (Ring-CH(_2)-O-Polymer) or via a spacer group. Both hydrocarbon and ethylene oxide spacer groups were used, giving structures of the form (Ring-CH(_2)-O-(CH(_2))(_6)-O-Polymer) and (Ring-CH(_2)-O-((CH(_2)CH(_2))(_2)O)-Polymer). The ethylene oxide chain can potentially bind to a Li(^+) dopant ion. The relative Li(+) binding affinity of 12-, 13-, and 14-membered mono- and disubstituted crown ethers has been assessed by variable temperature (^13)c and (^7)Li NMR. The crown ether bearing monomers were polymerised using standard free-radical polymerisation methods to yield amorphous materials whose glass transition temperature (T(_g)) was controlled principally by the nature of the spacer group. On doping with lithium triflate (LiCF(_3)SO(_3)), the polymers exhibit high ionic conductivity. The conductivity was primarily dependent on polymer T(_g), but was also found to be higher for 12-crown-4 based systems than for 13-crown-4 and 14-crown-4 based analogues. This behaviour was consistent with the results of the NMR studies, which showed that Li(^+) exchange occurs more readily between 12-crown-4 rings than 13- or 14-crown-4 rings. The NMR studies also showed that 12-crown-4 systems have a higher tendency to form 2:1 (ring : Li(^+)) complexes. Within a polymer matrix, the presence of 2:1 complexes allows Li(^+) migration via an association-disassociation mechanism, avoiding the high energy intermediate state of a free or weakly bound Li(^+) ion. The greater encapsulation provided by 2:1 complexation may also aid in ion pair separation
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