108,105 research outputs found
African origin of the malaria parasite Plasmodium vivax.
No full textPlasmodium vivax is the leading cause of human malaria in Asia and Latin America but is absent from most of central Africa due to the near fixation of a mutation that inhibits the expression of its receptor, the Duffy antigen, on human erythrocytes. The emergence of this protective allele is not understood because P. vivax is believed to have originated in Asia. Here we show, using a non-invasive approach, that wild chimpanzees and gorillas throughout central Africa are endemically infected with parasites that are closely related to human P. vivax. Sequence analyses reveal that ape parasites lack host specificity and are much more diverse than human parasites, which form a monophyletic lineage within the ape parasite radiation. These findings indicate that human P. vivax is of African origin and likely selected for the Duffy-negative mutation. All extant human P. vivax parasites are derived from a single ancestor that escaped out of Africa
Duffy, T, VX21879
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/382818Surname: DUFFY. Given Name(s) or Initials: T. Military Service Number or Last Known Location: VX21879. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 41047.222465
Item: [2016.0049.15111] "Duffy, T, VX21879
Duffy, T M, 406438
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/382808Surname: DUFFY. Given Name(s) or Initials: T M. Military Service Number or Last Known Location: 406438. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 34541.222455
Item: [2016.0049.15101] "Duffy, T M, 406438
Prevalence of <i>PvDBP</i> duplications in Duffy-positives (C/T and T/T) and Duffy-negative (C/C) individuals (<i>N</i> = 145) <i>based on PCR analysis</i>.
No full textPrevalence of PvDBP duplications in Duffy-positives (C/T and T/T) and Duffy-negative (C/C) individuals (N = 145) based on PCR analysis.</p
Review of Secular Mysteries: Stanley Cavell and English Romanticism by Edward T. Duffy
No full textReview of Secular Mysteries: Stanley Cavell and English Romanticism by Edward T. Duff
Educational Innovation in Politically Sensitive Fields: a case study of interview material involving the bereaved families of the Iraq Nasirya killings 12.11.2003
No full textThis 'in practice' article offers a brief 'snapshot' of a recent project we conducted in creating and teaching politically sensitive curriculum materials with university students, including future teachers, in Northern Ireland
Learning for design reuse
No full textOver the past decade 'design assistance', i.e. where the computer is viewed as an Intelligent Design Assistant (IDA) [MacCallum-etal85], has emerged in knowledge based design support and has formed the basic research strategy for the CAD Centre, University of Strathclyde, since the mid-80s. Within this philosophy, an IDA would act as a colleague to a designer, providing guidance, learning from past design experiences, carrying out semi and fully automated tasks, explaining its reasoning and in essence complementing the designer's own natural skills, and thus leaving the ultimate decision making, control and responsibility with the designer
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