7,796 research outputs found
The Independent Sign Bias: Gaining Insight from Multiple Linear Regression
No full textAs electronic data becomes widely available, the need for tools that help people gain insight from data has arisen. A variety of techniques from statistics, machine learning, and neural networks have been applied to databases in the hopes of mining knowledge
from data. Multiple regression is one such method for modeling the relationship between a set of explanatory variables and a dependent variable by fitting a linear equation to observed data. Here, we investigate and discuss some factors that influence whether the resulting regression equation is a credible model of the
data.Pazzani, Michael J. and Bay, Stephen D. (1999). "The Indepdendent Sign Bias: Gaining Insight from Multiple Linear Regression" Proceedings of the Twenty First Annual Conference of the Cognitive Science Society.This research was funded in part by the National Science
Foundation grant IRI-9713990
D. Michael Quinn
No full textBlack and white photograph of author D. Michael Quinn, probably around 198
D. Michael Quinn
No full textBlack and white photograph of author D. Michael Quinn, probably around 198
Dissertatio De Censu Augusti / Quam Sub Praesidio ... Dn. Ulrici Obrechti, In Alma Argentinensium Universitate Professoris Histor. ... Ad Examen Solenne Proponit Michael Förtsch/ Wertheimio-Francus Author. A. D. [...] Maii MDCLXXV.
No full textDISSERTATIO DE CENSU AUGUSTI / QUAM SUB PRAESIDIO ... DN. ULRICI OBRECHTI, IN ALMA ARGENTINENSIUM UNIVERSITATE PROFESSORIS HISTOR. ... AD EXAMEN SOLENNE PROPONIT MICHAEL FÖRTSCH/ WERTHEIMIO-FRANCUS AUTHOR. A. D. [...] MAII MDCLXXV.
Dissertatio De Censu Augusti / Quam Sub Praesidio ... Dn. Ulrici Obrechti, In Alma Argentinensium Universitate Professoris Histor. ... Ad Examen Solenne Proponit Michael Förtsch/ Wertheimio-Francus Author. A. D. [...] Maii MDCLXXV. (1)
Titelblatt (1)
Dissertatio De Censu Augusti (3
Interview with Michael Cronin
No full textMichael Cronin (Ph. D. Trinity College, Dublin). Author of the ground-breaking, Translating Ireland, (Routledge 1996) Michael Cronin is the foremost translation scholar working in Ireland today. Cronin established the cultural review Graph with Peter Sirr and Barra Ó Séaghdha in 1986 and was involved in the setting up of the Irish Translators Association and the creation of Ireland Literature Exchange, the body responsible for funding the translation of Iri..
LYRICOS : synthesis of singing voice using a sinusoidal model
No full textIssued as Final report, Project no. D-48-X46Final report has author: Michael Maco
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Advice to Students Considering Graduate Work in English
No full textDrawing on specific case histories from over 50 students who applied to graduate programs in English Literature, Composition, and Writing, this document represents my advice to students applying nationwide to do graduate work in the various subfields of English studies
Zinc inhibits human CIC-1 muscle chloride channel by interacting with its common gating mechanism
No full textThe definitive version is available at www.blackwell-synergy.comTransition metals block the muscle Cl channel ClC-1, which belongs to a large family of double-barreled Cl channels and transporters. In the Torpedo Cl channel ClC-0, Zn2+ block is closely related to the common gating mechanism that opens and closes both pores of the channel simultaneously, and the mutation C212S, which locks the common gate open, also eliminates the block. In ClC-1, however, previous results suggested that Zn2+ block is independent of gating, and that the cysteine residues involved in Zn2+ binding are in different positions to those that confer Zn2+ sensitivity on ClC-0. In this work, we show that Zn2+ block of ClC-1 is faster at hyperpolarized potentials where the channel is more likely to be in the closed state. Mutation C277S, equivalent to C212S in ClC-0, which locks the common gate in ClC-1 open, virtually eliminates Zn2+ block. A mutation, V321A, which reduces open probability of the common gate, facilitated Zn2+ block. These results demonstrate that Zn2+ block is state dependent, acting on the common gate. The extent of the block, however, is not a simple function of the open probability of the common gate. The Q10 of 13 of the time course of Zn2+ block, which is significantly higher than the Q10 of common gating transitions in WT ClC-1, suggests that Zn2+ binds to a very high temperature-dependent low-probability closed substate of the common gate, which has not yet been characterized in this channel.Michael D. Duffield, Grigori Y. Rychkov, Allan H. Bretag and Michael L. Robert
Clinical aspects of dental materials : theory, practice, and cases / Marcia Gladwin, Michael Bagby.
No full textRev. ed. of: Clinical aspects of dental materials / [edited by] Marcia Gladwin, Michael Bagby. 2nd ed. c2004.Includes bibliographical references and index.xiv, 481 pages.
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