319 research outputs found
sj-docx-1-cat-10.1177_10760296231221986 - Supplemental material for Cardiac Arrest-Associated Coagulopathy Could Predict 30-day Mortality: A Retrospective Study from Medical Information Mart for Intensive Care IV Database
No full textSupplemental material, sj-docx-1-cat-10.1177_10760296231221986 for Cardiac Arrest-Associated Coagulopathy Could Predict 30-day Mortality: A Retrospective Study from Medical Information Mart for Intensive Care IV Database by Jingwei Duan, Hongxia Ge, Wenyang Fan, Lanfang Du, Hua Zhang, Ayijiang Jiamaliding, Baomin Duan and Qingbian Ma in Clinical and Applied Thrombosis/Hemostasis</p
The effects of visual imagery on face identification: an ERP study
No full textThe present study tested the hypothesis that the effects of mental imagery on subsequent perception occur at a later matching stage in perceptual identification, but not in the early perceptual stage as in perceptual detection. The behavioral results suggested that the effect of visual imagery on visual identification is content-specific, i.e., imagining a congruent face facilitates face identification, whereas a mismatch between imagery and perception leads to an interference effect. More importantly, the ERP results revealed that a more negative N2 response to the subsequent visual face stimuli was elicited over fronto-central sites in the mismatch and no-imagery conditions as compared to that in the match condition, with the early P1 and N170 components independent of manipulations. The latency and distribution of the neural effects demonstrate that the matching step, but not the earlier perceptual process, is affected by the preceding visual imagery in the context of face identification. We discuss these results in a broader context that the imagery-perception interaction may depend on task demand
Digital and Field Techniques
No full textThe purpose of this module is to demonstrate the instruments and field techniques used to collect data on the physical parameters of lakes and oceans. Characteristics that were measured included turbidity, conductivity, dissolved oxygen, temperature, current speed and direction, wind speed and direction, pH, and bottom sediment characteristics. Lab exercise ideas are provided, but actual lab activities will depend on the frequency, time period, and quality of data collection. A lab exercise is provided to show how the collected field data were imported into Excel spreadsheet format and mapped. Techniques for using the collected field data to prepare spatial maps of water characteristics are also provided. Educational levels: High school, Undergraduate lower division, Undergraduate upper division
How fast can a shoreline change?
No full textShoreline residents have identified shoreline and bluff erosion as a critical problem along some parts of the Great Lakes. The rate of shore erosion is affected by the kind of land and rock materials, shoreline shape, current patterns, storm directions, and the use of shore protection structures. In this study, ArcView is used to compare the shoreline shape in five aerial photographs of Painesville (Ohio) Township Park from 1954-1999. The objectives are to 1. Recognize shoreline features on aerial photographs, 2. Visualize changes in a shoreline over time, and 3. Observe the effects of shoreline devices on rates of erosion. Educational levels: High school, Undergraduate lower division, Undergraduate upper division
Enhanced visible-light-driven photocatalytic activities of LiInO2 by Mo6+ -doping strategy
No full textA novel visible-light-driven photocatalyst of Mo-doped LiInO<sub>2</sub> nanocomposite was successfully synthesized through a sol-gel method. The effect of Mo-doping concentrations on the microstructures and properties of LiInO<sub>2</sub> was characterized by X-ray diffraction, scanning electron microscope, X-ray photoelectron spectroscopy, photoluminescence, and ultraviolet-visible absorption spectra. The photocatalytic properties of the as-prepared samples were evaluated by the photocatalytic degradation of methylene blue (MB) dye under visible-light irradiation. The results demonstrated that the photocatalytic activity of 6% Mo-LiInO<sub>2</sub> reached to 98.6%, which was much higher than that of the undoped photocatalyst LiInO<sub>2</sub> (only 46.8%). The enhanced photocatalytic activity is ascribed to Mo-doping strategy. The holes play an important role in the process of the photodegradation of MB. The superior photocatalytic activity of the as-prepared Mo-LiInO<sub>2</sub> nanocomposites suggests a potential application for organic dye degradation of wastewater remediation. This work provides a further understanding on tailoring the band structure of semiconductor photocatalyst for enhancing visible-light absorption and promoting electron-hole separation by Mo-doping strategy
Increased anticipatory contingent negative variation in posttraumatic stress disorder
No full textContains fulltext :
167881.pdf (Publisher’s version ) (Open Access)Altered anticipation processes are implicated across various clinical samples, but few studies focused on the posttraumatic stress disorder (PTSD). We measured contingent negative variation (CNV) in a choice reaction paradigm among 58 survivors of the Wenchuan earthquake, including 28 individuals who were diagnosed with PTSD and 30 without PTSD. Compared to the non-PTSD group, the PTSD group had significantly larger CNV amplitude. On the behavioral level, although the reaction times were comparable between groups, the PTSD group committed more errors than the non-PTSD group. Furthermore, the total PTSD symptom severity score as well as the re-experiencing symptom score were positively related to CNV amplitude. These results suggested that individuals with PTSD might be more alerted to and anticipate more to upcoming events in their environment, yet still have degraded performance in response to the stimulus
The public perspective of carbon capture and storage for CO2 emission reductions in China
No full textTo explore public awareness of carbon capture and storage (CCS), attitudes towards the use of CCS and the determinants of CCS acceptance in China, a study was conducted in July 2009 based on face-to-face interviews with participants across the country. The result showed that the awareness of CCS was low among the surveyed public in China, compared to other clean energy technologies. Respondents indicated a slightly supportive attitude towards the use of CCS as an alternative technology to CO2 emission reductions. The regression model revealed that in addition to CCS knowledge, respondents' understanding of the characteristics of CCS, such as the maturity of the technology, risks, capability of CO2 emission reductions, and CCS policy were all significant factors in predicting the acceptance of CCS. The findings suggest that integrating public education and communication into CCS development policy would be an effective strategy to overcome the barrier of low public acceptance.CCS CO2 emission reductions Low carbon energy technologies
Insulin-Like Growth Factor Signaling during Myogenesis.
No full textMyogenesis is the process of muscle development and growth. It involves a series of highly ordered cellular events – myoblast proliferation, cell cycle withdrawal, terminal differentiation, and cell fusion. Myogenesis requires the coordinated actions of various transcription factors and growth factors. Insulin-like growth factors (IGFs) stimulate both myoblast proliferation and differentiation. It remains elusive how these two mutually exclusive cellular responses can be elicited by the same growth factor. In order to address this question, I investigated the regulation of IGF signaling actions by both local IGF binding proteins (IGFBPs) and the cellular microenvironment.
First, I examined how IGF actions are regulated by the local IGFBPs during myogenesis. IGF-II stimulates myoblast differentiation and its own gene expression by a positive feedback mechanism via the PI3K-Akt pathway. IGFBP-5 is the major IGFBP expressed during myogenesis. Its expression is rapidly elevated and precedes the appreciable increase of IGF-II transcription. IGFBP-5 knockdown impairs myogenesis and suppresses IGF-II gene expression. Adding exogenous IGF or constitutively active Akt rescues the defects caused by IGFBP-5 knockdown. Furthermore, IGFBP-5 regulates IGF-II actions by binding to IGF. Together, these data suggest that under physiological conditions, IGFBP-5 promotes myoblast differentiation and potentiates IGF-II actions by binding to and switching on the IGF-II auto-regulation loop.
Second, I addressed how cellular microenvironment specifies IGF signaling outcomes. While IGF promotes myoblast differentiation under normoxia, it stimulates proliferation under hypoxia. IGF downstream signaling pathways – Akt-mTOR, p38, and Erk MAPK, are differentially regulated under hypoxia. Hypoxia inhibits the myogenic Akt-mTOR and p38 pathways by suppressing Akt signaling and inducing negative regulators. In contrast, Erk activity is enhanced under hypoxia leading to increased proliferation and decreased differentiation. p38 inhibition directly contributes to IGF-stimulated proliferation. Moreover, the altered IGF signaling outcomes are linked to the profoundly altered cellular metabolism in hypoxia. IGF increases cell proliferation under hypoxia by further enhancing HIF-1-mediated glycolysis.
In conclusion, IGF signaling during myogenesis is intricately regulated by both local IGFBPs and cellular microenvironment. These mechanisms determine whether cells respond to IGF signaling by proliferating or differentiating.PhDMolecular, Cellular, and Developmental BiologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/62414/1/renh_1.pd
Adaptability to elevated temperature and nitrogen addition is greater in a high-elevation population than in a low-elevation population of Hippophae rhamnoides
No full textHippophae rhamnoides L. is a broadleaf deciduous woody shrub occurring in southwest China, where it has been widely used in ecological restoration. In this study we investigated growth and physiological responses of 2-year-old healthy seedlings to elevated temperature, nitrogen (N) addition and their combination in two contrasting populations from high and low elevations. In closed-top chamber experiments, two populations were subjected to two temperature conditions (ambient temperature and temperature elevated by 2.2 +/- 0.2 degrees C) and two N levels (0 and 25 g N m(-2) a(-1)). Compared with the control, increases in total leaf area (TLA), total chlorophyll content (TC), light-saturated photosynthetic rate (P-max), guaiacol peroxidase activity (POD), catalase activity (CAT) and carbon isotope composition (delta C-13) were greater in the high-elevation population than in the low-elevation population under elevated temperature. On the other hand, decreases in root and shoot biomass ratio (RS), TC, P-max, light saturation point (L-SP), light compensation point (L-CP), superoxide dismutase (SOD), POD, CAT and delta C-13 were lower in the high-elevation population than in the low-elevation population under N addition. Moreover, the combination of elevated temperature and N addition decreased RS, P-max, apparent quantum efficiency (Phi), SOD, POD and delta C-13 significantly more in the low-elevation population than in the high-elevation population. These results demonstrated that there are different adaptive strategies among H. rhamnoides populations, the high-elevation population exhibiting higher adaptability to elevated temperature and N addition than the low-elevation population
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