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Prevalence of Bovine Congenital Pseudomyotonia carrier status in selected populations of the Chianina breed
No full textRenal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations
No full textRENAL DYSPLASIA (RD) is a developmental disorder of the renal parenchyma characterized by anomalous differentiation of the nephrons and collecting ducts. In veterinary medicine, it has been described in several species, including cattle. In particular, in Japanese Black cattle, RD shows autosomal recessive inheritance, caused by CLDN16 mutations. This short communication deals with a case of RD in twin Grey Alpine heifers which is not related to mutations of the CLDN16 gene.
RD should be considered when young animals show the following clinical findings: dullness, growth retardation, overgrowth of hooves and severe renal failure. Ultrasound can be strongly suggestive of RD, but only postmortem investigation can definitively confirm the disease. RD should be considered etiologically heterogeneous, as it is in human medicine.
Eight-month-old twin Grey Alpine heifers were referred due to severe depression, poor appetite, growth retardation and overgrowth of hooves. Clinical biochemistry indicated the presence of renal failure. Ultrasonographic examination showed a severe disorganization of the renal parenchyma. Major finding was an increased echogenicity of both the renal cortex and the renal medulla. On gross postmortem examination the kidneys were hypotrophic, firm and pale, and had a roughened and granular surface. At the cut surface, dense cortical and medullar fibrosis, and fibrous wedges extending from the pelvis to the cortex were evident. At histopathology the kidneys showed diffuse and massive infiltration of immature mesenchymal tissue forming a net with evident parallel ridges, connected with transversal bridges, which gave a pseudo-lobular appearance to the renal tissue. The cortex was thin and presented primitive tubules lined by cuboidal epithelium on a thickened basal membrane, and immature glomeruli at different developmental stages. The medulla showed persistent mesenchyme and many primitive tubules lined by pseudostratified, columnar, epithelial cells.
DNA of the affected animals, their dam as well as from a single unrelated animal, was screened for two different mutations of the CLDN16 gene responsible for inherited renal tubular dysplasia (RTD) in Japanese Black (Wagyu) cattle. The presence of a genomic deletion, such as that in Wagyu cattle, was excluded. Moreover, the re-sequencing of the PCR products revealed no polymorphisms affecting the coding sequence or consensus splice sites of CLDN16.
This study showed a nephrologic syndrome phenotypically overlapping RD in Japanese Black cattle but which is not associated with mutations affecting the CLDN16 gene.
Hopefully, this paper will alert bovine practitioners and breeders to the importance of reporting animals with the above-mentioned clinical findings to research or diagnostic centers for thorough evaluation
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Choroby dziedziczne bydla (Inherited diseases of cattle)
No full textThis review focus on the most important inherited disorders of cattle and the genomic basis is presented when known. In addition it deals with aspects that should be considered when dealing with this type of diseases and finally, a survey of different alterations in the bovine genome is presented
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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